Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Moderate to Severe Dry Eye Syndrome”

88 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 88 results

Testing effectiveness (Phase 2)Study completedNCT00349466
What this trial is testing

Safety and Efficacy Study of CF101 to Treat Keratoconjunctivitis Sicca

Who this might be right for
Keratoconjunctivitis Sicca
Can-Fite BioPharma 80
Not applicableEnded earlyNCT03803722
What this trial is testing

To Demonstrate the Non-inferiority of Eyestil Protection® Compared to Vismed® in Terms of Clinical Performance

Who this might be right for
Dry Eye Syndrome
SIFI SpA 21
Not applicableStudy completedNCT01562795
What this trial is testing

Efficacy of Nonsteroidal Anti-inflammatory Drugs in Treatment of Moderate and Severe Dry Eye Disease

Who this might be right for
Moderate to Severe Dry Eye Syndrome
Wenzhou Medical University 48
Post-approval studies (Phase 4)Study completedNCT01311609
What this trial is testing

A Multi-Site Post Marketing Surveillance Study for Systane in Indian Patients

Who this might be right for
Moderate to Severe Dry Eye
Alcon Research 300
Not applicableStudy completedNCT06375499
What this trial is testing

Performance and Safety of T2769 Versus Hylo-Forte® in the Treatment of Moderate to Severe Dry Eye Syndrome.

Who this might be right for
Dry Eye Syndrome
Laboratoires Thea 74
Testing effectiveness (Phase 2)Study completedNCT00679718
What this trial is testing

INS365 Ophthalmic Solution in Patients With Moderate to Severe Dry Eye Disease

Who this might be right for
Dry Eye Disease
Merck Sharp & Dohme LLC 150
Testing effectiveness (Phase 2)Study completedNCT04084483
What this trial is testing

A Study Assessing the Safety, Efficacy, and Optimum Dosage of K-161 in Subjects With Moderate to Severe Dry Eye Disease

Who this might be right for
Dry Eye Disease
Kowa Research Institute, Inc. 238
Testing effectiveness (Phase 2)Ended earlyNCT04035668
What this trial is testing

Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sjögren's Syndrome

Who this might be right for
Sjögren Syndrome
Novartis Pharmaceuticals 73
Not applicableLooking for participantsNCT07412860
What this trial is testing

Clinical Investigation Between the Topical Administration of a Tear Substitute With Ancillary Medicinal Substance and Hyaluronic Acid 0.3% (FBV_01) vs Hyaluronic Acid 0.3% in Subjects in the Treatment From Moderate to Severe DED

Who this might be right for
Dry Eye SyndromesDry Eye Disease (DED)
FB Vision S.p.A 74
Large-scale testing (Phase 3)Study completedNCT04541888
What this trial is testing

Assess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Moderate to Severe Dry Eye Disease

Who this might be right for
Dry Eye
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. 644
Testing effectiveness (Phase 2)UnknownNCT04217785
What this trial is testing

Umbilical Cord Serum Versus Conventional Eyedrops

Who this might be right for
Dry Eye Syndromes
National University of Malaysia 102
Post-approval studies (Phase 4)Study completedNCT02986750
What this trial is testing

Influence of Three Different Formulations of Lachrymal Substitutes on Tear Film Thickness and Other Signs and Symptoms in Patients With Moderate to Severe Dry Eye Syndrome

Who this might be right for
Dry Eye Syndromes
Medical University of Vienna 120
Not applicableActive Not RecruitingNCT04685109
What this trial is testing

3 Month Study of Alocross Versus Vismed in Adults With Dry Eye Disease Related to Keratitis or Keratoconjunctivitis

Who this might be right for
Dry Eye Syndromes
Santen SAS 80
Not applicableLooking for participantsNCT07593885
What this trial is testing

Evaluate the Performance and Safety of Artelac® Complete MDO® Versus VISMED® MULTI Eye Drops in the Management of Moderate to Severe Dry Eye Disease

Who this might be right for
Dry Eye
Dr. Gerhard Mann chem.-pharm. Fabrik GmbH 160
Post-approval studies (Phase 4)WithdrawnNCT07529899
What this trial is testing

Evaluate the Efficacy and Safety of Amnion Membrane Disc Allograft vs Standard of Care in Participants With Dry Eye Disease

Who this might be right for
Dry Eye Disease (DED)
Cellution Biologics
Large-scale testing (Phase 3)UnknownNCT05245604
What this trial is testing

Evaluating the Efficacy and Safety of TJO-087 in Moderate to Severe Dry Eye Disease Patients

Who this might be right for
Dry Eye Syndrome
Taejoon Pharmaceutical Co., Ltd. 182
Large-scale testing (Phase 3)UnknownNCT06291194
What this trial is testing

Efficacy and Safety of AJU-S56 5% in Dry Eye Syndrome Patients

Who this might be right for
Dry Eye Syndromes
AJU Pharm Co., Ltd. 396
Large-scale testing (Phase 3)Study completedNCT01235234
What this trial is testing

Trial of CF101 to Treat Patients With Dry Eye Disease

Who this might be right for
Keratoconjunctivitis Sicca
Can-Fite BioPharma 236
Large-scale testing (Phase 3)Active Not RecruitingNCT06245408
What this trial is testing

A Safety and Efficacy Study of Dazodalibep in Participants With Sjögren's Syndrome (SS) With Moderate-to-Severe Symptom State

Who this might be right for
Sjögren's Syndrome (SS)
Amgen 434
Post-approval studies (Phase 4)UnknownNCT00704275
What this trial is testing

Comparison of Efficacy, Safety and Anti-Inflammatory Effect Between Topical 0.05%Cyclosporine A Emulsion and REFRESH® in Patients With Moderate to Severe Dry Eyes

Who this might be right for
Dry Eye
Chulalongkorn University 60
Next Page