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Results for “Moderate to Severe Functional Impairments”

Showing 20 of 0 results

Early research (Phase 1)Study completedNCT05935033
What this trial is testing

Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Emraclidine

Who this might be right for
Hepatic Impairment
AbbVie 38
Early research (Phase 1)Study completedNCT05224609
What this trial is testing

Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction

Who this might be right for
Moderate Hepatic ImpairmentSevere Hepatic ImpairmentHealthy Volunteers
Pfizer 21
Early research (Phase 1)Study completedNCT05940402
What this trial is testing

Evaluate Pharmacokinetic and Safety Trial of Emraclidine in Participants With Renal Impairment Compared With Participants With Normal Renal Function

Who this might be right for
Renal Impairment
AbbVie 58
Early research (Phase 1)Study completedNCT01443429
What this trial is testing

A Pharmacokinetic Study of TRK-100STP in Japanese Patients With Renal Impairment

Who this might be right for
Renal Impairment
Toray Industries, Inc 24
Early research (Phase 1)Study completedNCT00768404
What this trial is testing

Evaluate the Pharmacokinetics of VI-0521 Subjects With Renal Impairment

Who this might be right for
Renal Impairment
VIVUS LLC 32
Early research (Phase 1)Looking for participantsNCT07401862
What this trial is testing

Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.

Who this might be right for
Hepatic Insufficiency
Eli Lilly and Company 36
Early research (Phase 1)Looking for participantsNCT07231991
What this trial is testing

Learn How the Body Processes the Study Medicine Called Vepdegestrant in People With Loss of Liver Function

Who this might be right for
Healthy Participants
Pfizer 24
Early research (Phase 1)Study completedNCT03192111
What this trial is testing

Evaluate the Pharmacokinetics of Entinostat in Adult Subjects With Normal and Impaired Renal Function

Who this might be right for
Renal ImpairmentHealthy Volunteer
Syndax Pharmaceuticals 40
Early research (Phase 1)Active Not RecruitingNCT07168356
What this trial is testing

Evaluate Blood Levels of Bepirovirsen in Adult Participants With Severe or Moderate Kidney Disease

Who this might be right for
Hepatitis B
GlaxoSmithKline 32
Early research (Phase 1)Study completedNCT01817985
What this trial is testing

Evaluate the Pharmacokinetics of GS-5816 in Subjects With Normal Hepatic Function and Moderate or Severe Hepatic Impairment

Who this might be right for
Chronic Hepatitis C
Gilead Sciences 33
Early research (Phase 1)Study completedNCT04656795
What this trial is testing

PK Study in Subjects With Renal Impairment (Severe and if Required Mild & Moderate) Compared to Subjects With Normal Renal Function

Who this might be right for
Renal ImpairmentNormal Renal Function
Tanabe Pharma America, Inc. 32
Early research (Phase 1)Ended earlyNCT04241835
What this trial is testing

Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function

Who this might be right for
Hepatic ImpairmentAdvanced Malignant Solid Tumor
Epizyme, Inc. 18
Early research (Phase 1)Study completedNCT05117294
What this trial is testing

ASP0367 in People With Kidneys That do Not Work Well and in Healthy People

Who this might be right for
Renal ImpairmentHealthy Volunteers
Astellas Pharma Global Development, Inc. 13
Early research (Phase 1)Looking for participantsNCT07165002
What this trial is testing

The Pharmacokinetics and Safety of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment

Who this might be right for
HealthyHepatic Insufficiency
Eli Lilly and Company 32
Early research (Phase 1)Study completedNCT03913000
What this trial is testing

Evaluate ID-085 in People With Mild, Moderate, and Severe Kidney Disease

Who this might be right for
Renal Impairment
Idorsia Pharmaceuticals Ltd. 32
Early research (Phase 1)Study completedNCT01046058
What this trial is testing

TMC435-TiDP16-C113: A Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics of TMC435

Who this might be right for
Hepatitis C Virus
Tibotec Pharmaceuticals, Ireland 23
Early research (Phase 1)Study completedNCT05718648
What this trial is testing

Test How BI 1015550 is Taken up in the Blood of People With and Without Kidney Problems

Who this might be right for
Renal InsufficiencyHealthy
Boehringer Ingelheim 26
Early research (Phase 1)Study completedNCT04056468
What this trial is testing

Evaluate Pharmacokinetics (PK) and Safety of Oral Mobocertinib in Participants With Moderate or Severe Hepatic Impairment (HI) and Normal Hepatic Function

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Millennium Pharmaceuticals, Inc. 24
Early research (Phase 1)Study completedNCT06952634
What this trial is testing

An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage

Who this might be right for
Hepatic Impairment
Alumis Inc 32
Early research (Phase 1)Study completedNCT01504165
What this trial is testing

Pharmacokinetics in Subjects With Renal Impairment

Who this might be right for
Renal Impairment
Merck KGaA, Darmstadt, Germany 32
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