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Results for “Moderate to Severe Rheumatoid Arthritis”

261 trials

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Showing 20 of 261 results

Large-scale testing (Phase 3)Ended earlyNCT03970837
What this trial is testing

Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Conventional Synthetic (cs)/Biologic (b) Disease Modifying Anti-rheumatic Drugs (DMARDs)

Who this might be right for
Arthritis, Rheumatoid
GlaxoSmithKline 1,764
Testing effectiveness (Phase 2)Active Not RecruitingNCT06859294
What this trial is testing

LY3541860 in Adult Participants With Moderately to Severely Active Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Eli Lilly and Company 35
Not applicableStudy completedNCT02608112
What this trial is testing

Study to Describe Real World Drug Retention Rate of the Tocilizumab at One Year

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 291
Large-scale testing (Phase 3)Study completedNCT00531817
What this trial is testing

Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 619
Early research (Phase 1)Looking for participantsNCT07041099
What this trial is testing

CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease

Who this might be right for
SjögrenSjogren DiseaseSjogren's Syndrome
Cullinan Therapeutics Inc. 36
Testing effectiveness (Phase 2)Study completedNCT02504671
What this trial is testing

Study to Evaluate the Efficacy and Safety of GSK3196165 Plus Methotrexate in Subjects With Active Moderate-Severe Rheumatoid Arthritis

Who this might be right for
Arthritis, Rheumatoid
GlaxoSmithKline 222
Testing effectiveness (Phase 2)Ended earlyNCT02843659
What this trial is testing

Proof of Concept Study to Evaluate the Efficacy and Safety of BMS-931699 (Lulizumab) or BMS-986142 in Primary Sjögren's Syndrome

Who this might be right for
Sjögren's Syndrome
Bristol-Myers Squibb 45
Large-scale testing (Phase 3)Study completedNCT02222493
What this trial is testing

PF-06438179 (Infliximab-Pfizer) and Infliximab in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis (REFLECTIONS B537-02).

Who this might be right for
Rheumatoid Arthritis
Pfizer 650
Large-scale testing (Phase 3)Active Not RecruitingNCT06741969
What this trial is testing

Nipocalimab in Moderate to Severe Sjogren's Disease

Who this might be right for
Sjogrens Syndrome
Janssen Research & Development, LLC 655
Testing effectiveness (Phase 2)Ended earlyNCT01612377
What this trial is testing

Long Term Safety Trial of z102 and Prednisone in Patients With Moderate to Severe Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Zalicus 18
Large-scale testing (Phase 3)Study completedNCT02265705
What this trial is testing

Baricitinib (LY3009104) in Participants With Rheumatoid Arthritis (RA)

Who this might be right for
Rheumatoid Arthritis
Eli Lilly and Company 290
Very early researchLooking for participantsNCT07526350
What this trial is testing

MTS109 in Patients With Refractory Autoimmune Diseases

Who this might be right for
Systemic Lupus ErythematosusIdiopathic Inflammatory MyopathiesSystemic Sclerosis (SSc)+2 more
Shanghai Changzheng Hospital 15
Testing effectiveness (Phase 2)Study completedNCT02638948
What this trial is testing

Efficacy and Safety Study of BMS-986142 in Patients With Moderate to Severe Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Bristol-Myers Squibb 508
Testing effectiveness (Phase 2)UnknownNCT06306339
What this trial is testing

Assess the Efficacy and Safety of Burfiralimab (hzVSF-v13) and DMRD (Disease-modifying Antirheumatic Drug)

Who this might be right for
Moderate to Severe Rheumatoid Arthritis
ImmuneMed, Inc. 60
Large-scale testing (Phase 3)Study completedNCT01655381
What this trial is testing

A Long-Term Extension Study of WA19926 on the Safety of Tocilizumab (RoActemra/Actemra) in Participants With Early Moderate to Severe Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 15
Large-scale testing (Phase 3)Study completedNCT01668966
What this trial is testing

A Long Term Extension Study of WA19926 (NCT01007435) of Tocilizumab (RoActemra/Actemra) in Participants With Early, Moderate to Severe Rheumatoid Arthritis (RA)

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 23
Large-scale testing (Phase 3)Study completedNCT01970475
What this trial is testing

Efficacy and Safety Study of ABP 501 Compared to Adalimumab in Subjects With Moderate to Severe Rheumatoid Arthritis

Who this might be right for
Arthritis, Rheumatoid
Amgen 526
Post-approval studies (Phase 4)Ended earlyNCT01927757
What this trial is testing

Evaluating Etanercept Use in Patients With Moderate to Severe Rheumatoid Arthritis Who Have Lost Response to Adalimumab

Who this might be right for
Moderate to Severe Rheumatoid Arthritis
Amgen 90
Testing effectiveness (Phase 2)Study completedNCT05460832
What this trial is testing

Phase 2b Study of MBS2320 in Participants With Methotrexate-Refractory RA

Who this might be right for
Rheumatoid Arthritis
Modern Biosciences Ltd 248
Large-scale testing (Phase 3)Study completedNCT02744755
What this trial is testing

Clinical Trial to Compare Treatment With GP2017 and Humira® in Patients With Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Sandoz 353
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