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Results for “Molecular Mechanisms of Pharmacological Action”

141 trials

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Showing 20 of 141 results

Testing effectiveness (Phase 2)Looking for participantsNCT06463665
What this trial is testing

Efficacy & Safety of Olvimulogene Nanivacirepvec & Platinum-doublet + Physician's Choice of Immune Checkpoint Inhibitor Compared to Docetaxel in NSCL Cancer

Who this might be right for
Advanced Non-squamous Non-small-cell Lung CancerAdvanced Squamous Non-Small Cell Lung CarcinomaMetastatic Non-squamous Non Small Cell Lung Cancer+5 more
Genelux Corporation 142
Testing effectiveness (Phase 2)Looking for participantsNCT06511908
What this trial is testing

Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression

Who this might be right for
SuicideDepressive Disorder, Treatment-ResistantKetamine+10 more
National Institute of Mental Health (NIMH) 50
Early research (Phase 1)Looking for participantsNCT06796361
What this trial is testing

Role of the Serotonin 2A Receptor in Psilocybin-induced Altered States of Consciousness

Who this might be right for
Healthy
University Hospital, Basel, Switzerland 16
Early research (Phase 1)UnknownNCT05143424
What this trial is testing

Evaluation of the Interactions of Cannabidiol (CBD) With Morphine

Who this might be right for
Opioid Use Disorder
National Institute on Drug Abuse (NIDA) 60
Early research (Phase 1)Study completedNCT03733574
What this trial is testing

LY03005 vs Pristiq

Who this might be right for
Major Depressive Disorder
Luye Pharma Group Ltd. 56
Not applicableStudy completedNCT04736472
What this trial is testing

Implementing Pharmacogenetic Testing in Gastrointestinal Cancers

Who this might be right for
Gastrointestinal Cancer
Abramson Cancer Center at Penn Medicine 552
Large-scale testing (Phase 3)Study completedNCT01701401
What this trial is testing

Safety and Efficacy of Ledipasvir/Sofosbuvir Fixed-Dose Combination (FDC) With and Without Ribavirin for the Treatment of HCV

Who this might be right for
Chronic Hepatitis C Virus
Gilead Sciences 870
Early research (Phase 1)Study completedNCT02577250
What this trial is testing

Ketamine Infusions for PTSD and Treatment-Resistant Depression

Who this might be right for
Depressive Disorder, Treatment-ResistantStress Disorders, Post-Traumatic
Minneapolis Veterans Affairs Medical Center 20
Early research (Phase 1)Study completedNCT04080297
What this trial is testing

Dose Escalation Study in Female Subjects With Breast Cancer Receiving Aromatase Inhibitor or Tamoxifen

Who this might be right for
Vasomotor Symptoms (VMS)
Que Oncology 21
Post-approval studies (Phase 4)Looking for participantsNCT05585125
What this trial is testing

A Preliminary Study for INFORMED

Who this might be right for
Heart FailureHeart Failure, DiastolicHeart Failure With Preserved Ejection Fraction+2 more
Weill Medical College of Cornell University 18
Large-scale testing (Phase 3)Looking for participantsNCT06679140
What this trial is testing

Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

Who this might be right for
COVID-19 SARS-CoV-2 Infection
Pfizer 2,330
Testing effectiveness (Phase 2)WithdrawnNCT00869869
What this trial is testing

Melatonin Supplementation to Improve Sleep in Patients With Heart Failure

Who this might be right for
Heart FailureSleep Disorders
Brigham and Women's Hospital
Large-scale testing (Phase 3)Study completedNCT04368559
What this trial is testing

Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation

Who this might be right for
CandidemiaMycosesFungal Infection+7 more
Mundipharma Research Limited 602
Large-scale testing (Phase 3)Ended earlyNCT01009593
What this trial is testing

Efficacy and Tolerability of ABT-869 Versus Sorafenib in Advanced Hepatocellular Carcinoma (HCC)

Who this might be right for
Hepatocellular Carcinoma Non-resectableHepatocellular Carcinoma RecurrentCarcinoma, Hepatocellular+10 more
Abbott 1,035
Early research (Phase 1)Study completedNCT04922593
What this trial is testing

Relative Bioavailability of LY03010 Compared to Listed Drug

Who this might be right for
SchizophreniaPsychotic DisordersMood Disorders+9 more
Luye Pharma Group Ltd. 281
Testing effectiveness (Phase 2)WithdrawnNCT03610282
What this trial is testing

EEG Study of IV Methylphenidate-Induced Emergence From Propofol Sedation

Who this might be right for
Anesthesia
Massachusetts General Hospital
Large-scale testing (Phase 3)Study completedNCT03494920
What this trial is testing

DIRECT-SAFE: A Randomized Controlled Trial of DIRECT Endovascular Clot Retrieval Versus Standard Bridging Thrombolysis With Endovascular Clot Retrieval

Who this might be right for
Ischemic Stroke
Neuroscience Trials Australia 295
Testing effectiveness (Phase 2)Study completedNCT03340493
What this trial is testing

Determining the Optimal Dose of Tenecteplase Before Endovascular Therapy for Ischaemic Stroke (EXTEND-IA TNK Part 2)

Who this might be right for
Ischemic Stroke
Neuroscience Trials Australia 300
Testing effectiveness (Phase 2)Looking for participantsNCT04198766
What this trial is testing

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

Who this might be right for
Solid TumorNon-Small Cell Lung CancerHead and Neck Cancer+5 more
Inhibrx Biosciences, Inc 340
Not applicableWithdrawnNCT01799499
What this trial is testing

A Prospective Open Label Comparative Dose Ranging Study Evaluating the Effect of Pre-TURBT Intravesical Instillation of Mitomycin C (MMC) Mixed With TC-3 Gel in Patients With Non Muscle Invasive Bladder Cancer (NMIBC)

Who this might be right for
Non Muscle Invasive Bladder Cancer
UroGen Pharma Ltd.
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