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Results for “Molecular Targeted Therapy”

152 trials

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Showing 20 of 152 results

Not applicableLooking for participantsNCT06481228
What this trial is testing

Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL

Who this might be right for
Philadelphia Positive Acute Lymphoblastic LeukemiaAcute Lymphoblastic Leukemia, Adult
Institute of Hematology & Blood Diseases Hospital, China 82
Early research (Phase 1)Study completedNCT04023669
What this trial is testing

Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors

Who this might be right for
Brain TumorBrain Tumor, RecurrentBrain Tumor, Refractory+10 more
St. Jude Children's Research Hospital 21
Not applicableLooking for participantsNCT06669377
What this trial is testing

TACE Combined With ICIs Plus MTT After 125I Irradiation Stent Placement in HCC With Main PVTT.

Who this might be right for
Hepatocellular Carcinoma
Zhongda Hospital 444
Large-scale testing (Phase 3)Looking for participantsNCT06988475
What this trial is testing

DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations

Who this might be right for
Solid TumourHaematological MalignancyMalignant Neoplasm+8 more
Cancer Research UK 30
Testing effectiveness (Phase 2)Study completedNCT04720131
What this trial is testing

Camrelizumab Combined With Apatinib and Capecitabine in Patients With Advanced Biliary Tract Cancer.

Who this might be right for
Biliary Tract CancerAnti-PD-1 TherapyTargeted Molecular Therapy+1 more
Beijing Friendship Hospital 28
Very early researchNot Yet RecruitingNCT07280793
What this trial is testing

CAR-T Cell Efficacy With Molecular Imaging in Multiple Myeloma

Who this might be right for
Non-invasive CAR-T Cell MonitoringBCMA-targeted PET ImagingCAR-T Cell Biodistribution and Persistence+1 more
Xuzhou Medical University 10
Not applicableStudy completedNCT05923268
What this trial is testing

Molecular Imaging of HER2 Expression in Breast Cancer Using [99mTc]Tc-G3-(G3S)3C Before Chemo/Targeted Therapy

Who this might be right for
Breast Cancer Female
Tomsk National Research Medical Center of the Russian Academy of Sciences 10
Large-scale testing (Phase 3)Looking for participantsNCT05770037
What this trial is testing

DETERMINE Trial Treatment Arm 01: Alectinib in Adult, Paediatric and Teenage/Young Adult Patients With ALK Positive Cancers

Who this might be right for
Haematological MalignancyMalignant NeoplasmLymphoproliferative Disorders+8 more
Cancer Research UK 30
Testing effectiveness (Phase 2)Looking for participantsNCT07049055
What this trial is testing

A Clinical Trial to Evaluate EDV Nanocell Therapy With Gemcitabine and Nab-paclitaxel in Pancreatic Cancer

Who this might be right for
Pancreatic Cancer, MetastaticPDAC - Pancreatic Ductal Adenocarcinoma
Engeneic Pty Limited 144
Not applicableLooking for participantsNCT02139020
What this trial is testing

Collection of Plasma Samples for Squamous Cell Carcinoma of the Head and Neck Patients

Who this might be right for
Squamous Cell Carcinoma of the Head and Neck
Cliniques universitaires Saint-Luc- Université Catholique de Louvain 400
Testing effectiveness (Phase 2)Ended earlyNCT00671645
What this trial is testing

Preoperative Combined RadioChemo-Molecular Target Therapy With Capecitabine, Bevacizumab, and Radiotherapy

Who this might be right for
Rectal Cancer
Austrian Breast & Colorectal Cancer Study Group 8
Not applicableUnknownNCT01566019
What this trial is testing

Molecular Screening for Cancer Treatment Optimization

Who this might be right for
Metastatic Solid Tumors (Any Localization)
Gustave Roussy, Cancer Campus, Grand Paris 2,150
Large-scale testing (Phase 3)Looking for participantsNCT05722886
What this trial is testing

DETERMINE (Determining Extended Therapeutic Indications for Existing Drugs in Rare Molecularly Defined Indications Using a National Evaluation Platform Trial) - Master Screening Protocol

Who this might be right for
Haematological MalignancySolid Tumour
Cancer Research UK 825
Testing effectiveness (Phase 2)UnknownNCT05981157
What this trial is testing

Anrotinib and Tirelizumab in First-line Treatment of RM-NPC

Who this might be right for
Nasopharyngeal Carcinoma
Zhongshan People's Hospital, Guangdong, China 27
Post-approval studies (Phase 4)UnknownNCT05187208
What this trial is testing

PARP Inhibitor Oral Maintenance in Low-Risk Ovarian Cancer

Who this might be right for
Epithelial Ovarian CancerOvarian CancerOvarian Cancer Stage III+1 more
Seoul National University Hospital 102
Not applicableStudy completedNCT01052532
What this trial is testing

Molecular Mechanisms of Mitral Regurgitation-Aim 2

Who this might be right for
Mitral Regurgitation
University of Alabama at Birmingham 65
Testing effectiveness (Phase 2)Looking for participantsNCT05845450
What this trial is testing

Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)

Who this might be right for
Colorectal CancerResectable Colorectal Carcinoma
Gruppo Oncologico del Nord-Ovest 140
Large-scale testing (Phase 3)Looking for participantsNCT05786716
What this trial is testing

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations

Who this might be right for
Haematological MalignancyColorectal NeoplasmsUrinary Bladder Neoplasm+8 more
Cancer Research UK 30
Not applicableUnknownNCT02597179
What this trial is testing

Genome Sequencing in Refractory Breast Cancer to Molecular Targeted Therapy and Young Breast Cancer

Who this might be right for
Breast Cancer
Samsung Medical Center 350
Testing effectiveness (Phase 2)WithdrawnNCT00343759
What this trial is testing

Presurgical Therapy With Lapatinib to Explore Molecular Determinants of Response to EGFR/erbB2 Targeted Therapy

Who this might be right for
Breast Cancer
University of Pennsylvania
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