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Results for “Monoclonal Antibody, Human”

513 trials

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Showing 20 of 513 results

Large-scale testing (Phase 3)Study completedNCT01302860
What this trial is testing

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Who this might be right for
Cryopyrin-associated Periodic SyndromesFamilial Cold Autoinflammatory SyndromeMuckle-Wells Syndrome+1 more
Novartis Pharmaceuticals 17
Early research (Phase 1)Study completedNCT02383212
What this trial is testing

Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies

Who this might be right for
Advanced CancerAdvanced Malignancies
Regeneron Pharmaceuticals 398
Early research (Phase 1)UnknownNCT00300807
What this trial is testing

Study of XTL6865 in Patients With Chronic Hepatitis C Virus Infection

Who this might be right for
Hepatitis C
XTL Biopharmaceuticals 36
Early research (Phase 1)Looking for participantsNCT07610772
What this trial is testing

Safety and Antiviral Activity of a Monoclonal Hepatitis B Antibody: a Phase 1b, Open-label Trial in Individuals With Chronic Hepatitis D Infection

Who this might be right for
Hepatitis D, ChronicHepatitis B Chronic Infection
Aarhus University Hospital 15
Not applicableLooking for participantsNCT06659029
What this trial is testing

Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users

Who this might be right for
Systemic Lupus Erythematosus
AstraZeneca 442
Testing effectiveness (Phase 2)Looking for participantsNCT06094881
What this trial is testing

A Prospective, One-arm and Open Clinical Study of Obinutuzumab in the Treatment of Pediatric Primary Immune Thrombocytopenia (ITP)

Who this might be right for
Immune ThrombocytopeniaTreatment
Institute of Hematology & Blood Diseases Hospital, China 60
Testing effectiveness (Phase 2)Study completedNCT01240720
What this trial is testing

A Dose Finding and Efficacy Study of the Tumour Targeting Human 131I-F16SIP Monoclonal Antibody in Patients With Cancer

Who this might be right for
Cancer
Philogen S.p.A. 65
Large-scale testing (Phase 3)Study completedNCT00465985
What this trial is testing

Efficacy, Safety, and Tolerability of ACZ885 in Patients With Muckle-Wells Syndrome

Who this might be right for
Muckle Wells Syndrome
Novartis 35
Early research (Phase 1)Study completedNCT01950325
What this trial is testing

VRC 601: A Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC HIVMAB060-00-AB (VRC01), With Broad HIV-1 Neutralizing Activity, Administered Intravenously or Subcutaneously to HIV-Infected...

Who this might be right for
HIV-1 InfectionNeutralizing AntibodyMonoclonal Antibody+2 more
National Institute of Allergy and Infectious Diseases (NIAID) 27
Early research (Phase 1)Study completedNCT00007163
What this trial is testing

Monoclonal Antibody Treatment of Crohn's Disease

Who this might be right for
Crohn's Disease
National Institute of Allergy and Infectious Diseases (NIAID) 40
Early research (Phase 1)Active Not RecruitingNCT07762001
What this trial is testing

Study to Evaluate the Safety and Tolerability of AD-NP1 in Healthy Human Adult Volunteers

Who this might be right for
Maximum Tolerated DoseDose Escalation
Arjun Deb, MD 36
Testing effectiveness (Phase 2)Study completedNCT01008982
What this trial is testing

Efficacy and Safety of Belimumab in Primary Sjögren's Syndrome

Who this might be right for
Sjögren's Syndrome
University of Udine 15
Testing effectiveness (Phase 2)WithdrawnNCT06245291
What this trial is testing

Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection

Who this might be right for
Hepatitis B, Chronic
Arbutus Biopharma Corporation
Early research (Phase 1)Study completedNCT01660360
What this trial is testing

Phase I Trial of Tanibirumab in Advanced or Metastatic Cancer

Who this might be right for
Advanced CancerMetastatic Cancer
PharmAbcine 26
Testing effectiveness (Phase 2)Study completedNCT00657189
What this trial is testing

Evaluate Safety and Tolerability of Subcutaneous Doses of MEDI-545 in Subjects With Lupus

Who this might be right for
Lupus Erythematosus, SystemicLupus
MedImmune LLC 87
Very early researchUnknownNCT06360250
What this trial is testing

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of the Fully Human Anti-tetanus Toxin Monoclonal Antibody A82 / B86 Injection Combination Formulation

Who this might be right for
Clostridium Tetanus
Changchun BCHT Biotechnology Co. 190
Testing effectiveness (Phase 2)Looking for participantsNCT06669247
What this trial is testing

Assess the Safety and Anti-Tumor Activity of REGN7945 in Combination With Linvoseltamab in Adult Participants With Relapsed/Refractory Multiple Myeloma

Who this might be right for
Relapsed/Refractory Multiple Myeloma
Regeneron Pharmaceuticals 186
Early research (Phase 1)Ended earlyNCT03843359
What this trial is testing

A First Time in Human (FTIH) Study of GSK3745417 Administered to Participants With Advanced Solid Tumors

Who this might be right for
Neoplasms
GlaxoSmithKline 97
Early research (Phase 1)Study completedNCT03463473
What this trial is testing

A Phase I Study of MSB2311 in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumors
Transcenta Therapeutics (Hangzhou) Co., Ltd. 42
Large-scale testing (Phase 3)Study completedNCT00409682
What this trial is testing

Efficacy and Safety of Adalimumab in Pediatric Subjects With Moderate to Severe Crohn's Disease

Who this might be right for
Crohn's Disease
Abbott 192
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