Not applicableLooking for participantsNCT07139899What this trial is testingDownstream Effects of Airway Mucus Plugs on 129Xenon MRI in Severe AsthmaWho this might be right forSevere Asthma Bastiaan Driehuys 5
Not applicableLooking for participantsNCT05757583What this trial is testingImpact of Metabolic Dysfunction and Mucus Plugging on Asthma PhysiologyWho this might be right forAsthma University of California, San Francisco 80
Not applicableLooking for participantsNCT06069817What this trial is testingImpact of High Flow Therapy on Complications Related to Airway StentingWho this might be right forAirway ObstructionRespiratory InfectionMucus; Plug Cardarelli Hospital 30
Post-approval studies (Phase 4)Looking for participantsNCT07053423What this trial is testingInvestigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.Who this might be right forChronic Obstructive Pulmonary Disease Sanofi 218
Early research (Phase 1)Study completedNCT05220605What this trial is testingNebulised BromAc in Healthy VolunteersWho this might be right forCOVID-19 PneumoniaBromelains Adverse ReactionAcetylcysteine Adverse Reaction+2 more Mucpharm Pty Ltd 12
Post-approval studies (Phase 4)Study completedNCT04400318What this trial is testingThe Effect of Dupilumab on Lung Inflammation and Related Changes in Airway Volumes Detectable by Functional Respiratory Imaging in Patients With Moderate-severe AsthmaWho this might be right forAsthma Sanofi 109
Not applicableLooking for participantsNCT06985225What this trial is testingEvaluation of Ventilation Defects Downstream of Mucus Plugs in Patients With Severe AsthmaWho this might be right forSevere Asthma University of Kansas Medical Center 5
Not applicableWithdrawnNCT04514913What this trial is testingStudy of Focal Airway Disease in Asthma Using Image Guided BronchoscopyWho this might be right forAsthmaMucus; Plug, Tracheobronchial University of California, San Francisco
Not applicableTemporarily pausedNCT04266873What this trial is testingFeasibility Study of the AffloVest in BronchiectasisWho this might be right forBronchiectasis Papworth Hospital NHS Foundation Trust 30
Not applicableLooking for participantsNCT07362667What this trial is testingThe Efficacy and Safety of Bronchoscopic Airway Clearance and Amphotericin B Spraying in Patients With ABPAWho this might be right forABPAAllergic Bronchopulmonary AspergillosisAllergic Bronchopulmonary Aspergillosis (ABPA)+4 more Qianfoshan Hospital 44
Not applicableWithdrawnNCT05748912What this trial is testingLung Function Outcomes Following Removal of Airway Mucus Plugs in Patients With Asthma (FOCUS)Who this might be right forAsthma University of California, San Francisco
Not applicableLooking for participantsNCT07025200What this trial is testingDETACT sEvere asThmAtiC paTients - a Pilot StudyWho this might be right forAsthma Medical University of Vienna 10
Not applicableUnknownNCT05800379What this trial is testingStudy on Hospitalization of Children With Bronchial AsthmaWho this might be right forAsthma in Children Beijing Children's Hospital 470
Post-approval studies (Phase 4)Looking for participantsNCT06152653What this trial is testingThe Effects of Positive Airway Pressure on the Mucolytic Effects of NAC (TEAM)Who this might be right forAsthmaCOPD University of California, San Francisco 40
Not applicableLooking for participantsNCT06201494What this trial is testingProspective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and AdolescentsWho this might be right forAsthmaAsthma in ChildrenDyspnea+8 more Charles University, Czech Republic 80
Not applicableUnknownNCT03316079What this trial is testingEfficacity and Safety of Mechanical Insufflation-exsufflation on ICUWho this might be right forMucus RetentionMechanical Ventilation ComplicationMucus; Plug, Tracheobronchial University Hospital, Bordeaux 26
Large-scale testing (Phase 3)UnknownNCT03870646What this trial is testingNebulized hypErtonic Saline for Better Prevention of mUcus pLug in Critical Adult Tracheostomized PatientsWho this might be right forCritical IllnessTracheostomy ComplicationMechanical Ventilation Complication+1 more Hospital Universitario Virgen de la Arrixaca 164
Not applicableEnrolling By InvitationNCT06147453What this trial is testingEffect of OPEP on Mucus Plugging and Airflow Obstruction in Patients with Moderate-to-severe AsthmaWho this might be right forAsthma St. Joseph's Healthcare Hamilton 30
Not applicableLooking for participantsNCT07236541What this trial is testingImpact of Airway Mucus Plugs on Secondary Pulmonary Fibrosis in COPD Patients: A Single-Center Case-Control StudyWho this might be right forLung Fibrosis Ming Zhong 20