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Results for “Muscle Acidosis”

38 trials

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Showing 20 of 38 results

Large-scale testing (Phase 3)Looking for participantsNCT06451757
What this trial is testing

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

Who this might be right for
Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more
Khondrion BV 220
Testing effectiveness (Phase 2)Ended earlyNCT04475549
What this trial is testing

Phase 2a Study of IW-6463 in Adults Diagnosed With Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS)

Who this might be right for
MELAS
Tisento Therapeutics 8
Not applicableLooking for participantsNCT01694940
What this trial is testing

North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)

Who this might be right for
Mitochondrial DisordersMitochondrial Genetic DisordersMitochondrial Diseases+2 more
Columbia University 1,000
Not applicableStudy completedNCT05984186
What this trial is testing

Effect of High Velocity/Hyperoxic Breathing Therapy on Blood Lactate Decline

Who this might be right for
DyspneaLactic AcidosisMuscle+3 more
Vapotherm, Inc. 15
Not applicableStudy completedNCT04098731
What this trial is testing

Evaluation of Respiratory Function in Fibromyalgia

Who this might be right for
FibromyalgiaRespiratory Alkalosis and Metabolic AcidosisChronic Hyperventilation
Uppsala University 90
Not applicableStudy completedNCT05732909
What this trial is testing

The Metabolic Effects of β-hydroxybutyrate on Working Skeletal Muscle

Who this might be right for
AgingMetabolism DisorderKetonemia+1 more
University of Aarhus 25
Testing effectiveness (Phase 2)Study completedNCT04604548
What this trial is testing

The KHENEREXT Study

Who this might be right for
Mitochondrial DiseasesMitochondrial DNA tRNALeu(UUR) m.3243A<G MutationMaternally Inherited Diabetes and Deafness (MIDD)+2 more
Khondrion BV 11
Testing effectiveness (Phase 2)Study completedNCT06644534
What this trial is testing

Assess TTI-0102 vs Placebo in MELAS Patients

Who this might be right for
MELAS SyndromeMitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)
Thiogenesis Therapeutics, Inc. 9
Testing effectiveness (Phase 2)UnknownNCT05398042
What this trial is testing

Ketone Administration During Inactivity and Retraining

Who this might be right for
ExerciseHealthy Male/Female Subjects
KU Leuven 24
Not applicableStudy completedNCT04565444
What this trial is testing

Ketones and Muscle Protein Synthesis

Who this might be right for
KetosisRegulation of Muscle Protein Synthesis
McGill University 36
Large-scale testing (Phase 3)Study completedNCT00509405
What this trial is testing

Effect of Neutralization of Endogenous Acid Production on BMD and Bone Microarchitectural

Who this might be right for
Healthy
Kantonsspital Baselland Bruderholz 202
Not applicableStudy completedNCT04948138
What this trial is testing

Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome

Who this might be right for
MELAS Syndrome
Jesús González de la Aleja Tejera 9
Not applicableNot Yet RecruitingNCT06013397
What this trial is testing

Effectiveness of Ketogenic Diet in MELAS Syndrome

Who this might be right for
MELAS SyndromeKetogenic Dieting
Second Affiliated Hospital, Zhejiang University, School of Medicine 100
Not applicableEnded earlyNCT05165277
What this trial is testing

Effect of Flow Rate and PH on Muscle Acidosis

Who this might be right for
Muscle Acidosis
Taipei Medical University Hospital 14
Testing effectiveness (Phase 2)Study completedNCT00887562
What this trial is testing

Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes

Who this might be right for
MELAS Syndrome
Michio Hirano 27
Not applicableStudy completedNCT00730184
What this trial is testing

Does Potassium Bicarbonate Improve the Effect of Dietary Protein on Bone and Muscle?

Who this might be right for
OsteoporosisSarcopenia
Tufts University 23
Not applicableStudy completedNCT05970094
What this trial is testing

Reduction of Metabolic Acidosis in Patients With Chronic Kidney Disease in Stage 4 and 5

Who this might be right for
Kidney DiseasesMetabolic AcidosisRenal Insufficiency+2 more
University of Copenhagen 20
Testing effectiveness (Phase 2)UnknownNCT00068913
What this trial is testing

Evaluating the Effectiveness of a Dichloroacetate in MELAS Syndrome

Who this might be right for
MELAS Syndrome
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) 35
Not applicableUnknownNCT05255328
What this trial is testing

Clinical Long Term Evaluation of Glutamine Supplement in MELAS Syndrome

Who this might be right for
MELAS Syndrome
Hospital Universitario 12 de Octubre 9
Testing effectiveness (Phase 2)Looking for participantsNCT04984226
What this trial is testing

Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD

Who this might be right for
Chronic Kidney DiseasesMetabolic AcidosisFatigue+4 more
University of California, Davis 80
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