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Results for “Muscular Atrophy, Progressive”

386 trials

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Showing 20 of 386 results

Large-scale testing (Phase 3)Study completedNCT05156320
What this trial is testing

Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam

Who this might be right for
Spinal Muscular AtrophySpinal Muscular Atrophy Type 3Spinal Muscular Atrophy Type 2+7 more
Scholar Rock, Inc. 188
Not applicableUnknownNCT05632666
What this trial is testing

Respiratory Muscle Training in Patients With Spinal Muscular Atrophy (SMA).

Who this might be right for
Spinal Muscular Atrophy
UMC Utrecht 30
Testing effectiveness (Phase 2)Study completedNCT00227266
What this trial is testing

Valproic Acid and Carnitine in Patients With Spinal Muscular Atrophy

Who this might be right for
Spinal Muscular Atrophy
University of Utah 94
Testing effectiveness (Phase 2)Study completedNCT00324454
What this trial is testing

Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease

Who this might be right for
Motor Neuron DiseaseAmyotrophic Lateral SclerosisPrimary Lateral Sclerosis+1 more
Duke University 20
Large-scale testing (Phase 3)Study completedNCT02294461
What this trial is testing

An Asian Study to Evaluate Efficacy and Safety of Oral Enzalutamide in Progressive Metastatic Prostate Cancer Participants

Who this might be right for
Progressive Metastatic Prostate Cancer
Astellas Pharma Inc 395
Early research (Phase 1)Ended earlyNCT05673109
What this trial is testing

AC176 for the Treatment of Metastatic Castration Resistant Prostate Cancer

Who this might be right for
Metastatic Castration Resistant Prostate Cancer
Accutar Biotechnology Inc 8
Not applicableActive Not RecruitingNCT04875416
What this trial is testing

Phenotype, Genotype and Biomarkers 2

Who this might be right for
Amyotrophic Lateral SclerosisHereditary Spastic ParaplegiaPrimary Lateral Sclerosis+2 more
University of Miami 217
Testing effectiveness (Phase 2)Enrolling By InvitationNCT05614531
What this trial is testing

Clinical Trial to Assess the Safety and Efficacy of EXG001-307 in Patients with Spinal Muscular Atrophy Type 1

Who this might be right for
Spinal Muscular Atrophy Type I
Guangzhou Jiayin Biotech Ltd 12
Large-scale testing (Phase 3)Active Not RecruitingNCT04729907
What this trial is testing

Learn About the Long-Term Safety of Higher Doses of Nusinersen (BIIB058) Given as Injections to Participants With Spinal Muscular Atrophy (SMA) Who Took Part in an Earlier Nusinersen Trial (ONWARD)

Who this might be right for
Muscular Atrophy, Spinal
Biogen 115
Not applicableStudy completedNCT01059240
What this trial is testing

SMN Copy Number Distribution in Mali, West Africa

Who this might be right for
Spinal Muscular Atrophy
National Institute of Neurological Disorders and Stroke (NINDS) 701
Not applicableUnknownNCT05157373
What this trial is testing

The Effect of Androgen Receptor Polymorphism on Endometrial Cancer

Who this might be right for
Androgen Receptor AbnormalEndometrial Disorder
University of Nicosia 150
Not applicableUnknownNCT05839145
What this trial is testing

Home Monitoring of Adult Patients With SMA: a Pilot Multicenter Validation Study

Who this might be right for
Muscular Atrophy, Spinal, Type IIMuscular Atrophy, Spinal, Type III
Institut de Myologie, France 60
Testing effectiveness (Phase 2)Looking for participantsNCT06421831
What this trial is testing

Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 3 Patients

Who this might be right for
Spinal Muscular Atrophy Type 3
GeneCradle Inc 21
Testing effectiveness (Phase 2)Looking for participantsNCT05747261
What this trial is testing

Study of the Safety and Efficacy of an Adeno-Associated Viral Vector Carrying the SMN Gene After a Single Intravenous Administration of Escalating Doses in Children With Spinal Muscular Atrophy (BLUEBELL)

Who this might be right for
Spinal Muscular Atrophy (SMA)
Biocad 40
Not applicableStudy completedNCT06648486
What this trial is testing

Robot-assisted Training

Who this might be right for
Spinal Muscular Atrophy (SMA)
Peking University Third Hospital 13
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Testing effectiveness (Phase 2)Looking for participantsNCT07429240
What this trial is testing

PBGENE-DMD Phase 1/2a Safety and Preliminary Efficacy Study in Duchenne Muscular Dystrophy (FUNCTION-DMD)

Who this might be right for
Duchenne Muscular Dystrophy With Mutations Amenable to PBGENE-DMD
Precision BioSciences, Inc. 18
Not applicableStudy completedNCT04335942
What this trial is testing

Characterization of the Postural Habits of Wheelchair Users Analysis of the Acceptability of International Recommendations in the Prevention of Pressure Sores Risk by Using a Connected Textile Sensor

Who this might be right for
Duchenne Muscular DystrophySpinal Muscular Atrophy
Assistance Publique - Hôpitaux de Paris 36
Not applicableLooking for participantsNCT06363357
What this trial is testing

The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder

Who this might be right for
Muscular Dystrophy, DuchenneOrthotic DevicesUpper Extremity+6 more
Seoul National University Hospital 30
Not applicableLooking for participantsNCT06337357
What this trial is testing

Results of Progressive Resistance Training in Older Type 2 Diabetic Patients With Sarcopenia

Who this might be right for
SarcopeniaDiabetes
National Geriatric Hospital 80
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