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Results for “Mutation Abnormality”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT01108107
What this trial is testing

Neoadjuvant Treatment of Colon Cancer

Who this might be right for
Colon Cancer
Vejle Hospital 76
Not applicableStudy completedNCT02369731
What this trial is testing

Registry of Translarna (Ataluren) in Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)

Who this might be right for
Muscular Dystrophy, Duchenne
PTC Therapeutics 316
Testing effectiveness (Phase 2)Looking for participantsNCT03608631
What this trial is testing

IExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation

Who this might be right for
KRAS NP_004976.2:p.G12DMetastatic Pancreatic AdenocarcinomaPancreatic Ductal Adenocarcinoma+1 more
M.D. Anderson Cancer Center 28
Early research (Phase 1)Ended earlyNCT06560645
What this trial is testing

PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation

Who this might be right for
Advanced Solid TumorMetastatic Solid TumorNon-small Cell Lung Carcinoma+7 more
Prelude Therapeutics Incorporated 42
Not applicableStudy completedNCT02751177
What this trial is testing

Detection of KRAS, NRAS et BRAF Mutations in Plasma Circulating DNA From Patients With Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Institut de Cancérologie de Lorraine 236
Not applicableUnknownNCT05748353
What this trial is testing

Endocrine Disruptors and Life STILe in Breast Cancer Development

Who this might be right for
Breast CancerBRCA1 MutationBRCA2 Mutation+3 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 275
Post-approval studies (Phase 4)Ended earlyNCT05183828
What this trial is testing

Effect of HSD3B1 (1245C) Gene Mutation on Treatment of Stage I-III Breast Cancer

Who this might be right for
Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+2 more
University of Washington 62
Testing effectiveness (Phase 2)Study completedNCT01588145
What this trial is testing

Phase I/II Trial to Evaluate Safety, Tolerability and Pharmacokinetic Profile of HM61713 in NSCLC Patients

Who this might be right for
Non Small Cell Lung Cancer
Hanmi Pharmaceutical Company Limited 273
Large-scale testing (Phase 3)Not Yet RecruitingNCT07218575
What this trial is testing

Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations

Who this might be right for
Cowden's DiseaseCowden's SyndromeLhermitte-Duclos Disease+6 more
Boston Children's Hospital 60
Testing effectiveness (Phase 2)Study completedNCT01357161
What this trial is testing

Adavosertib (MK-1775) in Combination With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone for Participants With Platinum-Sensitive Ovarian Tumors With the P53 Gene Mutation (MK-1775-004)

Who this might be right for
Ovarian Cancer
Merck Sharp & Dohme LLC 136
Testing effectiveness (Phase 2)Study completedNCT02311569
What this trial is testing

Sympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation

Who this might be right for
Myeloproliferative NeoplasmPrimary MyelofibrosisEssential Thrombocythemia+1 more
Swiss Cancer Institute 39
Not applicableStudy completedNCT02035046
What this trial is testing

Clinical Significance of Heterozygosity for Mutations of the SLC12A3 Gene Coding for the Thiazide Sensitive Na-Cl Cotransporter

Who this might be right for
Heterozygous Carriers of Gitelman Syndrome
Assistance Publique - Hôpitaux de Paris 250
Testing effectiveness (Phase 2)Study completedNCT04432454
What this trial is testing

Evaluation of Lasofoxifene Combined With Abemaciclib in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

Who this might be right for
Metastatic Breast Cancer
Sermonix Pharmaceuticals Inc. 29
Testing effectiveness (Phase 2)Ended earlyNCT04240002
What this trial is testing

Gilteritinib (ASP2215) Combined With Chemotherapy in Children, Adolescents and Young Adults With FMS-like Tyrosine Kinase 3 (FLT3)/Internal Tandem Duplication (ITD) Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia (AML)Acute Myeloid Leukemia With FMS-like Tyrosine Kinase 3 (FLT3) Mutation / Internal Tandem Duplication (ITD)
Astellas Pharma Global Development, Inc. 9
Not applicableLooking for participantsNCT06408402
What this trial is testing

Impact of Environmental Exposures on Tumor Risk in SDHx-mutation Carriers

Who this might be right for
SDH-Related Familial ParagangliomaSDHx-Related SyndromesSDH Gene Mutation+1 more
Assistance Publique - Hôpitaux de Paris 1,300
Large-scale testing (Phase 3)Looking for participantsNCT06451757
What this trial is testing

KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases

Who this might be right for
Mitochondrial DiseasesMaternally Inherited Diabetes and Deafness (MIDD)Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke-like Episodes (MELAS)+1 more
Khondrion BV 220
Not applicableStudy completedNCT04257045
What this trial is testing

Factors Influencing Cascade Testing Among Women With Hereditary Gynecological Cancers and Their Relatives

Who this might be right for
Breast CarcinomaDeleterious CDH1 Gene MutationDeleterious DICER1 Gene Mutation+6 more
M.D. Anderson Cancer Center 46
Testing effectiveness (Phase 2)Looking for participantsNCT07012031
What this trial is testing

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

Who this might be right for
Locally Advanced Lung Non-Small Cell CarcinomaMetastatic Lung Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8+1 more
National Cancer Institute (NCI) 37
Very early researchLooking for participantsNCT06305962
What this trial is testing

177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors

Who this might be right for
PDL1 Gene MutationNon Small Cell Lung CancerSmall Cell Lung Cancer ( SCLC )+6 more
Radiopharm Theranostics, Ltd 30
Not applicableStudy completedNCT03663647
What this trial is testing

Advanced Melanoma in Russian Experience

Who this might be right for
Cutaneous Melanoma, Stage IVBRAF V600 Mutation
MelanomaPRO, Russia 382
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