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Results for “Myelodysplastic Syndrome With Excess Blasts-2”

22 trials

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Showing 20 of 22 results

Large-scale testing (Phase 3)Active Not RecruitingNCT03839771
What this trial is testing

Ivosidenib or Enasidenib in Combination With Induction Therapy and Consolidation Therapy, Followed by Maintenance Therapy in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myedysplastic Syndrome EB2, With an IDH1 or IDH2 Mutation, Respectively, Eligible for Intensive Chemotherapy

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome With Excess Blasts-2
Stichting Hemato-Oncologie voor Volwassenen Nederland 968
Early research (Phase 1)Study completedNCT00278330
What this trial is testing

Flavopiridol and Vorinostat in Treating Patients With Relapsed or Refractory Acute Leukemia or Chronic Myelogenous Leukemia or Refractory Anemia

Who this might be right for
Blastic Phase Chronic Myelogenous LeukemiaRecurrent Adult Acute Lymphoblastic LeukemiaRecurrent Adult Acute Myeloid Leukemia+4 more
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Study completedNCT03338348
What this trial is testing

Study of Vosaroxin With Azacitidine in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndrome With Excess Blasts-2

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome With Excess Blasts-2 (MDS-EB-2)
University of Ulm 9
Testing effectiveness (Phase 2)Study completedNCT01858740
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts in Preventing GVHD in Children

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+15 more
Fred Hutchinson Cancer Center 20
Large-scale testing (Phase 3)Study completedNCT02744742
What this trial is testing

G-CSF+Decitabine+BUCY vs BUCY Conditioning Regimen for RAEB-1, REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT

Who this might be right for
Myelodysplastic SyndromeAllogeneic Hematopoietic Stem Cell TransplantationConditioning
Nanfang Hospital, Southern Medical University 202
Not applicableUnknownNCT02850822
What this trial is testing

Effect of Chemotherapy vs No Chemotherapy Pre-transplant to MDS Undergoing Allo-HSCT

Who this might be right for
Myelodysplastic SyndromeChemotherapy
Nanfang Hospital, Southern Medical University 250
Testing effectiveness (Phase 2)Ended earlyNCT04526288
What this trial is testing

CPX-351 Versus Immediate Stem Cell Transplantation for the Treatment of High-Grade Myeloid Cancers With Measurable Residual Disease

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome With Excess Blasts-2Myeloid Neoplasm
Fred Hutchinson Cancer Center 1
Early research (Phase 1)Active Not RecruitingNCT02530034
What this trial is testing

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveHematopoietic and Lymphoid Cell Neoplasm+8 more
M.D. Anderson Cancer Center 72
Not applicableStudy completedNCT00426205
What this trial is testing

GM-CSF Vaccinations After Allogeneic Blood Stem Cell Transplantation in Patients With Advanced Myeloid Malignancies

Who this might be right for
Myelodysplastic Syndrome RAEB-I or RAEB-IIRefractory Acute Myeloid LeukemiaRefractory CML Myeloid Blast Crisis
Dana-Farber Cancer Institute 28
Large-scale testing (Phase 3)Active Not RecruitingNCT04027309
What this trial is testing

Gilteritinib Versus Midostaurin in Combination With Induction and Consolidation Therapy Followed by One-year Maintenance in Patients With Newly Diagnosed Acute Myeloid Leukemia or Myelodysplastic Syndromes With Excess Blasts-2 With FLT3 Mutations Eligible for Intensive Chemotherapy

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome With Excess Blasts-2
Stichting Hemato-Oncologie voor Volwassenen Nederland 777
Testing effectiveness (Phase 2)Study completedNCT01012492
What this trial is testing

Pilot of Abatacept-based Immunosuppression for Prevention of Acute GvHD During Unrelated Donor HCT

Who this might be right for
AMLALLUndifferentiated Leukemia+9 more
Boston Children's Hospital 11
Testing effectiveness (Phase 2)Study completedNCT02220985
What this trial is testing

Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia of Ambiguous Lineage+20 more
Fred Hutchinson Cancer Center 84
Early research (Phase 1)Looking for participantsNCT05703542
What this trial is testing

BXCL701 Phase 1 R/R Acute Myeloid Leukemia or Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome With Excess Blasts-2
Eric Stephen Winer, MD 24
Large-scale testing (Phase 3)Looking for participantsNCT04628026
What this trial is testing

Phase III Study of Induction and Consolidation Chemotherapy With Venetoclax in Patients With Newly Diagnosed AML or MDS-EB-2

Who this might be right for
Acute Myeloid Leukemia
University of Ulm 650
Early research (Phase 1)UnknownNCT02493829
What this trial is testing

B7.1/IL-2 Leukaemia Cell Vaccine for Non-Transplant AML RFUSIN2-AML2 (NTX)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
King's College London 10
Large-scale testing (Phase 3)UnknownNCT04713956
What this trial is testing

G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for RAEB-1,REAB-2 and AML Secondary to MDS Undergoing Allo-HSCT

Who this might be right for
Myelodysplastic SyndromeAllogeneic Hematopoietic Stem Cell TransplantationConditioning
Nanfang Hospital, Southern Medical University 242
Early research (Phase 1)Study completedNCT00533416
What this trial is testing

Safety of ON 01910.Na in Patients With Myelodysplasia

Who this might be right for
Myelodysplastic Syndrome (MDS)
National Heart, Lung, and Blood Institute (NHLBI) 14
Testing effectiveness (Phase 2)Looking for participantsNCT03850574
What this trial is testing

Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia

Who this might be right for
Leukemia, Myeloid, AcuteRefractory AMLRelapsed Adult AML+2 more
Aptose Biosciences Inc. 240
Early research (Phase 1)Study completedNCT01139151
What this trial is testing

4'-Thio-araC (Thiarabine) in Advanced Hematologic Malignancies

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 31
Testing effectiveness (Phase 2)UnknownNCT06247917
What this trial is testing

Evaluate the Efficacy and Safety of Allogeneic Haematopoietic Stem Cell Transplantation With FBM Conditioning for MDS

Who this might be right for
Myelodysplastic Syndrome With Excess Blasts-1Myelodysplastic Syndrome With Excess Blasts-2Myelodysplastic Syndromes
Ruijin Hospital 59
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