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Results for “Myotonic Dystrophy 1”

208 trials

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Showing 20 of 208 results

Testing effectiveness (Phase 2)Looking for participantsNCT06185764
What this trial is testing

VX-670 in Adult Participants With Myotonic Dystrophy 1 (DM1)

Who this might be right for
Myotonic Dystrophy Type 1 (DM1)
Vertex Pharmaceuticals Incorporated 36
Not applicableLooking for participantsNCT06747884
What this trial is testing

Trial Readiness and Endpoint Assessment in Pediatric Myotonic Dystrophy Extension

Who this might be right for
Congenital Myotonic DystrophyChildhood Myotonic DystrophyMyotonic Dystrophy
Virginia Commonwealth University 200
Not applicableEnded earlyNCT02930408
What this trial is testing

Compare Train and 3D-4D Left Ventricular Systolic Function in Subjects Suffering From Dystrophy and Healthy Subjects

Who this might be right for
Steinert's Disease
Poitiers University Hospital 70
Large-scale testing (Phase 3)Active Not RecruitingNCT03529110
What this trial is testing

DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metastatic Breast Cancer Previously Treated With Trastuzumab and Taxane [DESTINY-Breast03]

Who this might be right for
Breast Cancer
Daiichi Sankyo 524
Testing effectiveness (Phase 2)Study completedNCT02312011
What this trial is testing

A Safety andTolerability Study of Multiple Doses of ISIS-DMPKRx in Adults With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy Type 1
Ionis Pharmaceuticals, Inc. 48
Not applicableUnknownNCT03784586
What this trial is testing

Sudden Cardiac Death Stratification in Myotonic Dystrophy Type 1 Patients

Who this might be right for
Myotonic Dystrophy 1Sudden Cardiac Death
University of Campania Luigi Vanvitelli 70
Large-scale testing (Phase 3)Active Not RecruitingNCT04622319
What this trial is testing

Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Participants With Residual Invasive Breast Cancer Following Neoadjuvant Therapy (DESTINY-Breast05)

Who this might be right for
HER2-Positive Primary Breast CancerResidual Invasive Breast Cancer
Daiichi Sankyo 1,600
Not applicableUnknownNCT05231863
What this trial is testing

Tyrosine Kinase Inhibitors (TKIs) in Trastuzumab Emtansine (T-DM1) Resistant HER2-positive Metastatic Breast Cancer: A Real-world Study

Who this might be right for
Breast Cancer
The First Affiliated Hospital with Nanjing Medical University 100
Testing effectiveness (Phase 2)Looking for participantsNCT06667453
What this trial is testing

A Clinical Study of PGN-EDODM1 in People With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy 1
PepGen Inc 24
Not applicableActive Not RecruitingNCT04616807
What this trial is testing

An Observational Study in Adult Patients With Non-dystrophic Myotonic Disorders

Who this might be right for
Myotonic Dystrophy
Lupin Ltd. 53
Early research (Phase 1)Study completedNCT00932373
What this trial is testing

Trastuzumab-MCC-DM1 Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer Who Have Previously Received a Trastuzumab-Containing Regimen

Who this might be right for
Metastatic Breast Cancer
Genentech, Inc. 54
Not applicableStudy completedNCT03087526
What this trial is testing

NIPD on CFTC for Triplet Repeat Diseases

Who this might be right for
Non Invasive Prenatal Diagnosis
University Hospital, Montpellier 60
Early research (Phase 1)Study completedNCT00928330
What this trial is testing

Trastuzumab and Trastuzumab-MCC-DM1 Administered Intravenously and GDC-0941 Administered Orally to Patients With HER2-Positive Metastatic Breast Cancer Who Have Progressed on Previous Trastuzumab-Based Therapy

Who this might be right for
Metastatic Breast Cancer
Genentech, Inc. 57
Large-scale testing (Phase 3)Looking for participantsNCT06523400
What this trial is testing

The Efficacy and Safety of Once Daily Mexiletine PR in Patients With Myotonic Dystrophy Type 1 and Type 2

Who this might be right for
Myotonic Dystrophy
Lupin Ltd. 176
Testing effectiveness (Phase 2)Looking for participantsNCT04893109
What this trial is testing

ATEMPT 2.0: Adjuvant T-DM1 vs TH

Who this might be right for
Breast CancerHER2-positive Breast Cancer
Dana-Farber Cancer Institute 500
Testing effectiveness (Phase 2)Ended earlyNCT03190967
What this trial is testing

T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery

Who this might be right for
Breast CancerBrain MetastasisBrain Cancer
National Cancer Institute (NCI) 12
Early research (Phase 1)Study completedNCT02073916
What this trial is testing

T-DM1 With Abraxane and Lapatinib for Metastatic HER2 Positive Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Jenny C. Chang, MD 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03587740
What this trial is testing

ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer

Who this might be right for
Breast Cancer
Dana-Farber Cancer Institute 82
Not applicableStudy completedNCT03589677
What this trial is testing

Brain Involvement in Myotonic Dystrophy Type I: From Functional Neuroimaging to the Impact on Quality of Life

Who this might be right for
Myotonic Dystrophy Type 1 (DM1)
IRCCS San Camillo, Venezia, Italy 50
Not applicableLooking for participantsNCT04003363
What this trial is testing

The United Kingdom National Registry for Myotonic Dystrophy

Who this might be right for
Myotonic Dystrophy
Newcastle University 900
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