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Results for “Myotonic Dystrophy 1”

218 trials

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Showing 20 of 218 results

Large-scale testing (Phase 3)Looking for participantsNCT05532813
What this trial is testing

Evaluation of the Efficacy and Safety of Metformin in the Myotonic Dystrophy Type 1 (Steinert's Disease)

Who this might be right for
Steinert's DiseaseMyotonic Dystrophy 1Metformin
Assistance Publique - Hôpitaux de Paris 142
Testing effectiveness (Phase 2)Study completedNCT00951665
What this trial is testing

Trastuzumab Emtansine, Paclitaxel, and Pertuzumab in Patients With HER2-Positive, Locally Advanced or Metastatic Breast Cancer

Who this might be right for
Metastatic Breast Cancer
Genentech, Inc. 107
Not applicableEnrolling By InvitationNCT06605612
What this trial is testing

Development and Validation of the FBIndex to Determine the Risk of Falls for Patients With Neuromuscular Disorders

Who this might be right for
Inclusion Body MyositisMyotonic DystrophyLimb-girdle and Facioscapulohumeral Muscular Dystrophies+9 more
LMU Klinikum 108
Not applicableNot Yet RecruitingNCT07732439
What this trial is testing

An Ambispective Natural History Study in Myotonic Dystrophy Patients Linking Retrospective Data Captured From the DM-Scope Registry With a Prospective 24-month Follow-up Period

Who this might be right for
Myotonic Dystrophy 1Myotonic Dystrophy 2
Lupin Ltd. 100
Not applicableStudy completedNCT04616807
What this trial is testing

An Observational Study in Adult Patients With Non-dystrophic Myotonic Disorders

Who this might be right for
Myotonic Dystrophy
Lupin Ltd. 53
Not applicableLooking for participantsNCT06716931
What this trial is testing

Investigating Exercise in Myotonic Dystrophy Type 2 (DM2)

Who this might be right for
Myotonic Dystrophy 2
Massachusetts General Hospital 24
Not applicableStudy completedNCT05945927
What this trial is testing

Evaluate the Safety and Effectiveness of Trastuzumab Emtansine (T-DM1) as Therapy in Chinese Participants With HER2 Positive Advanced Breast Cancer

Who this might be right for
Breast Cancer
Hoffmann-La Roche 178
Not applicableStudy completedNCT01242007
What this trial is testing

Postural Spirometry Changes in Ambulatory Myotonic Dystrophy Patients

Who this might be right for
Myotonic Dystrophy
University of Nancy 58
Large-scale testing (Phase 3)Study completedNCT01421992
What this trial is testing

Methylphenidate in Myotonic Dystrophy Type 1

Who this might be right for
Dystrophia Myotonica 1
Laval University 28
Not applicableLooking for participantsNCT06693037
What this trial is testing

Adjuvant Therapy Choice for Non-pCR HER2 Positive Early Breast Cancer After Neoadjuvant Therapy

Who this might be right for
HER2-positive Breast Cancer
Shu Wang 2,092
Early research (Phase 1)Study completedNCT00932373
What this trial is testing

Trastuzumab-MCC-DM1 Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer Who Have Previously Received a Trastuzumab-Containing Regimen

Who this might be right for
Metastatic Breast Cancer
Genentech, Inc. 54
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06481956
What this trial is testing

T-DM1 Combined With CDK4/6 Inhibitor Ribociclib

Who this might be right for
HER2-positive Advanced Breast Cancer
Zheng Yabing 40
Testing effectiveness (Phase 2)Study completedNCT00943670
What this trial is testing

Corrected QT Interval Effects of Trastuzumab Emtansine (T-DM1) in Patients With Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Locally Advanced or Metastatic Breast Cancer and the Safety and Tolerability of Combined T-DM1 and Pertuzumab in Patients With Early Disease Progression

Who this might be right for
Metastatic Breast Cancer
Genentech, Inc. 51
Testing effectiveness (Phase 2)Looking for participantsNCT06138743
What this trial is testing

Study of SRP-1003 in Participants With Type 1 Myotonic Dystrophy

Who this might be right for
Myotonic Dystrophy 1
Sarepta Therapeutics, Inc. 78
Early research (Phase 1)Ended earlyNCT04042051
What this trial is testing

Copanlisib in Combination With T-DM1 in Pretreated Unresectable Locally Advanced or Metastatic HER2-positive Breast Cancer

Who this might be right for
HER2-positive Breast CancerMetastatic Breast CancerLocally Advanced Breast Cancer+1 more
Cancer Trials Ireland 2
Not applicableStudy completedNCT05400629
What this trial is testing

Effects of a 12-week Strength Training Program in Women With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy 1
Université de Sherbrooke 12
Not applicableUnknownNCT05560308
What this trial is testing

Phase II Clinical Study of T-DM1 and Pyrotinib Maleate in Patients With HER2-positive Metastatic Breast Cancer Who Had Progressed on TKI Therapy

Who this might be right for
HER2+ Advanced Breast Cancer Patients Progressing on TKI Therapy
Tianjin Medical University Cancer Institute and Hospital 50
Testing effectiveness (Phase 2)Study completedNCT04886518
What this trial is testing

Safety and Efficacy of Pitolisant on Excessive Daytime Sleepiness and Other Non-Muscular Symptoms in Patients With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy 1Excessive Daytime Sleepiness
Harmony Biosciences Management, Inc. 30
Early research (Phase 1)Study completedNCT06204809
What this trial is testing

Safety, Tolerability, PK, and PD Study of PGN-EDODM1 in Participants With Myotonic Dystrophy Type 1

Who this might be right for
Myotonic Dystrophy 1
PepGen Inc 24
Testing effectiveness (Phase 2)Looking for participantsNCT04620187
What this trial is testing

Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

Who this might be right for
Salivary Gland CancerHER2 Gene Mutation
Dana-Farber Cancer Institute 37
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