Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “NLRP3”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Ended earlyNCT04540120
What this trial is testing

Safety and Efficacy of Dapansutrile for Treatment of Moderate COVID-19 Symptoms and Evidence of Early Cytokine Release Syndrome

Who this might be right for
Covid19Cytokine Release Syndrome
Olatec Therapeutics, Inc. 49
Not applicableLooking for participantsNCT06657781
What this trial is testing

Study and Role of Inflammasome in Platelet Activation During Bacterial And/or Viral Sepsis

Who this might be right for
Bacterial Sepsis
Centre Hospitalier Universitaire de la Guadeloupe 171
Not applicableStudy completedNCT02326376
What this trial is testing

Kineret CAPS Post Authorisation Study

Who this might be right for
Cryopyrin-Associated Periodic Syndromes
Swedish Orphan Biovitrum 12
Testing effectiveness (Phase 2)Study completedNCT07220629
What this trial is testing

Study to Explore the Safety and Efficacy of NT-0796 as an Adjunct to Semaglutide in Participants With Obesity (RESOLVE-2)

Who this might be right for
Obesity
Rezera (formerly NodThera Limited) 82
Not applicableStudy completedNCT04191642
What this trial is testing

Correlation of NLRP3 With Cognitive Dysfunction Early After Heart Valve Replacement Surgery

Who this might be right for
InflammasomesCognitive DysfunctionPyrin Domain-Containing 3 Protein+1 more
General Hospital of Ningxia Medical University 75
Testing effectiveness (Phase 2)WithdrawnNCT05330013
What this trial is testing

The Effect of Inflammation in Heart Failure

Who this might be right for
Myocardial DysfunctionHeart FailureInflammation
National Heart, Lung, and Blood Institute (NHLBI)
Testing effectiveness (Phase 2)Looking for participantsNCT06047262
What this trial is testing

Dapansutrile in Diabetes and Diabetes-Related Complications - Dapan-Dia

Who this might be right for
Diabetes Mellitus, Type 2
Marc Donath 300
Large-scale testing (Phase 3)Ended earlyNCT00770601
What this trial is testing

Canakinumab to Treat Neonatal-Onset Multisystem Inflammatory Disease

Who this might be right for
NOMIDCINCA Syndrome
Novartis Pharmaceuticals 7
Testing effectiveness (Phase 2)Study completedNCT07370220
What this trial is testing

Effect of Rutin on Inflammation Pathways in Ulcerative Colitis Patients

Who this might be right for
Ulcerative Colitis
Benha University 60
Testing effectiveness (Phase 2)Study completedNCT07055516
What this trial is testing

Evaluate the Efficacy and Safety of NT-0796 in Participants With Obesity With or Without Type 2 Diabetes Mellitus

Who this might be right for
Obesity and Type 2 Diabetes
Rezera (formerly NodThera Limited) 176
Not applicableNot Yet RecruitingNCT05292768
What this trial is testing

Are Mast Cells Involved in Autoinflammatory Diseases

Who this might be right for
Autoinflammatory DiseaseFMFTRAPS+3 more
Assistance Publique - Hôpitaux de Paris 590
Early research (Phase 1)Study completedNCT04015076
What this trial is testing

Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With Inzomelid

Who this might be right for
Healthy
Inflazome UK Ltd 80
Testing effectiveness (Phase 2)Ended earlyNCT00069329
What this trial is testing

Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease

Who this might be right for
Nervous System MalformationsArthropathy, NeurogenicUrticaria+1 more
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) 43
Not applicableWithdrawnNCT06200441
What this trial is testing

Correlation of Serum Gasdermin-D and NLRP-3 Inflammasome Levels With GVHD Biomarkers and Endothelial Damage Markers in Graft-Versus-Host Disease

Who this might be right for
Acute Myeloid Leukemia, AdultGraft Versus Host DiseaseEndothelial Dysfunction
Ugur Arzu Kulu
Early research (Phase 1)Looking for participantsNCT07463196
What this trial is testing

A Study Investigating the Safety, Absorption, Elimination, and the Effect on the Immune System of ACI-19764 in Healthy Participants and in Participants With Cardiovascular Risk Factors

Who this might be right for
Healthy ParticipantsObesityType 2 Diabetes Mellitus (T2DM)
AC Immune SA 114
Not applicableStudy completedNCT07147842
What this trial is testing

Rutin Therapy Role in Reducing Ulcerative Colitis Severity

Who this might be right for
Ulcerative Colitis
Benha University 60
Large-scale testing (Phase 3)Study completedNCT00991146
What this trial is testing

Efficacy and Safety Study of Canakinumab Administered for 6 Months (24 Weeks) in Japanese Patients With Cryopyrin-associated Periodic Syndromes Followed by an Extension Phase

Who this might be right for
Cryopyrin-associated Periodic SyndromesFamilial Cold Autoinflammatory SyndromeMuckle-Wells Syndrome+1 more
Novartis Pharmaceuticals 19
Not applicableLooking for participantsNCT04485871
What this trial is testing

Targeting Risk Factors for Diabetes in Subjects With Normal Blood Cholesterol Using Omega-3 Fatty Acids

Who this might be right for
Type 2 DiabetesInflammationInsulin Sensitivity/Resistance+1 more
Institut de Recherches Cliniques de Montreal 48
Post-approval studies (Phase 4)Study completedNCT05896605
What this trial is testing

Monitoring of Azathioprine Metabolite Concentrations and Cytokine Levels in Neuromyelitis Optica Spectrum Disorder

Who this might be right for
NMO Spectrum DisorderAzathioprine Adverse Reaction
First Affiliated Hospital of Guangxi Medical University 63
Not applicableUnknownNCT04409522
What this trial is testing

Evaluation of Therapeutic Effects of Melatonin by Inhibition of NLRP3 Inflammasome in COVID19 Patients

Who this might be right for
COVID-19
Mohammad Sadegh Bagheri Baghdasht 55
Next Page