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Results for “NTRK Fusion Positive”

29 trials

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Showing 20 of 29 results

Early research (Phase 1)Ended earlyNCT01804530
What this trial is testing

Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors

Who this might be right for
Solid TumorTumors of Any Histology With Activating Trk (NTRK) Point or NTRK Fusion MutationsTenosynovial Giant Cell Tumor
Plexxikon 59
Testing effectiveness (Phase 2)Looking for participantsNCT01639508
What this trial is testing

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

Who this might be right for
Non-Small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center 86
Early research (Phase 1)Ended earlyNCT03182257
What this trial is testing

Study of ONO-7579 in Patients With Advanced Solid Tumors/ NTRK Gene Fusion Positive Advanced Solid Tumors

Who this might be right for
Solid Tumor
Ono Pharmaceutical Co., Ltd. 1
Not applicableLooking for participantsNCT04945330
What this trial is testing

NTRK Gene Fusion - Positive Advanced or Recurrent Solid Tumors, a Rare Cancer Caused by Specific Changes in the Genes

Who this might be right for
Advanced or Recurrent Solid Tumor Harboring an NTRK Gene Fusion
Bayer 100
Not applicableStudy completedNCT06837090
What this trial is testing

Retrospective Analysis of the Experience With Larotrectinib in Patients With Solid Neoplasms With NTRK Fusion in Spain (SPAINTRK)

Who this might be right for
Solid Neoplasms With NTRK Fusions
Grupo Espanol de Tumores Neuroendocrinos 20
Not applicableNo Longer AvailableNCT03206931
What this trial is testing

Expanded Access to Provide Selitrectinib for the Treatment of Cancers With a NTRK Gene Fusion

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer
Not applicableStudy completedNCT05192642
What this trial is testing

A Study Called VICTORIA to Learn More About How Well Larotrectinib Works in Adults With TRK Fusion-positive Cancer by Comparing Larotrectinib Data From Clinical Studies With Data of Other Treatments From Actual Practice

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 368
Testing effectiveness (Phase 2)Looking for participantsNCT04996121
What this trial is testing

XZP-5955 Tablets in Patients With NTRK or ROS1 Fusion Positive Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid TumorsLocally Advanced or Metastatic Non-small Cell Lung Cancer
Xuanzhu Biopharmaceutical Co., Ltd. 360
Testing effectiveness (Phase 2)Looking for participantsNCT07394374
What this trial is testing

CG001419 Tablets in Adult Subjects With Locally Advanced or Metastatic Solid Tumours Harbouring NTRK Gene Abnormalities

Who this might be right for
Solid Tumors Harboring NTRK FusionNTRKNTRK Gene Fusion+1 more
Cullgen (Shanghai),Inc 42
Early research (Phase 1)Study completedNCT02675491
What this trial is testing

Phase 1 Study of DS-6051b in Japanese Subjects With Advanced Solid Malignant Tumors

Who this might be right for
Advanced Solid Malignant Tumors
Daiichi Sankyo Co., Ltd. 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT03834961
What this trial is testing

Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia

Who this might be right for
Central Nervous System NeoplasmInfantile FibrosarcomaRecurrent Acute Leukemia+2 more
Children's Oncology Group 33
Testing effectiveness (Phase 2)Looking for participantsNCT06239272
What this trial is testing

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

Who this might be right for
Adipocytic NeoplasmLiposarcomaAtypical Fibroxanthoma+6 more
St. Jude Children's Research Hospital 139
Testing effectiveness (Phase 2)Looking for participantsNCT05745623
What this trial is testing

Study of ICP-723 in Patients With Advanced Solid Tumors or Primary Central Nervous System Tumors

Who this might be right for
Advanced Solid Tumors Harboring NTRK FusionPrimary Central Nervous System Tumors Harboring NTRK Fusion
Beijing InnoCare Pharma Tech Co., Ltd. 70
Early research (Phase 1)Ended earlyNCT04901806
What this trial is testing

Study of PBI-200 in Subjects With NTRK-Fusion-Positive Solid Tumors

Who this might be right for
Solid Tumor, AdultBrain Tumor, PrimaryDesmoplastic Small Round Cell Tumor
Pyramid Biosciences 29
Not applicableStudy completedNCT05796258
What this trial is testing

Three-pronged Centralized Molecular Analysis to Optimize Detection of NTRK1,2,3 Fusions in Thyroid Cancer

Who this might be right for
Thyroid Cancer
Regina Elena Cancer Institute 100
Early research (Phase 1)UnknownNCT04687423
What this trial is testing

Study of FCN-011 in Patients With Advanced Solid Tumor（Phase I）and NTRK Fusion Positive Advanced Solid Tumor （Phase II）

Who this might be right for
Advanced Solid Tumor
Fochon Pharmaceuticals, Ltd. 82
Very early researchLooking for participantsNCT04655404
What this trial is testing

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine Glioma
Nationwide Children's Hospital 15
Early research (Phase 1)Study completedNCT02122913
What this trial is testing

Test the Safety of the Investigational Drug Larotrectinib in Adults That May Treat Cancer

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 75
Not applicableUnknownNCT04921553
What this trial is testing

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING)

Who this might be right for
CancerCancer MetastaticNTRK Gene Fusion Overexpression+13 more
Centre Leon Berard 500
Testing effectiveness (Phase 2)Study completedNCT02576431
What this trial is testing

Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 215
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