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Results for “NTRK Fusion Positive”

30 trials

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Showing 20 of 30 results

Early research (Phase 1)Study completedNCT02675491
What this trial is testing

Phase 1 Study of DS-6051b in Japanese Subjects With Advanced Solid Malignant Tumors

Who this might be right for
Advanced Solid Malignant Tumors
Daiichi Sankyo Co., Ltd. 15
Not applicableNot Yet RecruitingNCT07599007
What this trial is testing

Repotrectinib Post-Marketing Surveillance in Korean Patients With ROS1-Positive Non-Small Cell Lung Cancer (NSCLC) or Solid Tumors Harboring a Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusion

Who this might be right for
Non-Small Cell Lung Cancer
Bristol-Myers Squibb 10
Early research (Phase 1)Study completedNCT04275960
What this trial is testing

Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 24
Testing effectiveness (Phase 2)Looking for participantsNCT06239272
What this trial is testing

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

Who this might be right for
Adipocytic NeoplasmLiposarcomaAtypical Fibroxanthoma+6 more
St. Jude Children's Research Hospital 139
Early research (Phase 1)UnknownNCT04687423
What this trial is testing

Study of FCN-011 in Patients With Advanced Solid Tumor（Phase I）and NTRK Fusion Positive Advanced Solid Tumor （Phase II）

Who this might be right for
Advanced Solid Tumor
Fochon Pharmaceuticals, Ltd. 82
Early research (Phase 1)Study completedNCT04771390
What this trial is testing

Study to Compare How the Body Absorbs, Distributes and Excretes the Drug Selitrectinib (BAY2731954) Given as Two Different Tablet Formulations or as Liquid Formulations Including the Effect of Food on the Absorption, Distribution or Excretion of the Different Formulations in Healthy Participants

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 52
Not applicableStudy completedNCT04557813
What this trial is testing

Registry for Molecular Testing, Treatment and Outcome of Patients With Solid Tumors Harboring a NTRK Gene Fusion

Who this might be right for
NTRK Family Gene Mutation
iOMEDICO AG 88
Testing effectiveness (Phase 2)Looking for participantsNCT05745623
What this trial is testing

Study of ICP-723 in Patients With Advanced Solid Tumors or Primary Central Nervous System Tumors

Who this might be right for
Advanced Solid Tumors Harboring NTRK FusionPrimary Central Nervous System Tumors Harboring NTRK Fusion
Beijing InnoCare Pharma Tech Co., Ltd. 70
Not applicableStudy completedNCT05793281
What this trial is testing

An Observational Study to Learn More About NTRK Gene Fusion Positive in Solid Tumor in Japan

Who this might be right for
Advanced or Recurrent Solid Tumor Harboring an NTRK Gene Fusion
Bayer 46,621
Testing effectiveness (Phase 2)Active Not RecruitingNCT02637687
What this trial is testing

Test the Safety and Efficacy of the Drug Larotrectinib for the Treatment of Tumors With NTRK-fusion in Children

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 154
Not applicableNo Longer AvailableNCT03206931
What this trial is testing

Expanded Access to Provide Selitrectinib for the Treatment of Cancers With a NTRK Gene Fusion

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer
Very early researchLooking for participantsNCT04655404
What this trial is testing

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine Glioma
Nationwide Children's Hospital 15
Not applicableStudy completedNCT05796258
What this trial is testing

Three-pronged Centralized Molecular Analysis to Optimize Detection of NTRK1,2,3 Fusions in Thyroid Cancer

Who this might be right for
Thyroid Cancer
Regina Elena Cancer Institute 100
Not applicableApproved For MarketingNCT03025360
What this trial is testing

Expanded Access to Provide Larotrectinib for the Treatment of Cancers With a NTRK Gene Fusion

Who this might be right for
Tumors Harboring NTRK Fusion
Bayer
Not applicableUnknownNCT04921553
What this trial is testing

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING)

Who this might be right for
CancerCancer MetastaticNTRK Gene Fusion Overexpression+13 more
Centre Leon Berard 500
Not applicableStudy completedNCT05236257
What this trial is testing

A Study Called EPI VITRAKVI to Compare Treatment Results in Patients With Infantile Fibrosarcoma (IFS), a Type of Connective Soft Tissue Cancer, Who Received a Treatment Called Larotrectinib From a Study Called SCOUT With Patient Data From an External Database

Who this might be right for
Locally Advanced or Metastatic Infantile Fibrosarcoma Harboring an NTRK Gene FusionInfantile Fibrosarcoma
Bayer 93
Testing effectiveness (Phase 2)Looking for participantsNCT01639508
What this trial is testing

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

Who this might be right for
Non-Small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center 86
Testing effectiveness (Phase 2)Looking for participantsNCT04996121
What this trial is testing

XZP-5955 Tablets in Patients With NTRK or ROS1 Fusion Positive Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Locally Advanced or Metastatic Solid TumorsLocally Advanced or Metastatic Non-small Cell Lung Cancer
Xuanzhu Biopharmaceutical Co., Ltd. 360
Testing effectiveness (Phase 2)Looking for participantsNCT07394374
What this trial is testing

CG001419 Tablets in Adult Subjects With Locally Advanced or Metastatic Solid Tumours Harbouring NTRK Gene Abnormalities

Who this might be right for
Solid Tumors Harboring NTRK FusionNTRKNTRK Gene Fusion+1 more
Cullgen (Shanghai),Inc 42
Not applicableStudy completedNCT06837090
What this trial is testing

Retrospective Analysis of the Experience With Larotrectinib in Patients With Solid Neoplasms With NTRK Fusion in Spain (SPAINTRK)

Who this might be right for
Solid Neoplasms With NTRK Fusions
Grupo Espanol de Tumores Neuroendocrinos 20
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