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Results for “NTRK Fusion Positive”

30 trials

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Showing 20 of 30 results

Early research (Phase 1)Study completedNCT04275960
What this trial is testing

Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 24
Not applicableLooking for participantsNCT04945330
What this trial is testing

NTRK Gene Fusion - Positive Advanced or Recurrent Solid Tumors, a Rare Cancer Caused by Specific Changes in the Genes

Who this might be right for
Advanced or Recurrent Solid Tumor Harboring an NTRK Gene Fusion
Bayer 100
Early research (Phase 1)Ended earlyNCT01804530
What this trial is testing

Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors

Who this might be right for
Solid TumorTumors of Any Histology With Activating Trk (NTRK) Point or NTRK Fusion MutationsTenosynovial Giant Cell Tumor
Plexxikon 59
Testing effectiveness (Phase 2)Active Not RecruitingNCT03834961
What this trial is testing

Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia

Who this might be right for
Central Nervous System NeoplasmInfantile FibrosarcomaRecurrent Acute Leukemia+2 more
Children's Oncology Group 33
Testing effectiveness (Phase 2)Active Not RecruitingNCT03944772
What this trial is testing

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Who this might be right for
Non-Small Cell Lung Cancer
AstraZeneca 247
Not applicableStudy completedNCT05796258
What this trial is testing

Three-pronged Centralized Molecular Analysis to Optimize Detection of NTRK1,2,3 Fusions in Thyroid Cancer

Who this might be right for
Thyroid Cancer
Regina Elena Cancer Institute 100
Not applicableStudy completedNCT04557813
What this trial is testing

Registry for Molecular Testing, Treatment and Outcome of Patients With Solid Tumors Harboring a NTRK Gene Fusion

Who this might be right for
NTRK Family Gene Mutation
iOMEDICO AG 88
Testing effectiveness (Phase 2)Looking for participantsNCT07394374
What this trial is testing

CG001419 Tablets in Adult Subjects With Locally Advanced or Metastatic Solid Tumours Harbouring NTRK Gene Abnormalities

Who this might be right for
Solid Tumors Harboring NTRK FusionNTRKNTRK Gene Fusion+1 more
Cullgen (Shanghai),Inc 42
Not applicableStudy completedNCT05192642
What this trial is testing

A Study Called VICTORIA to Learn More About How Well Larotrectinib Works in Adults With TRK Fusion-positive Cancer by Comparing Larotrectinib Data From Clinical Studies With Data of Other Treatments From Actual Practice

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 368
Early research (Phase 1)Study completedNCT04771390
What this trial is testing

Study to Compare How the Body Absorbs, Distributes and Excretes the Drug Selitrectinib (BAY2731954) Given as Two Different Tablet Formulations or as Liquid Formulations Including the Effect of Food on the Absorption, Distribution or Excretion of the Different Formulations in Healthy Participants

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 52
Testing effectiveness (Phase 2)Looking for participantsNCT01639508
What this trial is testing

Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity

Who this might be right for
Non-Small Cell Lung Cancer
Memorial Sloan Kettering Cancer Center 86
Testing effectiveness (Phase 2)Study completedNCT02576431
What this trial is testing

Test the Effect of the Drug Larotrectinib in Adults and Children With NTRK-fusion Positive Solid Tumors

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 215
Early research (Phase 1)UnknownNCT04687423
What this trial is testing

Study of FCN-011 in Patients With Advanced Solid Tumor（Phase I）and NTRK Fusion Positive Advanced Solid Tumor （Phase II）

Who this might be right for
Advanced Solid Tumor
Fochon Pharmaceuticals, Ltd. 82
Very early researchLooking for participantsNCT04655404
What this trial is testing

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine Glioma
Nationwide Children's Hospital 15
Not applicableStudy completedNCT05236257
What this trial is testing

A Study Called EPI VITRAKVI to Compare Treatment Results in Patients With Infantile Fibrosarcoma (IFS), a Type of Connective Soft Tissue Cancer, Who Received a Treatment Called Larotrectinib From a Study Called SCOUT With Patient Data From an External Database

Who this might be right for
Locally Advanced or Metastatic Infantile Fibrosarcoma Harboring an NTRK Gene FusionInfantile Fibrosarcoma
Bayer 93
Not applicableLooking for participantsNCT07755826
What this trial is testing

Repotrectinib Post-Marketing Surveillance in Pediatric Patients With NTRK Fusion-Positive Tumors in Japan

Who this might be right for
NTRK Fusion-positive Solid Tumors
Bristol-Myers Squibb 20
Not applicableApproved For MarketingNCT03025360
What this trial is testing

Expanded Access to Provide Larotrectinib for the Treatment of Cancers With a NTRK Gene Fusion

Who this might be right for
Tumors Harboring NTRK Fusion
Bayer
Testing effectiveness (Phase 2)Looking for participantsNCT05745623
What this trial is testing

Study of ICP-723 in Patients With Advanced Solid Tumors or Primary Central Nervous System Tumors

Who this might be right for
Advanced Solid Tumors Harboring NTRK FusionPrimary Central Nervous System Tumors Harboring NTRK Fusion
Beijing InnoCare Pharma Tech Co., Ltd. 70
Not applicableStudy completedNCT05793281
What this trial is testing

An Observational Study to Learn More About NTRK Gene Fusion Positive in Solid Tumor in Japan

Who this might be right for
Advanced or Recurrent Solid Tumor Harboring an NTRK Gene Fusion
Bayer 46,621
Not applicableStudy completedNCT06837090
What this trial is testing

Retrospective Analysis of the Experience With Larotrectinib in Patients With Solid Neoplasms With NTRK Fusion in Spain (SPAINTRK)

Who this might be right for
Solid Neoplasms With NTRK Fusions
Grupo Espanol de Tumores Neuroendocrinos 20
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