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Results for “NTRK Fusion Positive”

29 trials

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Showing 20 of 29 results

Early research (Phase 1)Study completedNCT03215511
What this trial is testing

Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat Cancer

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 81
Not applicableNo Longer AvailableNCT03206931
What this trial is testing

Expanded Access to Provide Selitrectinib for the Treatment of Cancers With a NTRK Gene Fusion

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer
Testing effectiveness (Phase 2)Active Not RecruitingNCT02637687
What this trial is testing

Test the Safety and Efficacy of the Drug Larotrectinib for the Treatment of Tumors With NTRK-fusion in Children

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 154
Early research (Phase 1)Ended earlyNCT03182257
What this trial is testing

Study of ONO-7579 in Patients With Advanced Solid Tumors/ NTRK Gene Fusion Positive Advanced Solid Tumors

Who this might be right for
Solid Tumor
Ono Pharmaceutical Co. Ltd 1
Testing effectiveness (Phase 2)Looking for participantsNCT06239272
What this trial is testing

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

Who this might be right for
Adipocytic NeoplasmLiposarcomaAtypical Fibroxanthoma+6 more
St. Jude Children's Research Hospital 139
Testing effectiveness (Phase 2)Looking for participantsNCT07394374
What this trial is testing

CG001419 Tablets in Adult Subjects With Locally Advanced or Metastatic Solid Tumours Harbouring NTRK Gene Abnormalities

Who this might be right for
Solid Tumors Harboring NTRK FusionNTRKNTRK Gene Fusion+1 more
Cullgen (Shanghai),Inc 42
Testing effectiveness (Phase 2)Active Not RecruitingNCT03834961
What this trial is testing

Larotrectinib in Treating Patients With Previously Untreated TRK Fusion Solid Tumors and TRK Fusion Relapsed Acute Leukemia

Who this might be right for
Central Nervous System NeoplasmInfantile FibrosarcomaRecurrent Acute Leukemia+2 more
Children's Oncology Group 33
Early research (Phase 1)Study completedNCT02122913
What this trial is testing

Test the Safety of the Investigational Drug Larotrectinib in Adults That May Treat Cancer

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 75
Not applicableUnknownNCT04921553
What this trial is testing

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING)

Who this might be right for
CancerCancer MetastaticNTRK Gene Fusion Overexpression+13 more
Centre Leon Berard 500
Early research (Phase 1)Study completedNCT02675491
What this trial is testing

Phase 1 Study of DS-6051b in Japanese Subjects With Advanced Solid Malignant Tumors

Who this might be right for
Advanced Solid Malignant Tumors
Daiichi Sankyo Co., Ltd. 15
Not applicableLooking for participantsNCT06837090
What this trial is testing

Retrospective Analysis of the Experience With Larotrectinib in Patients With Solid Neoplasms With NTRK Fusion in Spain (SPAINTRK)

Who this might be right for
Solid Neoplasms With NTRK Fusions
Grupo Espanol de Tumores Neuroendocrinos 19
Not applicableStudy completedNCT05793281
What this trial is testing

An Observational Study to Learn More About NTRK Gene Fusion Positive in Solid Tumor in Japan

Who this might be right for
Advanced or Recurrent Solid Tumor Harboring an NTRK Gene Fusion
Bayer 46,621
Early research (Phase 1)Study completedNCT04275960
What this trial is testing

Study in Healthy Adult Male Participants to Gather Information How the Human Body Absorbs, Distributes and Excretes the Study Drug Selitrectinib Including the Effect of the Interaction of Food With the Study Drug on the Human Body

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 24
Testing effectiveness (Phase 2)Active Not RecruitingNCT03944772
What this trial is testing

Phase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)

Who this might be right for
Non-Small Cell Lung Cancer
AstraZeneca 247
Testing effectiveness (Phase 2)Looking for participantsNCT05745623
What this trial is testing

Study of ICP-723 in Patients With Advanced Solid Tumors or Primary Central Nervous System Tumors

Who this might be right for
Advanced Solid Tumors Harboring NTRK FusionPrimary Central Nervous System Tumors Harboring NTRK Fusion
Beijing InnoCare Pharma Tech Co., Ltd. 70
Not applicableStudy completedNCT05236257
What this trial is testing

A Study Called EPI VITRAKVI to Compare Treatment Results in Patients With Infantile Fibrosarcoma (IFS), a Type of Connective Soft Tissue Cancer, Who Received a Treatment Called Larotrectinib From a Study Called SCOUT With Patient Data From an External Database

Who this might be right for
Locally Advanced or Metastatic Infantile Fibrosarcoma Harboring an NTRK Gene FusionInfantile Fibrosarcoma
Bayer 93
Early research (Phase 1)Study completedNCT04771390
What this trial is testing

Study to Compare How the Body Absorbs, Distributes and Excretes the Drug Selitrectinib (BAY2731954) Given as Two Different Tablet Formulations or as Liquid Formulations Including the Effect of Food on the Absorption, Distribution or Excretion of the Different Formulations in Healthy Participants

Who this might be right for
Solid Tumors Harboring NTRK Fusion
Bayer 52
Not applicableStudy completedNCT04557813
What this trial is testing

Registry for Molecular Testing, Treatment and Outcome of Patients With Solid Tumors Harboring a NTRK Gene Fusion

Who this might be right for
NTRK Family Gene Mutation
iOMEDICO AG 88
Very early researchLooking for participantsNCT04655404
What this trial is testing

A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine Glioma
Nationwide Children's Hospital 15
Early research (Phase 1)Ended earlyNCT01804530
What this trial is testing

Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors

Who this might be right for
Solid TumorTumors of Any Histology With Activating Trk (NTRK) Point or NTRK Fusion MutationsTenosynovial Giant Cell Tumor
Plexxikon 59
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