Early research (Phase 1)Study completedNCT07543276What this trial is testingPharmacokinetic (PK) Evaluation of Nalmefene FormulationsWho this might be right forOpioid Overdose Knoa Pharma LLC 13
Not applicableStudy completedNCT02492581What this trial is testingUse of Selincro and Impact on Usual PracticeWho this might be right forAlcohol Dependence University of Bordeaux 700
Post-approval studies (Phase 4)Study completedNCT00000437What this trial is testingTobacco Dependence in Alcoholism Treatment (Nicotine Patch/Naltrexone)Who this might be right forAlcoholismSmoking The Scripps Research Institute 60
Early research (Phase 1)Study completedNCT03129347What this trial is testingPharmacokinetic Evaluation of Nalmefene Administered Intranasally to Healthy VolunteersWho this might be right forOpioid-Related Disorders National Institute on Drug Abuse (NIDA) 14
Post-approval studies (Phase 4)Study completedNCT00000450What this trial is testingNaltrexone Maintenance Treatment of AlcoholismWho this might be right forAlcoholism The Scripps Research Institute 159
Early research (Phase 1)Study completedNCT01969617What this trial is testingEffects of Nalmefene After Single Dose on the Blood Oxygen Level Dependent (BOLD) fMRI Signal in the Ventral Striatum to Reward Responding in the Monetary Incentive Delay Task (MIDT), in Non-treatment Seeking Subjects With Alcohol Dependence Following Alcohol ChallengeWho this might be right forAlcohol Dependence H. Lundbeck A/S 22
Post-approval studies (Phase 4)Ended earlyNCT02195817What this trial is testingStudy of 18 mg Selincro® As-needed Use, in the Treatment of Patients With Alcohol Dependence in Primary CareWho this might be right forAlcohol Dependence H. Lundbeck A/S 378
Early research (Phase 1)Study completedNCT06719986What this trial is testingPharmacodynamic Evaluation of Intramuscular Nalmefene Autoinjector 1.5 mg Compared to Intranasal Narcan 4 mgWho this might be right forOpioid Overdose Purdue Pharma LP 24
Large-scale testing (Phase 3)WithdrawnNCT06408714What this trial is testingNalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid OverdoseWho this might be right forOpioid OverdoseOpiate Overdose University of New Mexico
Post-approval studies (Phase 4)Study completedNCT02197598What this trial is testingTreatment of Patients Suffering of Alcohol Dependence and Impaired Liver Function With Selincro® As-needed UseWho this might be right forAlcohol Dependence H. Lundbeck A/S 45
Not applicableStudy completedNCT03096730What this trial is testingEffect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative HyperalgesiaWho this might be right forPainAnesthesia Tianjin Medical University General Hospital 150
Early research (Phase 1)Study completedNCT04759768What this trial is testingPharmacokinetic Evaluation of Intranasal NalmefeneWho this might be right forPharmacokinetics Opiant Pharmaceuticals Inc 68
Large-scale testing (Phase 3)Study completedNCT02382276What this trial is testingA Long-term Extension Study for the Phase 3 Study of Nalmefene (339-14-001) in Patients With Alcohol DependenceWho this might be right forAlcohol Dependence Otsuka Pharmaceutical Co., Ltd. 405
Large-scale testing (Phase 3)Study completedNCT00811720What this trial is testingEfficacy of Nalmefene in Patients With Alcohol DependenceWho this might be right forAlcohol Dependence H. Lundbeck A/S 598
Testing effectiveness (Phase 2)UnknownNCT02934919What this trial is testingEvaluation of Nalmefene in Impulse Control Disorders in Parkinson's Disease: A Prospective Open Label StudyWho this might be right forImpulse Control DisordersParkinson Disease University Hospital, Clermont-Ferrand 30
Large-scale testing (Phase 3)Looking for participantsNCT05540288What this trial is testingNAlmefene Versus Placebo in Addition to Treatment as Usual on Craving in Behavioural AddictionsWho this might be right forBehavioural Addiction Nantes University Hospital 266
Large-scale testing (Phase 3)Study completedNCT00812461What this trial is testingEfficacy of Nalmefene in Patients With Alcohol DependenceWho this might be right forAlcohol Dependence H. Lundbeck A/S 678
Large-scale testing (Phase 3)Study completedNCT02364947What this trial is testingA Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate the Effect of Nalmefene on Alcohol Consumption Reduction in Patients With Alcohol Dependence (Phase 3 Trial)Who this might be right forAlcohol Dependence Otsuka Pharmaceutical Co., Ltd. 678
Early research (Phase 1)Study completedNCT05219669What this trial is testingPharmacokinetic Evaluation of Intranasal Nalmefene Using Three Dosing RegimensWho this might be right forOpioid Overdose Opiant Pharmaceuticals Inc 24
Post-approval studies (Phase 4)Study completedNCT04713358What this trial is testingEffect of Nalmefene on the Quality of Resuscitation in Patients Under General AnesthesiaWho this might be right forResuscitation RenJi Hospital 542