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Results for “Neoadjuvant Melanoma”

107 trials

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Showing 20 of 107 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03757689
What this trial is testing

Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma

Who this might be right for
Melanoma
Abramson Cancer Center at Penn Medicine 63
Testing effectiveness (Phase 2)Ended earlyNCT04310397
What this trial is testing

Dabrafenib, Trametinib, and Spartalizumab for the Treatment of BRAF V600E or V600K Mutation Positive Stage IIIB/C/D Melanoma

Who this might be right for
Pathologic Stage IIIB Cutaneous Melanoma AJCC v8Pathologic Stage IIIC Cutaneous Melanoma AJCC v8Pathologic Stage IIID Cutaneous Melanoma AJCC v8
M.D. Anderson Cancer Center 4
Testing effectiveness (Phase 2)Active Not RecruitingNCT04722575
What this trial is testing

Combination or Sequence of Vemurafenib, Cobimetinib, and Atezolizumab in High-risk, Resectable Melanoma

Who this might be right for
Melanoma
Fondazione Melanoma Onlus 95
Testing effectiveness (Phase 2)Ended earlyNCT04221438
What this trial is testing

Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement

Who this might be right for
Melanoma of Unknown PrimaryMetastatic Malignant Neoplasm in Lymph NodePathologic Stage IIIB Cutaneous Melanoma AJCC v8+3 more
ECOG-ACRIN Cancer Research Group 3
Not applicableLooking for participantsNCT07586891
What this trial is testing

Exploratory Study With Parallel Controls on the Safety and Efficacy of Neoadjuvant Low Branched-Chain Amino Acid Diet in Combination With Anti-PD-1 Monoclonal Antibody for Stage III Melanoma

Who this might be right for
Melanoma (Skin Cancer)
Xijing Hospital 80
Testing effectiveness (Phase 2)Study completedNCT03554083
What this trial is testing

Vemurafenib, Cobimetinib, Atezolizumab, and Tiragolumab in Treating Patients With High-Risk Stage III Melanoma

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Pathologic Stage III Cutaneous Melanoma AJCC v8Pathologic Stage IIIA Cutaneous Melanoma AJCC v8+3 more
Mayo Clinic 64
Very early researchLooking for participantsNCT07586904
What this trial is testing

Efficacy and Safety of Neoadjuvant Cadonilimab Plus High-Dose Recombinant Human Interferon α1b in Stage III/IV Melanoma.

Who this might be right for
Melanoma (Skin Cancer)
Xijing Hospital 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT05907954
What this trial is testing

(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma

Who this might be right for
Uveal Melanoma
IDEAYA Biosciences 160
Early research (Phase 1)Active Not RecruitingNCT05176470
What this trial is testing

Neoadj Admin Autologous Tumor Infiltrating Lymphocytes & Pembrolizumab for Treatment of Adv Melanoma Patients

Who this might be right for
Locally Advanced MelanomaPathologic Stage IIIB Cutaneous Melanoma AJCC v8Pathologic Stage IIIC Cutaneous Melanoma AJCC v8+2 more
Richard Wu 2
Testing effectiveness (Phase 2)UnknownNCT02968303
What this trial is testing

Induction Therapy With Vemurafenib and Cobimetinib to Optimize Nivolumab and Ipilimumab Therapy

Who this might be right for
Melanoma, Malignant, of Soft Parts
Radboud University Medical Center 200
Testing effectiveness (Phase 2)Looking for participantsNCT06999980
What this trial is testing

Neo IRENIE (NEOadjuvant Ipilimumab, RElatlimab, NIvolumab Evaluation)

Who this might be right for
Cutaneous MelanomaMucosal Melanoma
Melanoma Institute Australia 494
Testing effectiveness (Phase 2)Looking for participantsNCT07614828
What this trial is testing

Exploratory Clinical Study of Neoadjuvant Immunotherapy Combined With Chemotherapy in Malignant Melanoma of Nasal and Paranasal Mucosa

Who this might be right for
Mucosal Melanoma of the Head and Neck
Eye & ENT Hospital of Fudan University 25
Testing effectiveness (Phase 2)Ended earlyNCT04799054
What this trial is testing

TransCon TLR7/8 Agonist With or Without Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorLocally Advanced Solid TumorMetastatic Solid Tumor+4 more
Ascendis Pharma Oncology Division A/S 188
Large-scale testing (Phase 3)Looking for participantsNCT06794775
What this trial is testing

SWE-NEO: Swedish NeoAdjuvant Trial Comparing Monotherapy to Combined Immunotherapy in Resectable Stage III Melanoma

Who this might be right for
Malignant Melanoma Stage III
Hildur Helgadottir 128
Early research (Phase 1)Active Not RecruitingNCT04020809
What this trial is testing

Neoadjuvant Atezolizumab in Cutaneous Melanoma

Who this might be right for
Cutaneous Melanoma
The Methodist Hospital Research Institute 20
Testing effectiveness (Phase 2)Looking for participantsNCT06240143
What this trial is testing

Intradermal Ipilimumab and Nivolumab in High Risk Stage II Melanoma

Who this might be right for
Melanoma
The Netherlands Cancer Institute 96
Testing effectiveness (Phase 2)UnknownNCT02036086
What this trial is testing

Study of Neo-adjuvant Use of Vemurafenib Plus Cobimetinib for BRAF Mutant Melanoma With Palpable Lymph Node Metastases

Who this might be right for
Melanoma
Sunnybrook Health Sciences Centre 24
Large-scale testing (Phase 3)Looking for participantsNCT03567889
What this trial is testing

Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C/D Melanoma Patients

Who this might be right for
Melanoma Stage IIIBMelanoma Stage IIICMelanoma Stage IIID
Philogen S.p.A. 186
Not applicableLooking for participantsNCT06754904
What this trial is testing

Omitting Therapeutic Lymph Node Dissection in Patients With Melanoma (Stage 3) and Major Pathological Response in the Index Lymph Node

Who this might be right for
Melanoma, Skin
D.J. (Dirk) Grünhagen 213
Testing effectiveness (Phase 2)Looking for participantsNCT06548789
What this trial is testing

Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED

Who this might be right for
Melanoma
M.D. Anderson Cancer Center 35
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