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Results for “Neurofibromatosis 2”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Looking for participantsNCT06666348
What this trial is testing

Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK

Who this might be right for
Pediatric Low-grade Glioma
St. Justine's Hospital 50
Testing effectiveness (Phase 2)WithdrawnNCT03109301
What this trial is testing

Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

Who this might be right for
Neoplasms, Nerve TissueNeurofibromatosis 1Heredodegenerative Disorders, Nervous System+1 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT03672838
What this trial is testing

A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)

Who this might be right for
Neurofibromatosis 1 and 2 (NF1 and NF2)
NYU Langone Health 33
Testing effectiveness (Phase 2)Study completedNCT01207687
What this trial is testing

Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2)

Who this might be right for
Vestibular SchwannomaNeurofibromatosis Type 2
National Cancer Institute (NCI) 14
Large-scale testing (Phase 3)Ended earlyNCT03710564
What this trial is testing

Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF Injections

Who this might be right for
Age-Related Macular Degeneration
Novartis Pharmaceuticals 535
Very early researchStudy completedNCT00863122
What this trial is testing

Concentration and Activity of Lapatinib in Vestibular Schwannomas

Who this might be right for
Vestibular SchwannomaNF2Neurofibromatosis 2+2 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 26
Testing effectiveness (Phase 2)Ended earlyNCT02177825
What this trial is testing

Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas

Who this might be right for
Plexiform Neurofibromas
St. Justine's Hospital 5
Testing effectiveness (Phase 2)Looking for participantsNCT04374305
What this trial is testing

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

Who this might be right for
Neurofibromatosis Type 2Vestibular SchwannomaNon-vestibular Schwannoma+2 more
Scott R. Plotkin, MD, PhD 109
Not applicableUnknownNCT05821790
What this trial is testing

Role of the Tumor Microenvironment in Aggressive Meningiomas

Who this might be right for
Meningioma
Assistance Publique - Hôpitaux de Paris 40
Early research (Phase 1)Active Not RecruitingNCT06104488
What this trial is testing

Avutometinib for People With Solid Tumor Cancers

Who this might be right for
Refractory CancerCNS TumorsCNS Tumor, Adult+12 more
Memorial Sloan Kettering Cancer Center 3
Early research (Phase 1)Ended earlyNCT05228015
What this trial is testing

Oral TEAD Inhibitor Targeting the Hippo Pathway in Subjects with Advanced Solid Tumors

Who this might be right for
Solid Tumors, AdultSolid TumorMalignant Pleural Mesothelioma (MPM)+5 more
Ikena Oncology 67
Very early researchEnded earlyNCT02282917
What this trial is testing

Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma

Who this might be right for
Vestibular SchwannomaMeningiomaAcoustic Neuroma+1 more
Massachusetts Eye and Ear Infirmary 7
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07713745
What this trial is testing

Platform Research for Innovative Medicines in NF2-SWN (PRIME-NF2)

Who this might be right for
Neurofibromatosis Type 2Vestibular SchwannomaNon-vestibular Schwannoma+4 more
Beijing Tiantan Hospital 200
Not applicableEnded earlyNCT01736267
What this trial is testing

Auditory Brainstem Implant (ABI) in Adult Non-Neurofibromatosis Type 2 Subjects

Who this might be right for
Bilateral Hearing Loss for Causes Other Than Tumors
Massachusetts Eye and Ear Infirmary 3
Not applicableStudy completedNCT03210285
What this trial is testing

WES of NF2-associated in Comparison to Sporadic Vestibular Schwannomas - Correlation With Clinical Data

Who this might be right for
Neurofibromatosis Type 2Vestibular SchwannomaAcoustic Neuroma
University Hospital Tuebingen 70
Not applicableStudy completedNCT01222728
What this trial is testing

Using Positron Emission Tomography to Predict Intracranial Tumor Growth in Neurofibromatosis Type II Patients

Who this might be right for
NeoplasmsNervous System DiseaseVestibular Disease
National Institute of Neurological Disorders and Stroke (NINDS) 5
Post-approval studies (Phase 4)WithdrawnNCT00588172
What this trial is testing

Genetic Variation in OCT1 and Response to Metformin

Who this might be right for
Type 2 Diabetes
Mayo Clinic
Testing effectiveness (Phase 2)Study completedNCT01024946
What this trial is testing

Everolimus (RAD001) for the Treatment of Malignant Pleural Mesothelioma With Merlin/NF2 Loss as a Biomarker to Predict Sensitivity

Who this might be right for
Malignant Pleural Mesothelioma
Memorial Sloan Kettering Cancer Center 11
Early research (Phase 1)WithdrawnNCT01850225
What this trial is testing

Feasibility Study of Auditory Brainstem Implant in Young Children

Who this might be right for
Bilateral Cochlear AplasiaBilateral Cochlear Nerve DeficiencyBilateral Cochlear Ossification Secondary to Meningitis
House Research Institute
Not applicableEnded earlyNCT01864291
What this trial is testing

Auditory Brainstem Implant (ABI) in Pediatric Non-Neurofibromatosis Type 2 Subjects

Who this might be right for
Bilateral Hearing Loss for Causes Other Than Tumors
Massachusetts Eye and Ear Infirmary 9
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