Testing effectiveness (Phase 2)Active Not RecruitingNCT05521048What this trial is testingDoxycycline in Cutaneous Schwannoma (NF2)Who this might be right forNeurofibromatosis Type 2 Massachusetts Eye and Ear Infirmary 19
Not applicableStudy completedNCT02298270What this trial is testingResiliency Training for Patients With Neurofibromatosis Via Videoconferencing With SkypeWho this might be right forNeurofibromatosisNeurofibromatosis INeurofibromatosis 2+1 more Massachusetts General Hospital 65
Not applicableUnknownNCT04890132What this trial is testingVestibular Precision: Physiology & PathophysiologyWho this might be right forVestibular SchwannomaInner Ear DiseaseDizziness+2 more Massachusetts Eye and Ear Infirmary 90
Early research (Phase 1)Study completedNCT02102256What this trial is testingA Safety Study of the Auditory Brainstem Implant for Pediatric Profoundly Deaf PatientsWho this might be right forProfound Bilateral Deafness Due toBilateral Cochlear AplasiaBilateral Cochlear Nerve Deficiency+1 more Laurie Eisenberg 10
Testing effectiveness (Phase 2)Looking for participantsNCT05253131What this trial is testingTrial of Selumetinib and Bromodomain Inhibitor With Durvalumab for SarcomasWho this might be right forMPNSTNF1Sarcoma University of Alabama at Birmingham 41
Early research (Phase 1)Study completedNCT02955472What this trial is testingBioequivalence Study of Two Formulations of Pregabalin CR (Controlled-release) Table 150 mgWho this might be right forHealthy GL Pharm Tech Corporation 24
Not applicableStudy completedNCT02811718What this trial is testingResiliency Training for Patients With NF2 Via Videoconferencing With SkypeWho this might be right forNeurofibromatosis 2 Massachusetts General Hospital 45
Not applicableActive Not RecruitingNCT06175637What this trial is testingObservational Study to Evaluate the Effect and Safety of Selumetinib in Pediatric Patients With NF1-PNsWho this might be right forNeurofibroma, Plexiform AstraZeneca 409
Testing effectiveness (Phase 2)Study completedNCT03989115What this trial is testingDose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLCWho this might be right forSolid Tumor Revolution Medicines, Inc. 113
Testing effectiveness (Phase 2)Study completedNCT02352844What this trial is testingEverolimus in Patients With Advanced Solid Malignancies With TSC1, TSC2, NF1, NF2, or STK11 MutationsWho this might be right forSolid MalignancySolid Tumor Washington University School of Medicine 12
Testing effectiveness (Phase 2)Ended earlyNCT05554354What this trial is testingTesting the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial)Who this might be right forAnatomic Stage IV Breast Cancer AJCC v8Metastatic HER2-Negative Breast CarcinomaMetastatic Hormone Receptor-Positive Breast Carcinoma National Cancer Institute (NCI) 1
Testing effectiveness (Phase 2)Active Not RecruitingNCT02407405What this trial is testingMEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform NeurofibromasWho this might be right forNeurofibromatosis 1 (NF1)Plexiform Neurofibromas (PN) National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Looking for participantsNCT06541847What this trial is testingA Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1Who this might be right forNeurofibromatosis Type 1 Healx Limited 25
Not applicableLooking for participantsNCT03893643What this trial is testingCutaneous and Mucosal Manifestations of Neurofribromatosis Type 2 in Children Under 15Who this might be right forNeurofibromatosis 2Dermatology/Skin - Other Centre Hospitalier Universitaire de Nice 1,000
Testing effectiveness (Phase 2)Looking for participantsNCT06188741What this trial is testingSelumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1Who this might be right forNeurofibromatosis 1Plexiform Neurofibroma University of Alabama at Birmingham 200
Large-scale testing (Phase 3)Ended earlyNCT05130866What this trial is testingEfficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated MeningiomasWho this might be right forNeurofibromatosis Type 2 Recursion Pharmaceuticals Inc. 25
Not applicableActive Not RecruitingNCT04759781What this trial is testingMElanoma Research Lymph Node Prediction Implementation National_001Who this might be right forMelanoma SkylineDx 1,820
Testing effectiveness (Phase 2)Study completedNCT03433183What this trial is testingSARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath TumorsWho this might be right forMalignant Peripheral Nerve Sheath TumorsNeurofibromatosis 1 Sarcoma Alliance for Research through Collaboration 21
Testing effectiveness (Phase 2)Ended earlyNCT00911248What this trial is testingPTC299 for Treatment of Neurofibromatosis Type 2Who this might be right forNeurofibromatosis 2 PTC Therapeutics 11
Not applicableStudy completedNCT07420751What this trial is testingAssessment of Patient Experience With Auto-Captioning Glasses in NF2-Related-SchwannomatosisWho this might be right forNF2-related Schwannomatosis Massachusetts General Hospital 18