Not applicableUnknownNCT01218139What this trial is testingAnalysis of Peripheral Nerve Sheath Tumors (PNSTs) in Neurofibromatosis Type 1 (NF1) PatientsWho this might be right forNeurofibromatosis Type 1 KU Leuven 50
Not applicableUnknownNCT01218152What this trial is testingMicroarray CGH Analysis of Circulating Tumoral Plasma DNA in NF1 Patients With MPNSTsWho this might be right forNeurofibromatosis Type 1 KU Leuven 20
Testing effectiveness (Phase 2)Study completedNCT00589784What this trial is testingPhase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable MeningiomaWho this might be right forCNS CancerMeningiomaIntracranial Hemangiopericytoma+2 more Memorial Sloan Kettering Cancer Center 50
Not applicableWithdrawnNCT01567787What this trial is testingProton Radiation Therapy for Spinal TumorsWho this might be right forNerve Sheath TumorsNeurofibroma University of Florida
Testing effectiveness (Phase 2)Active Not RecruitingNCT03872427What this trial is testingTesting Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN StudyWho this might be right forAdvanced Malignant Solid NeoplasmMetastatic Malignant Solid NeoplasmNF1 Mutation Positive Malignant Peripheral Nerve Sheath Tumor+1 more National Cancer Institute (NCI) 54
Testing effectiveness (Phase 2)Ended earlyNCT05011019What this trial is testingA Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I NeurofibromatosisWho this might be right forNeurofibromatosis and Malignant Peripheral Nerve Sheath Tumors Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 22
Large-scale testing (Phase 3)Ended earlyNCT00427583What this trial is testingImatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath TumorsWho this might be right forMalignant Peripheral Nerve Sheath Tumors Novartis Pharmaceuticals 11
Early research (Phase 1)Study completedNCT02211768What this trial is testingTransformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1Who this might be right forNeurofibromatosisMPNST National Cancer Institute (NCI) 10
Early research (Phase 1)Study completedNCT02700230What this trial is testingVaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by SurgeryWho this might be right forMetastatic Malignant Peripheral Nerve Sheath TumorNeurofibromatosis Type 1Recurrent Malignant Peripheral Nerve Sheath Tumor Mayo Clinic 9
Testing effectiveness (Phase 2)Study completedNCT01661283What this trial is testingSARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath TumorsWho this might be right forMalignant Peripheral Nerve Sheath TumorsMPNSTSarcoma Sarcoma Alliance for Research through Collaboration 25
Not applicableActive Not RecruitingNCT05677594What this trial is testingMulti-parametric Biomarker Development to Predict Malignant Conversion in Patients With Neurofibromatosis Type 1Who this might be right forNeurofibromatosis 1Malignant Peripheral Nerve Sheath Tumor (MPNST) of Soft Tissue (Diagnosis)Atypical Neurofibroma Johns Hopkins University 80
Not applicableLooking for participantsNCT06222203What this trial is testingSurveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)Who this might be right forNeurofibromatosis 1Nerve Sheath Neoplasms National Cancer Institute (NCI) 225
Not applicableUnknownNCT01777451What this trial is testingWhole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in NeurofibromatosisWho this might be right forWhole Body ImagingMagnetic Resonance ImagingNeurofibromatosis 1+2 more Universitaire Ziekenhuizen KU Leuven 30
Not applicableActive Not RecruitingNCT00924196What this trial is testingNatural History Study of Patients With Neurofibromatosis Type IWho this might be right forNeurofibromatosis Type 1Malignant Peripheral Nerve Sheath TumorPlexiform Neurofibroma+2 more National Cancer Institute (NCI) 259
Testing effectiveness (Phase 2)WithdrawnNCT02986919What this trial is testingStudy of CPI-0610 in Patients With Malignant Peripheral Nerve Sheath TumorsWho this might be right forPeripheral Nerve Tumors University of Texas Southwestern Medical Center
Not applicableEnrolling By InvitationNCT06515860What this trial is testingNeurofibromatosis Type 1 Tumor Early Detection StudyWho this might be right forNeurofibromatosis Type 1Neurofibromatosis 1Plexiform Neurofibroma+4 more David Miller 1,000
Testing effectiveness (Phase 2)Looking for participantsNCT05253131What this trial is testingTrial of Selumetinib and Bromodomain Inhibitor With Durvalumab for SarcomasWho this might be right forMPNSTNF1Sarcoma University of Alabama at Birmingham 41
Not applicableLooking for participantsNCT07298083What this trial is testingDoD Award NF230020 Identification of Metabolic Markers and Statistical Prediction of MPNST for Rapid Diagnosis and Assessment of Surgical MarginsWho this might be right forNeurofibromasMPNST M.D. Anderson Cancer Center 60
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07743554What this trial is testingCombination of Avutometinib and Defactinib for Treatment of Relapsed, Refractory, Metastatic, or Unresectable Malignant Peripheral Nerve Sheath TumorWho this might be right forMPNST (Malignant Peripheral Nerve Sheath Tumor) Girish Dhall, MD 23
Testing effectiveness (Phase 2)Study completedNCT03433183What this trial is testingSARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath TumorsWho this might be right forMalignant Peripheral Nerve Sheath TumorsNeurofibromatosis 1 Sarcoma Alliance for Research through Collaboration 21