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Results for “Neurofibromatosis-1”

175 trials

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Showing 20 of 175 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT05253131
What this trial is testing

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

Who this might be right for
MPNSTNF1Sarcoma
University of Alabama at Birmingham 41
Very early researchStudy completedNCT00657202
What this trial is testing

Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1

Who this might be right for
Neurofibromatosis Type 1Cutaneous Neurofibromas
Massachusetts General Hospital 11
Not applicableUnknownNCT03757247
What this trial is testing

Prevalence of Constitutional Mismatch-repair Deficiency Among Suspected Neurofibromatosis Type 1/Legius Syndrome Children Without a Malignancy and Without a NF1 or SPRED1 Mutation

Who this might be right for
Neurofibromatosis Type 1
Medical University Innsbruck 670
Not applicableEnrolling By InvitationNCT05238909
What this trial is testing

Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1

Who this might be right for
Neurofibromatosis 1NF1Neurofibromatosis Type 1
Ann & Robert H Lurie Children's Hospital of Chicago 200
Not applicableStudy completedNCT03531814
What this trial is testing

Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1(NF1) on Clinical Treatment Trials

Who this might be right for
Neurofibromatosis 1Neurofibroma, Plexiform
National Cancer Institute (NCI) 12
Not applicableStudy completedNCT02422732
What this trial is testing

Functional Imaging and Reading Deficit in Children With NF1

Who this might be right for
Neurofibromatosis Type 1
University Hospital, Toulouse 25
Not applicableStudy completedNCT05377008
What this trial is testing

Intervention Effectiveness on the Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1

Who this might be right for
Neurocognitive DeficitMental Health ImpairmentNeurofibromatosis 1
Virginia Commonwealth University 38
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06735820
What this trial is testing

Early Phase Study Evaluating MEK and MDM2 Inhibition in Patients With NF1 and MPNST

Who this might be right for
Malignant Peripheral Nerve Sheath Tumor (MPNST)Neurofibromatosis 1 (NF1)Atypical Neurofibroma
AeRang Kim 45
Early research (Phase 1)Ended earlyNCT04800822
What this trial is testing

PF-07284892 in Participants With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Pfizer 53
Testing effectiveness (Phase 2)Looking for participantsNCT06159166
What this trial is testing

Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).

Who this might be right for
NF1Cutaneous NeurofibromaMonotherapy
Johns Hopkins University 24
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06620354
What this trial is testing

Clinical Study on the Treatment of Type I Neurofibromatosis With Smeitinib Hydrosulfate Capsule

Who this might be right for
Neurofibromatosis 1
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 33
Not applicableStudy completedNCT03826940
What this trial is testing

From Molecules to Cognition: Inhibitory Mechanisms in ASD and NF1

Who this might be right for
Autism Spectrum DisorderNeurofibromatosis 1
University of Coimbra 16
Not applicableStudy completedNCT01058330
What this trial is testing

Effects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1

Who this might be right for
Neurofibromatosis Type 1
Shriners Hospitals for Children 36
Not applicableLooking for participantsNCT06379230
What this trial is testing

A Retrospective Study on Epidemiological Characteristics of Chinese NF1 Patients in Real World (PROMISE)

Who this might be right for
Neurofibromatosis 1Plexiform Neurofibroma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 2,000
Not applicableLooking for participantsNCT06262113
What this trial is testing

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

Who this might be right for
Neurofibromatosis 1
Massachusetts General Hospital 294
Testing effectiveness (Phase 2)Active Not RecruitingNCT01089101
What this trial is testing

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

Who this might be right for
Low Grade GliomaRecurrent Childhood Pilocytic AstrocytomaRecurrent Neurofibromatosis Type 1+3 more
National Cancer Institute (NCI) 217
Early research (Phase 1)Active Not RecruitingNCT04590235
What this trial is testing

Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)

Who this might be right for
Neurofibromatosis 1Neurofibroma Plexiform
AstraZeneca 32
Not applicableUnknownNCT03981510
What this trial is testing

Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation

Who this might be right for
ConstipationChildhood Acute Lymphoblastic LeukemiaNeurofibromatosis 1+1 more
University of Aarhus 80
Not applicableUnknownNCT04856514
What this trial is testing

Open Trial of Telehealth Group for Improving Peer Relationships (PEERS) in NF1

Who this might be right for
Neurofibromatosis 1Social Skills
University of Wisconsin, Milwaukee 8
Early research (Phase 1)Enrolling By InvitationNCT06300502
What this trial is testing

Assessing the Efficacy of Repeat, Monthly Treatments of Deoxycholate for NF1 Associated Cutaneous Neurofibromas (cNFs)

Who this might be right for
Neurofibromas, CutaneousNeurofibromatosis 1
Massachusetts General Hospital 15
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