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Results for “Neuromuscular Junction Diseases”

389 trials

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Showing 20 of 389 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05644561
What this trial is testing

Evaluation of PK, PD, Efficacy, Safety, and Immunogenicity of IV Ravulizumab in Pediatric Participants With Generalized Myasthenia Gravis

Who this might be right for
Generalized Myasthenia GravisgMG
Alexion Pharmaceuticals, Inc. 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT06106672
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacodynamics and Efficacy of CNP-106 in Subjects With Myasthenia Gravis

Who this might be right for
Myasthenia GravisGeneralized MyastheniaAChR Myasthenia Gravis+1 more
COUR Pharmaceutical Development Company, Inc. 54
Not applicableStudy completedNCT04980807
What this trial is testing

Observational Study of Neuromuscular Function in CMT Type 1&2 and Healthy Controls

Who this might be right for
Charcot-Marie-Tooth Disease
NMD Pharma A/S 30
Testing effectiveness (Phase 2)UnknownNCT06580236
What this trial is testing

Study of the Drug B11-FC (Botulism Treatment)

Who this might be right for
Botulism
Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation 40
Not applicableEnrolling By InvitationNCT06605612
What this trial is testing

Development and Validation of the FBIndex to Determine the Risk of Falls for Patients With Neuromuscular Disorders

Who this might be right for
Inclusion Body MyositisMyotonic DystrophyLimb-girdle and Facioscapulohumeral Muscular Dystrophies+9 more
LMU Klinikum 108
Early research (Phase 1)Active Not RecruitingNCT06958939
What this trial is testing

The Safety and Efficacy of S103 in the Treatment of Refractory Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis, Generalized
Ting Chang, MD 10
Early research (Phase 1)Not Yet RecruitingNCT07676266
What this trial is testing

C-CAR168 in the Treatment of Autoimmune Diseases Refractory to Standard Therapy

Who this might be right for
Multiple Sclerosis (MS)Myasthenia Gravis (MG)Neuromyelitis Optica Spectrum Disorder+3 more
The Affiliated Hospital of Qingdao University 18
Testing effectiveness (Phase 2)Looking for participantsNCT06414954
What this trial is testing

Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients With Myasthenia Gravis

Who this might be right for
Myasthenia GravisMyasthenia Gravis, MuSK
NMD Pharma A/S 84
Early research (Phase 1)Looking for participantsNCT07085676
What this trial is testing

Phase 1 Study of HBI0101 CAR-T in Refractory B-Cell Autoimmune Diseases

Who this might be right for
Systemic Sclerosis (SSc)Idiopathic Inflammatory Myopathy (IIM)Rheumatoid Arthritis (RA)+6 more
Polina Stepensky 120
Not applicableLooking for participantsNCT06713993
What this trial is testing

Semmelweis Esophageal Cancer Study: Noninvasive Prognostic Parameters in Patients With Oesophageal and Esophagogastric Junction Cancer

Who this might be right for
Esophageal Cancer (EsC)
Semmelweis University 100
Large-scale testing (Phase 3)Looking for participantsNCT06765161
What this trial is testing

Efgartigimod in IVIG Dependent Myasthenia Gravis Patients

Who this might be right for
Myasthaenia Gravis
Clinique Neuro-Outaouais 30
Testing effectiveness (Phase 2)Study completedNCT03052751
What this trial is testing

Study to Test the Safety, Tolerability and Efficacy of UCB7665 in Subjects With Moderate to Severe Myasthenia Gravis

Who this might be right for
Myasthenia Gravis
UCB Biopharma S.P.R.L. 43
Not applicableNot Yet RecruitingNCT07337395
What this trial is testing

Proteomic Changes in Patients With Myasthenia Gravis and Ravulizumab

Who this might be right for
Myasthenia Gravis Generalised
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 24
Large-scale testing (Phase 3)Study completedNCT03759366
What this trial is testing

Open-Label Study of Eculizumab in Pediatric Participants With Refractory Generalized Myasthenia Gravis (gMG)

Who this might be right for
Myasthenia GravisMyasthenia Gravis, Juvenile FormMyasthenia Gravis, Generalized
Alexion Pharmaceuticals, Inc. 12
Not applicableTemporarily pausedNCT04031469
What this trial is testing

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease

Who this might be right for
Gut MicrobiomeGastrointestinal MicrobiomeAutism+77 more
ProgenaBiome 1,000
Not applicableStudy completedNCT03826056
What this trial is testing

Neurology Inpatient Clinical Education Trial

Who this might be right for
Myasthenia GravisGuillain-Barre SyndromeMultiple Sclerosis+8 more
Dartmouth-Hitchcock Medical Center 50
Post-approval studies (Phase 4)Enrolling By InvitationNCT02051062
What this trial is testing

BT-011 Pharmacokinetics of Botulism Antitoxin Heptavalent in Pediatric Patients

Who this might be right for
Botulism
Emergent BioSolutions 10
Testing effectiveness (Phase 2)Ended earlyNCT01268280
What this trial is testing

Pharmacodynamic Study of CK-2017357 in Patients With Generalized Myasthenia Gravis

Who this might be right for
Myasthenia Gravis
Cytokinetics 32
Not applicableActive Not RecruitingNCT07796776
What this trial is testing

The Aim of the Study is to Characterize Patients Exhibiting Muscular Atrophy and Weakness Who Require a Muscle Biopsy for Diagnosis (IBM vs Atypical MND), Through an Innovative Technique Which Enables the Evaluation of the Neuromuscular Junction Involvement in Each Condition

Who this might be right for
Inclusion Body Myositis (IBM)Motor Neuron Disease, Amyotrophic Lateral Sclerosis
IRCCS San Raffaele 30
Not applicableEnrolling By InvitationNCT00704626
What this trial is testing

Serum Auto-Antibodies in Neurological Diseases

Who this might be right for
Multiple SclerosisMyasthenia GravisTransverse Myelitis
University of California, Davis 120
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