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Results for “Newly Diagnosed Acute Myeloid Leukemia With High Risk”

59 trials

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Showing 20 of 59 results

Testing effectiveness (Phase 2)Study completedNCT03030612
What this trial is testing

ARGX-110 in Combination With Azacytidine in Participants With Newly Diagnosed Acute Myeloid Leukemia (AML) or High Risk Myelodysplatic Syndrome (MDS)

Who this might be right for
Leukemia, Myeloid, AcuteMyelodysplastic Syndromes
OncoVerity, Inc. 38
Testing effectiveness (Phase 2)Ended earlyNCT03404193
What this trial is testing

Venetoclax and Decitabine in Treating Participants With Relapsed/Refractory Acute Myeloid Leukemia or Relapsed High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeBlastic Plasmacytoid Dendritic Cell Neoplasm+12 more
M.D. Anderson Cancer Center 235
Testing effectiveness (Phase 2)Study completedNCT00096122
What this trial is testing

Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia (M7)+20 more
National Cancer Institute (NCI) 95
Testing effectiveness (Phase 2)Looking for participantsNCT06394011
What this trial is testing

Study of VA Combined With HAAG Regimen in Newly Diagnosed Intermediate and High-risk AML Patients

Who this might be right for
Intermediate Risk Acute Myeloid LeukemiaHigh Risk Acute Myeloid Leukemia
The First Affiliated Hospital of Soochow University 60
Testing effectiveness (Phase 2)Looking for participantsNCT04588922
What this trial is testing

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

Who this might be right for
Hematologic Malignancies
Sellas Life Sciences Group 160
Testing effectiveness (Phase 2)Study completedNCT01101880
What this trial is testing

Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative Neoplasm

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+8 more
University of Washington 50
Early research (Phase 1)Study completedNCT00093600
What this trial is testing

PKC412, Daunorubicin, and Cytarabine in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia (AML)
Novartis Pharmaceuticals 69
Testing effectiveness (Phase 2)Study completedNCT00002800
What this trial is testing

Chemotherapy in Treating Patients With Newly Diagnosed Acute or Chronic Myelogenous Leukemia or Myelodysplastic Syndrome

Who this might be right for
LeukemiaMyelodysplastic SyndromesNeutropenia
Memorial Sloan Kettering Cancer Center 60
Testing effectiveness (Phase 2)Study completedNCT02921061
What this trial is testing

Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS

Who this might be right for
Mixed Phenotype Acute LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Myeloid Leukemia+4 more
Fred Hutchinson Cancer Center 28
Testing effectiveness (Phase 2)Looking for participantsNCT06483906
What this trial is testing

Venetoclax and Azacitidine Combined With Homoharringtonine, Followed by Allo-HSCT for Intermediate and High-risk AML.

Who this might be right for
Acute Myeloid Leukemia
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 56
Testing effectiveness (Phase 2)Active Not RecruitingNCT03330821
What this trial is testing

Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAcute Myeloid Leukemia With Myelodysplasia-Related ChangesTherapy-Related Acute Myeloid Leukemia
University of Southern California 53
Large-scale testing (Phase 3)Study completedNCT00482833
What this trial is testing

Phase III Trial in Acute Promyelocytic Leukemia Patients

Who this might be right for
Leukemia
Gruppo Italiano Malattie EMatologiche dell'Adulto 276
Large-scale testing (Phase 3)UnknownNCT05175508
What this trial is testing

Aza With or Without ATRA in Newly Diagnosed Unfit AML or Intermediate,High or Very High Risk MDS

Who this might be right for
AMLMDSOld Age; Debility+1 more
The First Affiliated Hospital of Soochow University 180
Testing effectiveness (Phase 2)Study completedNCT01238211
What this trial is testing

Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeAdult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11+5 more
National Cancer Institute (NCI) 61
Testing effectiveness (Phase 2)Looking for participantsNCT04047641
What this trial is testing

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts 20 Percent or More of Bone Marrow Nucleated CellsHigh Risk Myelodysplastic Syndrome+5 more
M.D. Anderson Cancer Center 80
Early research (Phase 1)Active Not RecruitingNCT06034470
What this trial is testing

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMixed Phenotype Acute LeukemiaMyelodysplastic Syndrome+2 more
Fred Hutchinson Cancer Center 30
Testing effectiveness (Phase 2)Study completedNCT04230239
What this trial is testing

Clinical Trial to Assess the Efficacy and Toxicity of Induction and Consolidation With CPX-351 for Patients Aged 60 to 75 Years With Secondary or High-risk Acute Myeloid Leukemia

Who this might be right for
Newly Diagnosed Secondary or High Risk AML
PETHEMA Foundation 59
Early research (Phase 1)Ended earlyNCT00124644
What this trial is testing

Combination Chemotherapy and Tipifarnib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Leukemia
Ohio State University Comprehensive Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT05554406
What this trial is testing

Testing the Effects of Novel Therapeutics for Newly Diagnosed, Untreated Patients With High-Risk Acute Myeloid Leukemia (A MyeloMATCH Treatment Trial)

Who this might be right for
Acute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative NeoplasmAcute Myeloid Leukemia Post Cytotoxic Therapy+1 more
National Cancer Institute (NCI)
Large-scale testing (Phase 3)UnknownNCT00651261
What this trial is testing

Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Leukemia
Alliance for Clinical Trials in Oncology 717
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