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Results for “Newly Diagnosed Acute Myeloid Leukemia With High Risk”

59 trials

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Showing 20 of 59 results

Testing effectiveness (Phase 2)Looking for participantsNCT04588922
What this trial is testing

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

Who this might be right for
Hematologic Malignancies
Sellas Life Sciences Group 160
Testing effectiveness (Phase 2)Study completedNCT00096122
What this trial is testing

Idarubicin, Cytarabine, and Tipifarnib in Treating Patients With Newly Diagnosed Myelodysplastic Syndromes or Acute Myeloid Leukemia

Who this might be right for
Adult Acute Basophilic LeukemiaAdult Acute Eosinophilic LeukemiaAdult Acute Megakaryoblastic Leukemia (M7)+20 more
National Cancer Institute (NCI) 95
Testing effectiveness (Phase 2)Looking for participantsNCT06928376
What this trial is testing

RCT of "3+7" vs Venetoclax + CACAG in Newly Diagnosed Mid/High-Risk AML Patients

Who this might be right for
Acute Myeloid LeukemiaFirst Line Therapy
Chinese PLA General Hospital 160
Large-scale testing (Phase 3)Study completedNCT03092674
What this trial is testing

Azacitidine With or Without Nivolumab or Midostaurin, or Decitabine and Cytarabine Alone in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeMyelodysplastic Syndrome/Acute Myeloid Leukemia
National Cancer Institute (NCI) 76
Testing effectiveness (Phase 2)Looking for participantsNCT07046078
What this trial is testing

Combination Chemotherapy (FLAG-Ida) Followed Immediately by Reduced-Intensity Total Body Radiation Therapy and Donor Hematopoietic Cell Transplant for the Treatment of Adults Age 60 and Older With Newly Diagnosed Adverse-Risk Acute Myeloid Leukemia or Other High-Grade Myeloid Cancer

Who this might be right for
Acute Leukemia of Ambiguous LineageAcute Myeloid LeukemiaChronic Myelomonocytic Leukemia+1 more
Fred Hutchinson Cancer Center
Large-scale testing (Phase 3)UnknownNCT00651261
What this trial is testing

Daunorubicin, Cytarabine, and Midostaurin in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Leukemia
Alliance for Clinical Trials in Oncology 717
Early research (Phase 1)Active Not RecruitingNCT06034470
What this trial is testing

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMixed Phenotype Acute LeukemiaMyelodysplastic Syndrome+2 more
Fred Hutchinson Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT04047641
What this trial is testing

Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaBlasts 20 Percent or More of Bone Marrow Nucleated CellsHigh Risk Myelodysplastic Syndrome+5 more
M.D. Anderson Cancer Center 80
Large-scale testing (Phase 3)Ended earlyNCT01132547
What this trial is testing

Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer

Who this might be right for
Cancer
University of South Florida 22
Testing effectiveness (Phase 2)Ended earlyNCT02198482
What this trial is testing

Trial of Intensive Chemotherapy With or Without Volasertib in Patients With Newly Diagnosed High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia (AML)High-risk Myelodysplastic Syndrome (MDS)
University of Ulm 6
Testing effectiveness (Phase 2)Ended earlyNCT00666497
What this trial is testing

Phase 2 Study of Azacitidine (Vidaza) vs MGCD0103 vs Combination in Elderly Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)
Mirati Therapeutics Inc. 6
Testing effectiveness (Phase 2)Study completedNCT02921061
What this trial is testing

Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS

Who this might be right for
Mixed Phenotype Acute LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Myeloid Leukemia+4 more
Fred Hutchinson Cancer Center 28
Testing effectiveness (Phase 2)Study completedNCT01101880
What this trial is testing

Clofarabine, Cytarabine, and Filgrastim in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia, Advanced Myelodysplastic Syndrome, and/or Advanced Myeloproliferative Neoplasm

Who this might be right for
Adult Acute Myeloid Leukemia With 11q23 (MLL) AbnormalitiesAdult Acute Myeloid Leukemia With Del(5q)Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)+8 more
University of Washington 50
Large-scale testing (Phase 3)Study completedNCT00046930
What this trial is testing

Daunorubicin & Cytarabine +/- Zosuquidar inTreating Older Patients With Newly Diagnosed Acute Myeloid Leukemia or Refractory Anemia

Who this might be right for
LeukemiaMyelodysplastic Syndromes
Eastern Cooperative Oncology Group 449
Testing effectiveness (Phase 2)Study completedNCT00066248
What this trial is testing

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Who this might be right for
Brain TumorCentral Nervous System TumorsCachexia+5 more
University of South Florida 70
Early research (Phase 1)Looking for participantsNCT07177079
What this trial is testing

High-dose Ascorbate (HDA) in Combination With Standard of Care Azacitidine and Venetoclax in Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Kittika Poonsombudlert 30
Testing effectiveness (Phase 2)Study completedNCT00065143
What this trial is testing

Clofarabine Plus Cytarabine in Patients With Previously Untreated Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome

Who this might be right for
Leukemia, MyeloidMyelodysplastic Syndromes
M.D. Anderson Cancer Center 60
Testing effectiveness (Phase 2)Looking for participantsNCT00801489
What this trial is testing

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1+7 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT01358734
What this trial is testing

A Study Being Conducted at Multiple Locations to Compare Safety and Efficacy of Three Different Regimens; (1) High-Dose Lenalidomide; (2) Lenalidomide + Azacitidine; or (3) Azacitidine in Subjects ≥ 65 Years With Newly-Diagnosed Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaAcute Myelogenous Leukemia
Celgene 88
Early research (Phase 1)Ended earlyNCT00124644
What this trial is testing

Combination Chemotherapy and Tipifarnib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Leukemia
Ohio State University Comprehensive Cancer Center 30
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