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Results for “Newly Diagnosed Acute Myeloid Leukemia With High Risk”

58 trials

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Showing 20 of 58 results

Early research (Phase 1)Ended earlyNCT05155709
What this trial is testing

Siremadlin in Combination With Venetoclax Plus Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Chemotherapy.

Who this might be right for
Acute Myeloid Leukemia
Novartis Pharmaceuticals 14
Large-scale testing (Phase 3)Study completedNCT00880243
What this trial is testing

Effect of Priming During Induction and Consolidations in Younger Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia
Acute Leukemia French Association 473
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07153497
What this trial is testing

Testing the Use of an IDH1 Inhibitor, Olutasidenib, in Acute Myeloid Leukemia Added to ASTX727 and Venetoclax; in High-Risk MDS Added to ASTX727; and Alone in Low Risk MDS (A MyeloMATCH Treatment Substudy)

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Syndrome
National Cancer Institute (NCI) 132
Not applicableStudy completedNCT02121418
What this trial is testing

Decitabine and Cytarabine in Treating Older Patients With Newly Diagnosed Acute Myeloid Leukemia, High Risk Myelodysplastic Syndrome, or Myeloproliferative Neoplasm

Who this might be right for
Chronic Myelomonocytic Leukemia-2Myelodysplastic SyndromeMyeloproliferative Neoplasm+1 more
University of Washington 12
Testing effectiveness (Phase 2)Study completedNCT02728050
What this trial is testing

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone With Sorafenib in Treating Patients With Newly-Diagnosed, Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Biphenotypic LeukemiaAcute Myeloid Leukemiade Novo Myelodysplastic Syndrome+2 more
University of Washington 84
Large-scale testing (Phase 3)Not Yet RecruitingNCT07296445
What this trial is testing

A Trial to Investigate Whether Oral Arsenic Trioxide Is Similar to Intravenous Arsenic Trioxide in Pharmacokinetics, Safety, and Efficacy (LATITUDE/SDKARS-301)

Who this might be right for
Acute Promyelocytic Leukemia (APL)Acute Promyelocytic LeukaemiaAcute Promyelocytic Leukemia With PML-RARA+6 more
SDK Therapeutics, Inc. 120
Testing effectiveness (Phase 2)Study completedNCT02921061
What this trial is testing

Decitabine With GCLAM for Adults With Newly Diagnosed, Relapsed, or Refractory AML or High-Risk MDS

Who this might be right for
Mixed Phenotype Acute LeukemiaPreviously Treated Myelodysplastic SyndromeRecurrent Adult Acute Myeloid Leukemia+4 more
Fred Hutchinson Cancer Center 28
Testing effectiveness (Phase 2)Study completedNCT02044796
What this trial is testing

Filgrastim, Cladribine, Cytarabine, and Mitoxantrone Hydrochloride in Treating Patients With Newly Diagnosed or Relapsed/Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Who this might be right for
Acute Biphenotypic Leukemiade Novo Myelodysplastic SyndromePreviously Treated Myelodysplastic Syndrome+3 more
Fred Hutchinson Cancer Center 199
Testing effectiveness (Phase 2)Study completedNCT00932412
What this trial is testing

The CLARA Study From the Acute Leukemia French Association (ALFA 0702 Trial)

Who this might be right for
Acute Myeloid Leukemia
Hospices Civils de Lyon 735
Testing effectiveness (Phase 2)WithdrawnNCT05829434
What this trial is testing

Magrolimab Plus Intensive Chemotherapy in Newly Diagnosed AML or HR-MDS

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic Neoplasm
Uwe Platzbecker
Testing effectiveness (Phase 2)Ended earlyNCT00666497
What this trial is testing

Phase 2 Study of Azacitidine (Vidaza) vs MGCD0103 vs Combination in Elderly Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)
Mirati Therapeutics Inc. 6
Testing effectiveness (Phase 2)Ended earlyNCT02198482
What this trial is testing

Trial of Intensive Chemotherapy With or Without Volasertib in Patients With Newly Diagnosed High-Risk Myelodysplastic Syndrome (MDS) and Acute Myeloid Leukemia (AML)

Who this might be right for
Acute Myeloid Leukemia (AML)High-risk Myelodysplastic Syndrome (MDS)
University of Ulm 6
Early research (Phase 1)Study completedNCT02029950
What this trial is testing

Pomalidomide After Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaChronic Myelomonocytic Leukemia-2High Risk Myelodysplastic Syndrome+1 more
National Cancer Institute (NCI) 50
Early research (Phase 1)Looking for participantsNCT06034470
What this trial is testing

Combination Chemotherapy (FLAG-Ida) With Pivekimab Sunirine (PVEK [IMGN632]) for the Treatment of Newly Diagnosed Adverse Risk Acute Myeloid Leukemia and Other High-Grade Myeloid Neoplasms

Who this might be right for
Acute Myeloid LeukemiaMixed Phenotype Acute LeukemiaMyelodysplastic Syndrome+2 more
Fred Hutchinson Cancer Center 30
Post-approval studies (Phase 4)Study completedNCT00408278
What this trial is testing

Treatment of Newly Diagnosed Patients With Acute Promyelocytic Leukemia (PETHEMA LPA 2005)

Who this might be right for
Acute Promyelocytic Leukemia
PETHEMA Foundation 300
Early research (Phase 1)Ended earlyNCT00124644
What this trial is testing

Combination Chemotherapy and Tipifarnib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Who this might be right for
Leukemia
Ohio State University Comprehensive Cancer Center 30
Testing effectiveness (Phase 2)Looking for participantsNCT06483906
What this trial is testing

Venetoclax and Azacitidine Combined With Homoharringtonine, Followed by Allo-HSCT for Intermediate and High-risk AML.

Who this might be right for
Acute Myeloid Leukemia
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine 56
Testing effectiveness (Phase 2)Looking for participantsNCT05010122
What this trial is testing

ASTX727, Venetoclax, and Gilteritinib for the Treatment of Newly Diagnosed, Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromeRecurrent Acute Myeloid Leukemia+1 more
M.D. Anderson Cancer Center 42
Testing effectiveness (Phase 2)Looking for participantsNCT00801489
What this trial is testing

Fludarabine Phosphate, Cytarabine, Filgrastim-sndz, Gemtuzumab Ozogamicin, and Idarubicin Hydrochloride in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome

Who this might be right for
Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11Acute Myeloid Leukemia With t(16;16)(p13.1;q22); CBFB-MYH11Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1+7 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Study completedNCT00066248
What this trial is testing

Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Treatment

Who this might be right for
Brain TumorCentral Nervous System TumorsCachexia+5 more
University of South Florida 70
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