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Results for “Newly Diagnosed MGMT Unmethylated Glioblastoma”

36 trials

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Showing 20 of 36 results

Early research (Phase 1)Study completedNCT03452930
What this trial is testing

Tinostamustine With or Without Radiation Therapy in Treating Patients With Newly Diagnosed MGMT-Unmethylated Glioblastoma

Who this might be right for
GlioblastomaGliosarcomaMGMT-Unmethylated Glioblastoma
M.D. Anderson Cancer Center 5
Early research (Phase 1)Study completedNCT03726515
What this trial is testing

CART-EGFRvIII + Pembrolizumab in GBM

Who this might be right for
Glioblastoma
University of Pennsylvania 7
Large-scale testing (Phase 3)Looking for participantsNCT07452458
What this trial is testing

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

Who this might be right for
Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma
NRG Oncology 398
Testing effectiveness (Phase 2)Looking for participantsNCT06504381
What this trial is testing

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

Who this might be right for
High Grade GliomaMGMT-Unmethylated GlioblastomaMGMT-Methylated Glioblastoma
University of California, San Francisco 70
Early research (Phase 1)Ended earlyNCT03107780
What this trial is testing

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

Who this might be right for
GlioblastomaGliosarcomaMGMT-Unmethylated Glioblastoma+1 more
National Cancer Institute (NCI) 32
Early research (Phase 1)Looking for participantsNCT07343986
What this trial is testing

Study of Low-Intensity Focused Ultrasound in Combination With Immunotherapy in Newly Diagnosed Unmethylated Glioblastoma

Who this might be right for
Glioblastoma (GBM)
University of Virginia 12
Testing effectiveness (Phase 2)Study completedNCT03522298
What this trial is testing

Safety, Pharmacokinetics and Efficacy of Paxalisib (GDC-0084) in Newly-diagnosed Glioblastoma

Who this might be right for
Glioblastoma, Adult
Kazia Therapeutics Limited 30
Testing effectiveness (Phase 2)UnknownNCT04224441
What this trial is testing

Repurposing Chlorpromazine in the Treatment of Glioblastoma

Who this might be right for
Glioblastoma MultiformeMGMT-Unmethylated Glioblastoma
Marco G Paggi, MD, PhD 41
Testing effectiveness (Phase 2)Study completedNCT03050736
What this trial is testing

Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression

Who this might be right for
GliomaGlioblastomaGlioblastoma Multiforme+2 more
Kintara Therapeutics, Inc. 29
Testing effectiveness (Phase 2)UnknownNCT02928575
What this trial is testing

Combining Sunitinib, Temozolomide and Radiation to Treat Patients Diagnosed With Glioblastoma

Who this might be right for
Glioblastoma Multiforme
Bassam Abdulkarim 45
Early research (Phase 1)WithdrawnNCT04741984
What this trial is testing

Monocyte Antigen Carrier Cells for Newly Diagnosed GBM

Who this might be right for
GlioblastomaGlioma, Malignant
Michael Gunn
Early research (Phase 1)Not Yet RecruitingNCT07739017
What this trial is testing

OLIG2 Inhibitor CT-179 for Recurrent and Newly-diagnosed Glioblastoma

Who this might be right for
Recurrent GlioblastomaNewly Diagnosed MGMT Unmethylated Glioblastoma
Olivia Newton-John Cancer Research Institute 54
Testing effectiveness (Phase 2)Looking for participantsNCT07326566
What this trial is testing

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Who this might be right for
Glioblastoma (GBM)Newly Diagnosed GlioblastomaGBM+4 more
Black Diamond Therapeutics, Inc. 162
Early research (Phase 1)Active Not RecruitingNCT05743595
What this trial is testing

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Who this might be right for
Unmethylated Glioblastoma
Washington University School of Medicine 27
Large-scale testing (Phase 3)Looking for participantsNCT03970447
What this trial is testing

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Who this might be right for
Glioblastoma
Global Coalition for Adaptive Research 2,250
Early research (Phase 1)Study completedNCT05938387
What this trial is testing

Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or Astrocytoma

Who this might be right for
Glioblastoma
CureVac 37
Large-scale testing (Phase 3)Study completedNCT04396860
What this trial is testing

Testing the Use of the Immunotherapy Drugs Ipilimumab and Nivolumab Plus Radiation Therapy Compared to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed MGMT Unmethylated Glioblastoma

Who this might be right for
GliosarcomaMGMT-Unmethylated Glioblastoma
National Cancer Institute (NCI) 159
Testing effectiveness (Phase 2)UnknownNCT06186440
What this trial is testing

Cisplatin Plus Temozolomide Compared With Temozolomide in Patients With MGMT Promotor Unmethylated Glioblastoma

Who this might be right for
Glioblastoma Multiforme of Brain
Zhongnan Hospital 60
Testing effectiveness (Phase 2)Study completedNCT00813943
What this trial is testing

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status

Who this might be right for
Glioblastoma
EMD Serono 265
Very early researchStudy completedNCT05432375
What this trial is testing

Study of Tinostamustine for Adjuvant Treatment of Glioblastoma

Who this might be right for
Glioblastoma Multiforme
Mundipharma Research Limited 10
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