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Results for “Newly Diagnosed MGMT Unmethylated Glioblastoma”

34 trials

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Showing 20 of 34 results

Early research (Phase 1)Ended earlyNCT03250299
What this trial is testing

Microtubule-Targeted Agent BAL101553 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Who this might be right for
GlioblastomaMGMT-Unmethylated Glioblastoma
Basilea Pharmaceutica 26
Testing effectiveness (Phase 2)Looking for participantsNCT07185880
What this trial is testing

The Safety and Tolerability of MT-125 in GBM Patients

Who this might be right for
Glioblastoma (GBM)
Myosin Therapeutics Inc. 36
Testing effectiveness (Phase 2)Looking for participantsNCT06504381
What this trial is testing

DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

Who this might be right for
High Grade GliomaMGMT-Unmethylated GlioblastomaMGMT-Methylated Glioblastoma
University of California, San Francisco 70
Testing effectiveness (Phase 2)Ended earlyNCT01044225
What this trial is testing

Effect of Radiation Therapy Plus Temozolomide Combined With Cilengitide or Cetuximab on the 1-year Overall Survival of Patients With Newly Diagnosed MGMT-promoter Unmethylated Glioblastoma

Who this might be right for
Glioblastoma
Bart Neyns 12
Testing effectiveness (Phase 2)Study completedNCT03367715
What this trial is testing

Nivolumab, Ipilimumab, and Short-course Radiotherapy in Adults With Newly Diagnosed, MGMT Unmethylated Glioblastoma

Who this might be right for
MGMT-unmethylated Glioblastoma (GBM)GBM
NYU Langone Health 10
Large-scale testing (Phase 3)Not Yet RecruitingNCT07452458
What this trial is testing

Temporally-Modulated Pulsed Radiation Therapy Versus Standard Radiation Therapy for the Treatment of Newly Diagnosed, IDH Wildtype, MGMT-Unmethylated Glioblastoma

Who this might be right for
Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma
NRG Oncology 398
Early research (Phase 1)Study completedNCT05938387
What this trial is testing

Safety and Tolerability of CVGBM in Adults With Newly Diagnosed MGMT-Unmethylated Glioblastoma or Astrocytoma

Who this might be right for
Glioblastoma
CureVac 37
Very early researchStudy completedNCT05432375
What this trial is testing

Study of Tinostamustine for Adjuvant Treatment of Glioblastoma

Who this might be right for
Glioblastoma Multiforme
Mundipharma Research Limited 10
Testing effectiveness (Phase 2)Ended earlyNCT06359379
What this trial is testing

Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter

Who this might be right for
Glioblastoma, IDH-wildtype
Shuttle Pharmaceuticals, Inc. 30
Early research (Phase 1)Ended earlyNCT03107780
What this trial is testing

Testing the Ability of AMG 232 (KRT 232) to Get Into the Tumor in Patients With Brain Cancer

Who this might be right for
GlioblastomaGliosarcomaMGMT-Unmethylated Glioblastoma+1 more
National Cancer Institute (NCI) 32
Early research (Phase 1)Study completedNCT03726515
What this trial is testing

CART-EGFRvIII + Pembrolizumab in GBM

Who this might be right for
Glioblastoma
University of Pennsylvania 7
Testing effectiveness (Phase 2)Looking for participantsNCT05734560
What this trial is testing

D2C7-IT and 2141-V11 in Newly Diagnosed GBM Patients

Who this might be right for
Newly Diagnosed MGMT Unmethylated Glioblastoma
Darell Bigner 50
Early research (Phase 1)Active Not RecruitingNCT05743595
What this trial is testing

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Who this might be right for
Unmethylated Glioblastoma
Washington University School of Medicine 27
Testing effectiveness (Phase 2)UnknownNCT04224441
What this trial is testing

Repurposing Chlorpromazine in the Treatment of Glioblastoma

Who this might be right for
Glioblastoma MultiformeMGMT-Unmethylated Glioblastoma
Marco G Paggi, MD, PhD 41
Large-scale testing (Phase 3)Looking for participantsNCT03970447
What this trial is testing

A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

Who this might be right for
Glioblastoma
Global Coalition for Adaptive Research 2,250
Testing effectiveness (Phase 2)Looking for participantsNCT07476794
What this trial is testing

Daily Temozolomide for Elderly Patients With Unmethylated MGMT- Promoter Newly Diagnosed GliOblatoma

Who this might be right for
Glioblastoma
Sunnybrook Health Sciences Centre 118
Testing effectiveness (Phase 2)Study completedNCT03050736
What this trial is testing

Safety Study of VAL-083 and Radiotherapy in Patients With Newly Diagnosed GBM Having Unmethylated MGMT Expression

Who this might be right for
GliomaGlioblastomaGlioblastoma Multiforme+2 more
Kintara Therapeutics, Inc. 29
Testing effectiveness (Phase 2)Study completedNCT00813943
What this trial is testing

Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Unmethylated Gene Promoter Status

Who this might be right for
Glioblastoma
EMD Serono 265
Large-scale testing (Phase 3)Looking for participantsNCT06388733
What this trial is testing

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Who this might be right for
GlioblastomaGBMBrain Neoplasms, Adult, Malignant+1 more
Ivy Brain Tumor Center 450
Testing effectiveness (Phase 2)Looking for participantsNCT05879250
What this trial is testing

WP1066 and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma

Who this might be right for
Glioblastoma, IDH-WildtypeMGMT-Unmethylated Glioblastoma
Northwestern University 39
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