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Results for “Newly-diagnosed Ph+ Acute Lymphoblastic Leukemia”

64 trials

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Showing 20 of 64 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT01920737
What this trial is testing

A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Memorial Sloan Kettering Cancer Center 39
Large-scale testing (Phase 3)Active Not RecruitingNCT02883049
What this trial is testing

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

Who this might be right for
B Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, BCR-ABL1-LikeCentral Nervous System Leukemia+1 more
National Cancer Institute (NCI) 5,949
Testing effectiveness (Phase 2)Ended earlyNCT04554459
What this trial is testing

Ponatinib Plus Reduced-intensity Chemotherapy in the First-line Treatment of Adult Patients With Ph+ ALL

Who this might be right for
Acute Lymphoblastic Leukemia, AdultPh+ ALLNewly Diagnosed
Institute of Hematology and Blood Transfusion, Czech Republic 4
Testing effectiveness (Phase 2)Looking for participantsNCT06578546
What this trial is testing

Chemotherapy-free Regimen of Venetoclax, Azacitidine Plus Orebatinib (VAO Regimen) for Newly Diagnosed ph+ALL

Who this might be right for
Ph-Positive Acute Lymphoblastic Leukemia
The First Affiliated Hospital of Soochow University 30
Testing effectiveness (Phase 2)UnknownNCT02776605
What this trial is testing

Ponatinib With Chemotherapy for Young Adults Ph Positive Acute Lymphoblastic Leukemia

Who this might be right for
ALL
PETHEMA Foundation 30
Large-scale testing (Phase 3)Active Not RecruitingNCT02003222
What this trial is testing

Combination Chemotherapy With or Without Blinatumomab in Treating Patients With Newly Diagnosed BCR-ABL-Negative B Lineage Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative
National Cancer Institute (NCI) 488
Testing effectiveness (Phase 2)Looking for participantsNCT06082934
What this trial is testing

Olverembatinib Plus Venetoclax and Dexamethasone for Treatment-naïve Ph+ Acute Lymphoblastic Leukemia

Who this might be right for
Newly-diagnosed Ph+ Acute Lymphoblastic Leukemia
Xijing Hospital 30
Testing effectiveness (Phase 2)Study completedNCT01256398
What this trial is testing

Dasatinib Followed by Stem Cell Transplant in Treating Older Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaAdult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1
National Cancer Institute (NCI) 66
Testing effectiveness (Phase 2)Study completedNCT04788472
What this trial is testing

Sequential CD19 and CD22 CAR-T Therapy for Newly Diagnosed Ph+ B-ALL

Who this might be right for
B-Cell Acute Lymphoblastic Leukemia, Adult
Zhejiang University 28
Not applicableNot Yet RecruitingNCT06649422
What this trial is testing

Reduced-Dose Chemo Followed by 14 Days of Blinatumomab for Newly Diagnosed Adult B-ALL Patients: a Multicenter Study

Who this might be right for
Leukemia, Lymphocytic, Acute, Adult
Shandong University 36
Not applicableNot Yet RecruitingNCT07493161
What this trial is testing

Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL

Who this might be right for
Ph+ ALL
Institute of Hematology & Blood Diseases Hospital, China 100
Large-scale testing (Phase 3)Looking for participantsNCT07152041
What this trial is testing

Newly-diagnosed Pediatric Ph-positive B-ALL Protocol

Who this might be right for
Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+)Childhood Leukemia, Acute Lymphoblastic
Institute of Hematology & Blood Diseases Hospital, China 150
Testing effectiveness (Phase 2)UnknownNCT01005758
What this trial is testing

Combination Chemotherapy in Treating Adult Patients With Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Ohio State University Comprehensive Cancer Center 180
Not applicableUnknownNCT05024357
What this trial is testing

TKI Maintenance Therapy Following Allo-HSCT in Newly Diagnosed Ph+ Adult ALL

Who this might be right for
Precursor Cell Lymphoblastic Leukemia-LymphomaPhiladelphia-Positive Acute Lymphoblastic LeukemiaALL, Adult
First Affiliated Hospital Xi'an Jiaotong University 80
Testing effectiveness (Phase 2)Looking for participantsNCT07224100
What this trial is testing

Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma

Who this might be right for
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1B Lymphoblastic Leukemia/Lymphoma With t(9;22)(q34.1;q11.2); BCR-ABL1Lymphoblastic Lymphoma
University of Washington 33
Early research (Phase 1)Looking for participantsNCT05157971
What this trial is testing

Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic LeukemiaPh-Like Acute Lymphoblastic Leukemia
City of Hope Medical Center 24
Large-scale testing (Phase 3)Looking for participantsNCT06051409
What this trial is testing

Olverembatinib in Patients With Newly Diagnosed Ph+ALL.

Who this might be right for
Ph+ ALL
Ascentage Pharma Group Inc. 350
Testing effectiveness (Phase 2)UnknownNCT06078306
What this trial is testing

CD19CD22 CAR-T Therapy in Patients With High-Risk B Acute Lymphoblastic Leukemia (B-ALL).

Who this might be right for
B Acute Lymphoblastic LeukemiaPh-Negative ALLHigh Risk Acute Lymphoblastic Leukemia
The First Affiliated Hospital of Soochow University 20
Large-scale testing (Phase 3)Looking for participantsNCT04994717
What this trial is testing

Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults With Newly Diagnosed Philadelphia-negative B-cell Precursor Acute Lymphoblastic Leukemia

Who this might be right for
Newly Diagnosed Philadelphia (Ph)-Negative B-cell Precursor Acute Lymphoblastic Leukemia (ALL)
Amgen 304
Testing effectiveness (Phase 2)Study completedNCT01004497
What this trial is testing

First-line Dasatinib Plus Conventional Chemotherapy in Adults With Newly Diagnosed Ph-Positive ALL

Who this might be right for
Acute Lymphoblastic Leukemia
The Catholic University of Korea 51
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