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Results for “Newly-diagnosed Ph+ Acute Lymphoblastic Leukemia”

68 trials

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Showing 20 of 68 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT02143414
What this trial is testing

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaB Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1+2 more
National Cancer Institute (NCI) 53
Early research (Phase 1)Not Yet RecruitingNCT07614022
What this trial is testing

LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL)

Who this might be right for
Philadelphia Positive Acute Lymphoblastic Leukemia
Wake Forest University Health Sciences 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT01920737
What this trial is testing

A Novel "Pediatric-Inspired" Regimen With Reduced Myelosuppressive Drugs for Adults (Aged 18-60) With Newly Diagnosed Ph Negative Acute Lymphoblastic Leukemia

Who this might be right for
Leukemia
Memorial Sloan Kettering Cancer Center 39
Testing effectiveness (Phase 2)WithdrawnNCT01670084
What this trial is testing

Nilotinib and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia

Who this might be right for
B-cell Adult Acute Lymphoblastic LeukemiaBlastic Phase Chronic Myelogenous LeukemiaChronic Myelogenous Leukemia, BCR-ABL1 Positive+2 more
Mayo Clinic
Testing effectiveness (Phase 2)Study completedNCT05557110
What this trial is testing

Reduced-dose Chemotherapy Followed by Blinatumomab in Induction Therapy of Newly Diagnosed Non-elderly Ph-B-ALL

Who this might be right for
B Acute Lymphoblastic Leukemia
Chen Suning 35
Post-approval studies (Phase 4)UnknownNCT02690922
What this trial is testing

Low-dose Chemotherapy Combine With Tyrosine Kinase Inhibitor to Treat ph+ Acute Lymphoblastic Leukemia Patients

Who this might be right for
ph+ Acute Lymphoblastic Leukemia
Tongji Hospital 40
Testing effectiveness (Phase 2)Looking for participantsNCT06250959
What this trial is testing

RDC-Blinatumomab Versus hyperCVAD for Ph-negative B-ALL.

Who this might be right for
ALL, AdultPhiladelphia-Negative ALL
Chen Suning 124
Testing effectiveness (Phase 2)Looking for participantsNCT06738368
What this trial is testing

Etoposide, Prednisone, Vincristine, Cyclophosphamide, and Doxorubicin (DA-EPOCH) With or Without Rituximab Plus Recombinant Erwinia Asparaginase (JZP458) for the Treatment of Newly Diagnosed Ph Negative B-Acute Lymphoblastic Leukemia or T Acute Lymphoblastic Leukemia

Who this might be right for
B Acute Lymphoblastic Leukemia, Philadelphia Chromosome NegativeT Acute Lymphoblastic Leukemia
University of Washington 30
Post-approval studies (Phase 4)Ended earlyNCT05071482
What this trial is testing

Flumatinib Versus Imatinib Combined With Chemotherapy for de Novo Ph+ ALL

Who this might be right for
Acute Leukemia
Institute of Hematology & Blood Diseases Hospital, China 39
Testing effectiveness (Phase 2)UnknownNCT06578546
What this trial is testing

Chemotherapy-free Regimen of Venetoclax, Azacitidine Plus Orebatinib (VAO Regimen) for Newly Diagnosed ph+ALL

Who this might be right for
Ph-Positive Acute Lymphoblastic Leukemia
The First Affiliated Hospital of Soochow University 30
Early research (Phase 1)Study completedNCT01132573
What this trial is testing

Entinostat and Clofarabine in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Poor-Risk Acute Lymphoblastic Leukemia or Bilineage/Biphenotypic Leukemia

Who this might be right for
Acute Leukemias of Ambiguous LineagePhiladelphia Chromosome Negative Adult Precursor Acute Lymphoblastic LeukemiaRecurrent Adult Acute Lymphoblastic Leukemia+1 more
National Cancer Institute (NCI) 27
Large-scale testing (Phase 3)Not Yet RecruitingNCT07223190
What this trial is testing

A Study Evaluating Subcutaneous Versus Intravenous Blinatumomab in Newly Diagnosed Adults With B-cell Precursor Acute Lymphoblastic Leukaemia

Who this might be right for
Philadelphia Chromosome Negative B-cell Precursor Acute Lymphoblastic Leukemia
Amgen 560
Large-scale testing (Phase 3)Active Not RecruitingNCT03007147
What this trial is testing

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Who this might be right for
Acute Lymphoblastic LeukemiaB Acute Lymphoblastic LeukemiaMixed Phenotype Acute Leukemia+1 more
Children's Oncology Group 352
Testing effectiveness (Phase 2)Study completedNCT03480438
What this trial is testing

Treatment of Older Patients With B-precursor ALL With Sequential Dose Reduced Chemotherapy and Blinatumomab

Who this might be right for
B-Precursor ALL
Goethe University 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06930105
What this trial is testing

Impact of Low-intensity Chemotherapy Combined With Short-course Blinatumomab on Allo-HSCT in Adults With Ph- B-ALL

Who this might be right for
Acute Lymphoid Leukemia (ALL)
Xianmin Song, MD 45
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06773936
What this trial is testing

Adding Asciminib to Usual Treatment for Adults With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Acute Lymphoblastic Leukemia

Who this might be right for
Philadelphia Chromosome Positive Acute Lymphoblastic LeukemiaCD19+ Acute Leukemia
SWOG Cancer Research Network 55
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07643103
What this trial is testing

Immuno-Targeted Therapy Plus Low-Dose Chemotherapy for Newly Diagnosed Adult Ph-Negative B-ALL: A Prospective Umbrella Trial

Who this might be right for
Ph- Acute Lymphoblastic Leukemia (Ph-ALL)
Institute of Hematology & Blood Diseases Hospital, China 32
Testing effectiveness (Phase 2)Looking for participantsNCT06387121
What this trial is testing

Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Adult Ph- B-ALL

Who this might be right for
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Institute of Hematology & Blood Diseases Hospital, China 53
Testing effectiveness (Phase 2)Study completedNCT05433532
What this trial is testing

Study of Azacitidine，Venetoclax，and Flumatinib in Newly Diagnosed Ph-positive Acute Leukemia and CML-AP/BP Patients

Who this might be right for
Philadelphia ChromosomeAcute Myeloid LeukemiaAcute Lymphoblastic Leukemia+2 more
The First Affiliated Hospital of Soochow University 20
Not applicableStudy completedNCT01085617
What this trial is testing

Standard Chemotherapy with or Without Nelarabine or Rituximab in Treating Patients with Newly Diagnosed Acute Lymphoblastic Leukemia

Who this might be right for
LeukemiaMucositisOral Complications
University College, London
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