Not applicableStudy completedNCT02348385What this trial is testingImaging Extrastriatal Dopamine Release in Tobacco Smokers and NonsmokersWho this might be right forNicotine Dependence Yale University 49
Not applicableStudy completedNCT06413797What this trial is testingLittle Cigar and Cigarillo Warnings for YouthWho this might be right forLittle Cigars and Cigarillos (LCC) Use UNC Lineberger Comprehensive Cancer Center 928
Testing effectiveness (Phase 2)Looking for participantsNCT07322432What this trial is testingThe CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette ReductionWho this might be right forAddiction Nicotine VapeAway 70
Not applicableStudy completedNCT04646174What this trial is testingAddressing Psychological Risk Factors Underlying Smoking Persistence in COPD Patients: The Fresh Start-II StudyWho this might be right forCopdSmoking CessationNicotine Dependence+2 more Rush University Medical Center 66
Post-approval studies (Phase 4)Active Not RecruitingNCT05206435What this trial is testingMethadone-Maintained Smokers Switching to E-CigarettesWho this might be right forNicotine DependenceElectronic Cigarette Use Butler Hospital 240
Not applicableStudy completedNCT03839745What this trial is testingShort-Term Cardiovascular Effects of E-Cigarettes: Influence of Device PowerWho this might be right forCardiovascular Risk FactorNicotine Dependence University of California, San Francisco 16
Not applicableStudy completedNCT01627392What this trial is testingMechanisms of the Nicotine Metabolism Effect on Tobacco DependenceWho this might be right forCigarette Smoking University of California, San Francisco 305
Testing effectiveness (Phase 2)Study completedNCT01592695What this trial is testingTailored Tobacco Quitline for Rural VeteransWho this might be right forCigarette Smoking Iowa City Veterans Affairs Medical Center 63
Early research (Phase 1)Study completedNCT00969137What this trial is testingSensitivity to Intravenous Nicotine: Genetic ModeratorsWho this might be right forNicotine Dependence Yale University 213
Post-approval studies (Phase 4)Looking for participantsNCT06688539What this trial is testingE-cigarette Cessation in Adults Who Co-use CannabisWho this might be right forNicotine DependenceTobacco Use Disorder Medical University of South Carolina 105
Testing effectiveness (Phase 2)Study completedNCT02250664What this trial is testingProject 2, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in Opioid AbusersWho this might be right forTobacco Use Disorder University of Vermont 775
Not applicableStudy completedNCT02102100What this trial is testingThe Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco UsersWho this might be right forNicotine Dependence Yale University 57
Not applicableNot Yet RecruitingNCT06909500What this trial is testingA Digital Intervention (ACT on Vaping App) for Vaping Cessation in Young Adult E-Cigarette UsersWho this might be right forNicotine DependenceTobacco-Related Carcinoma Fred Hutchinson Cancer Center 1,372
Not applicableStudy completedNCT01523730What this trial is testingEffects of rTMS on Cigarette Smoking and Cognition in SchizophreniaWho this might be right forSchizophreniaNicotine Addiction Centre for Addiction and Mental Health 27
Not applicableStudy completedNCT03904186What this trial is testingEffectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIVWho this might be right forHuman Immunodeficiency VirusSmoking CessationSmoking, Cigarette+4 more Massachusetts General Hospital 131
Testing effectiveness (Phase 2)Looking for participantsNCT07040566What this trial is testingA Trial of Varenicline for E-cigarette CessationWho this might be right forE-cigarette UseVapingNicotine Dependence Yale University 326
Not applicableLooking for participantsNCT02974582What this trial is testingUnderstanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult SmokersWho this might be right forNicotine Dependence National Institute on Minority Health and Health Disparities (NIMHD) 530
Not applicableEnded earlyNCT01411007What this trial is testingThe Impact of Real-time Functional Magnetic Resonance Imaging (fMRI) Feedback on Response to Nicotine CuesWho this might be right forNicotine Dependence Medical University of South Carolina 44
Post-approval studies (Phase 4)Looking for participantsNCT05587361What this trial is testingBeta-Adrenergic Modulation of Drug Cue ReactivityWho this might be right forTobacco Use DisorderNicotine DependenceCigarette Smoking University of Oklahoma 80
Testing effectiveness (Phase 2)Study completedNCT01989507What this trial is testingVery Low-Nicotine Cigarettes in Smokers With SUDWho this might be right forNicotine Dependence Brown University 250