Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Nicotine Use”

977 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 977 results

Testing effectiveness (Phase 2)Study completedNCT00664755
What this trial is testing

Menstrual Cycle Effects on Smoking Cessation and Cue Reactivity

Who this might be right for
Nicotine Dependence
Medical University of South Carolina 140
Not applicableStudy completedNCT01304810
What this trial is testing

A Follow-up Study to Assess Long-term Immunogenicity and Safety of NicVAX/Placebo as an Aid to Smoking Cessation

Who this might be right for
Smoking CessationNicotine Dependence
Nabi Biopharmaceuticals 300
Not applicableEnded earlyNCT07172438
What this trial is testing

A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers

Who this might be right for
SmokingTobacco
RAI Services Company 668
Not applicableLooking for participantsNCT07594717
What this trial is testing

Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder

Who this might be right for
Nicotine Use DisoderOpioid Use Disorder
Prisma Health-Upstate 70
Not applicableStudy completedNCT00267813
What this trial is testing

The Effects of Craving and Abstinence From Cigarettes on Brain Metabolism in Smokers

Who this might be right for
Nicotine Dependence
Tel-Aviv Sourasky Medical Center 24
Not applicableStudy completedNCT04123041
What this trial is testing

Characterize the Nicotine Uptake and Subjective Effects With Use of JUUL Electronic Nicotine Delivery Systems

Who this might be right for
Electronic Cigarette UseTobacco Smoking
Juul Labs, Inc. 137
Not applicableLooking for participantsNCT06552741
What this trial is testing

Screening, Evaluation and Assessment (SEA) Protocol at the NIDA IRP

Who this might be right for
Substance Use DisorderAlcohol Use Disorder
National Institute on Drug Abuse (NIDA) 10,000
Testing effectiveness (Phase 2)Study completedNCT00218296
What this trial is testing

Comparison Across Treatment Conditions to Reduce Smokeless Tobacco Use

Who this might be right for
Tobacco Use Disorder
University of Minnesota 332
Not applicableStudy completedNCT01202942
What this trial is testing

Use and Harm Exposure in New Low Nicotine Cigarettes

Who this might be right for
Cigarette Smoking
University of Pennsylvania 246
Testing effectiveness (Phase 2)Looking for participantsNCT07040566
What this trial is testing

A Trial of Varenicline for E-cigarette Cessation

Who this might be right for
E-cigarette UseVapingNicotine Dependence
Yale University 326
Not applicableStudy completedNCT03993769
What this trial is testing

CSD190101: A Study to Assess Nicotine Pharmacokinetic Parameters After Use of Two Smokeless Tobacco Products

Who this might be right for
Tobacco Use
RAI Services Company 64
Early research (Phase 1)Study completedNCT03543137
What this trial is testing

To Assess the Bioequivalence of the 4mg Prototype Mini Nicotine Lozenge to the Reference Product (Nicorette) in Healthy Smokers

Who this might be right for
Tobacco Use Disorder
GlaxoSmithKline 37
Not applicableLooking for participantsNCT06909500
What this trial is testing

A Digital Intervention (ACT on Vaping App) for Vaping Cessation in Young Adult E-Cigarette Users

Who this might be right for
Nicotine DependenceTobacco-Related Carcinoma
Fred Hutchinson Cancer Center 1,178
Not applicableEnded earlyNCT01492322
What this trial is testing

SPECT Imaging of DAT Genotype

Who this might be right for
Nicotine Withdrawal
University of Pennsylvania 14
Large-scale testing (Phase 3)Active Not RecruitingNCT04176172
What this trial is testing

Optimizing Tobacco Use Treatment for PLWHA

Who this might be right for
HIV/AIDSNicotine Dependence
University of Pennsylvania 340
Large-scale testing (Phase 3)Study completedNCT00110630
What this trial is testing

Smoking Treatment of Prisoners

Who this might be right for
Tobacco Use CessationTobacco Use Disorder
National Institute on Drug Abuse (NIDA) 250
Not applicableStudy completedNCT04461288
What this trial is testing

Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment

Who this might be right for
Smoking CessationNicotine DependenceTobacco Use+1 more
University of California, San Francisco 121
Not applicableStudy completedNCT02210754
What this trial is testing

Characterization of Nicotine Exposure and Urge-to-Smoke Following Use of Electronic and Conventional Cigarettes

Who this might be right for
Smoking
Lorillard Tobacco Company 24
Post-approval studies (Phase 4)Not Yet RecruitingNCT07328594
What this trial is testing

Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking

Who this might be right for
SmokingNicotineTobacco+4 more
Legacy Health System 44
Not applicableStudy completedNCT00756275
What this trial is testing

Varenicline and Motivational Advice for Smokers With Substance Use Disorders

Who this might be right for
Smoking CessationNicotine Dependence
Brown University 158
Load More Results