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Results for “Non-Langerhans-Cell Histiocytosis”

222 trials

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Showing 20 of 222 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04320888
What this trial is testing

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Who this might be right for
Hematopoietic and Lymphatic System NeoplasmRecurrent EpendymomaRecurrent Ewing Sarcoma+35 more
National Cancer Institute (NCI) 1
Testing effectiveness (Phase 2)Active Not RecruitingNCT01821781
What this trial is testing

Immune Disorder HSCT Protocol

Who this might be right for
Immune Deficiency DisordersSevere Combined ImmunodeficiencyChronic Granulomatous Disease+11 more
Washington University School of Medicine 20
Not applicableStudy completedNCT01490801
What this trial is testing

Biomarkers in Blood and Tissue Samples From Patients With Epstein-Barr Virus-Positive Hodgkin Lymphoma

Who this might be right for
LymphomaNonneoplastic Condition
Children's Oncology Group 50
Testing effectiveness (Phase 2)Study completedNCT00176865
What this trial is testing

Stem Cell Transplant for Immunologic or Histiocytic Disorders

Who this might be right for
Hemophagocytic LymphohistiocytosisX-Linked Lymphoproliferative DisordersChediak-Higashi Syndrome+3 more
Masonic Cancer Center, University of Minnesota 19
Not applicableActive Not RecruitingNCT03827343
What this trial is testing

Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer

Who this might be right for
Macrophage Activation SyndromePrimary Hemophagocytic Lymphohistiocytosis
National Cancer Institute (NCI) 500
Testing effectiveness (Phase 2)Study completedNCT03526250
What this trial is testing

Palbociclib in Treating Patients With Relapsed or Refractory Rb Positive Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating Alterations in Cell Cycle Genes (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Ewing Sarcoma+29 more
National Cancer Institute (NCI) 23
Large-scale testing (Phase 3)Study completedNCT01371825
What this trial is testing

Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of Sebelipase Alfa in Children With Growth Failure Due to Lysosomal Acid Lipase Deficiency

Who this might be right for
Lysosomal Acid Lipase DeficiencyWolman Disease
Alexion Pharmaceuticals, Inc. 9
Large-scale testing (Phase 3)Ended earlyNCT03879655
What this trial is testing

Open-label Study of VTS-270 in Participants With Neurologic Manifestations of Niemann-Pick Type C1

Who this might be right for
Niemann-Pick Disease, Type C
Mandos LLC 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT03210714
What this trial is testing

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmRecurrent Childhood EpendymomaRecurrent Childhood Malignant Germ Cell Tumor+29 more
National Cancer Institute (NCI) 20
Large-scale testing (Phase 3)Not Yet RecruitingNCT07626398
What this trial is testing

All-Trans Retinoic Acid for the Treatment of Hemophagocytic Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis (HLH)
Beijing Anzhen Hospital 30
Not applicableLooking for participantsNCT06614998
What this trial is testing

Establishment of an Early Warning Screening System for Hemophagocytic Lymphohistiocytosis a Multi-center, Prospective Study

Who this might be right for
Hemophagocytic Syndrome
The Affiliated Hospital of Xuzhou Medical University 80
Very early researchUnknownNCT05353179
What this trial is testing

Study on Pharmacokinetics of Meperizumab Injection and NUCALA® in Healthy Male Volunteers

Who this might be right for
Granulomatosis With PolyangiitisHemophagocytic Syndrome
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 88
Not applicableUnknownNCT04500886
What this trial is testing

Evaluate the Efficacy and Safety of PEG-rhG-CSF in Patients With Hemophagocytic Syndrome

Who this might be right for
Hemophagocytic Syndrome
CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. 50
Not applicableUnknownNCT06332183
What this trial is testing

GWAS and EWAS in Patients With Erdheim-Chester Disease

Who this might be right for
Erdheim-Chester Disease
Augusto Vaglio 300
Large-scale testing (Phase 3)UnknownNCT04077905
What this trial is testing

Pegylated Liposomal Doxorubicin as a Induction Therapy for Lymphoma Induced Hemophagocytic Lymphohistiocytosis.

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 160
Not applicableNot Yet RecruitingNCT06131489
What this trial is testing

Segmental Resection Combined With DEP Regimen for EBV-HLH Patients With Intestinal Involvement

Who this might be right for
Hemophagocytic LymphohistiocytosisEpstein-Barr VirusBowel Resection
Beijing Friendship Hospital 20
Not applicableUnknownNCT05164978
What this trial is testing

DEP Combine With PD-1 Antibody as an Treatment for EBV-HLH

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 20
Post-approval studies (Phase 4)Study completedNCT03910621
What this trial is testing

Safety and Efficacy of Miglustat in Chinese NPC Patients

Who this might be right for
Niemann-Pick Disease, Type C
Actelion 17
Not applicableLooking for participantsNCT05277272
What this trial is testing

INTO-HLH: A Disease Registry for Patients With Hemophagocytic Lymphohistiocytosis (HLH)

Who this might be right for
Hemophagocytic Lymphohistiocytoses
Children's Hospital Medical Center, Cincinnati 200
Testing effectiveness (Phase 2)Study completedNCT03096782
What this trial is testing

Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or Lymphoma

Who this might be right for
Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveAcute Biphenotypic LeukemiaAcute Leukemia+19 more
M.D. Anderson Cancer Center 6
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