Large-scale testing (Phase 3)Study completedNCT00538850What this trial is testingFentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer PainWho this might be right forCancer INSYS Therapeutics Inc 130
Testing effectiveness (Phase 2)Active Not RecruitingNCT03899792What this trial is testingOral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) TumorsWho this might be right forMedullary Thyroid CancerInfantile MyofibromatosisInfantile Fibrosarcoma+2 more Eli Lilly and Company 36
Testing effectiveness (Phase 2)Looking for participantsNCT06051695What this trial is testingEvaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 ExpressionWho this might be right forSolid Tumor, AdultColorectal CancerNSCLC+17 more A2 Biotherapeutics Inc. 474
Early research (Phase 1)Looking for participantsNCT06756035What this trial is testingCT-95 in Advanced Cancers Associated With Mesothelin ExpressionWho this might be right forMesothelin-Expressing TumorsEpithelial Ovarian CancerMalignant Pleural Mesothelioma, Advanced+8 more Context Therapeutics Inc. 70
Testing effectiveness (Phase 2)Ended earlyNCT05451849What this trial is testingA Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing CancerWho this might be right forMesotheliomaMesotheliomas PleuralMesothelioma, Malignant+14 more TCR2 Therapeutics 14
Testing effectiveness (Phase 2)Active Not RecruitingNCT03907852What this trial is testingPhase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing CancerWho this might be right forMesotheliomaMesothelioma, MalignantMesothelioma; Pleura+8 more TCR2 Therapeutics 57
Early research (Phase 1)Active Not RecruitingNCT05215574What this trial is testingStudy of NGM831 as Monotherapy and in Combination With Pembrolizumab or Pembrolizumab and NGM438 in Advanced or Metastatic Solid TumorsWho this might be right forPancreatic CancerBreast CancerGastric Cancer+13 more NGM Biopharmaceuticals, Inc 130
Early research (Phase 1)Active Not RecruitingNCT05544929What this trial is testingSafety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersWho this might be right forCarcinoma, Non-Small-Cell LungCutaneous MelanomaCarcinoma, Renal Cell+9 more Novartis Pharmaceuticals 126
Not applicableWithdrawnNCT01325753What this trial is testingCryotherapy in Treating Patients With Lung Cancer That Has Spread to the Other Lung or Parts of the BodyWho this might be right forAdvanced Malignant MesotheliomaExtensive Stage Small Cell Lung CancerLung Metastases+4 more Wake Forest University Health Sciences
Early research (Phase 1)UnknownNCT02637531What this trial is testingA Dose-Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IPI-549Who this might be right forAdvanced Solid Tumors (Part A/B/C/D)Non-small Cell Lung Cancer (Part E)Melanoma (Part E)+5 more Infinity Pharmaceuticals, Inc. 219
Testing effectiveness (Phase 2)Looking for participantsNCT03556228What this trial is testingVMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or LymphomaWho this might be right forHead and Neck CarcinomaAdenoid Cystic CarcinomaLung Cancer+22 more VM Oncology, LLC 242
Early research (Phase 1)Active Not RecruitingNCT04491942What this trial is testingTesting the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial CancerWho this might be right forAdvanced Bile Duct CarcinomaAdvanced Breast CarcinomaAdvanced Cervical Carcinoma+31 more National Cancer Institute (NCI) 74
Testing effectiveness (Phase 2)Looking for participantsNCT04104776What this trial is testingTulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and LymphomasWho this might be right forAdvanced Solid TumorDiffuse Large B Cell LymphomaLymphoma, T-Cell+5 more Novartis Pharmaceuticals 300
Early research (Phase 1)Study completedNCT03507452What this trial is testingFirst-in-human Study of BAY2287411 Injection, a Thorium-227 Labeled Antibody-chelator Conjugate, in Patients With Tumors Known to Express MesothelinWho this might be right forAdvanced Recurrent Malignant Pleural Epithelioid MesotheliomaAdvanced Recurrent Malignant Peritoneal Epithelioid MesotheliomaAdvanced Recurrent Serous Ovarian Cancer+1 more Bayer 36
Testing effectiveness (Phase 2)Looking for participantsNCT05086692What this trial is testingA Beta-only IL-2 ImmunoTherapY StudyWho this might be right forAdvanced Solid TumorUnresectable Solid TumorClear Cell Renal Cell Carcinoma+34 more Medicenna Therapeutics, Inc. 115
Early research (Phase 1)Study completedNCT00066651What this trial is testingImmunotoxin Therapy in Treating Patients With Advanced Solid TumorsWho this might be right forCervical CancerFallopian Tube CancerHead and Neck Cancer+5 more National Cancer Institute (NCI)
Early research (Phase 1)Looking for participantsNCT07705334What this trial is testingSHY-ONC6, a Novel Proteasome Inhibitor, in Adults With Advanced or Metastatic Solid TumorsWho this might be right forAdvanced or Metastatic Solid TumorsTriple Negative Breast Cancer (TNBC)HR+ Breast Cancer+8 more SHY Therapeutics 30
Testing effectiveness (Phase 2)Looking for participantsNCT04969315What this trial is testingTT-4 and TT-10 as Single Agents and in Combination in Subjects With Advanced Selected Solid Tumors and Pleural MesotheliomaWho this might be right forRenal Cell CancerCastrate Resistant Prostate CancerNon Small Cell Lung Cancer+1 more Portage Biotech 35
Testing effectiveness (Phase 2)Ended earlyNCT00281125What this trial is testingPhase I/II Trial of PTK787 and Pemetrexed With or Without Cisplatin for Lung CancerWho this might be right forNon-Small Cell Lung Cancer and Pleural Mesothelioma Nevada Cancer Institute 20
Early research (Phase 1)Ended earlyNCT06336148What this trial is testingA Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid TumorsWho this might be right forSolid Tumor Actym Therapeutics, Inc. 10