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Results for “Non-familial Hypercholesterolemia”

28 trials

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Showing 20 of 28 results

Large-scale testing (Phase 3)Study completedNCT00654602
What this trial is testing

48-wk Open Label Phase IIIb to Evaluate Efficacy and Safety

Who this might be right for
Dyslipidaemia
AstraZeneca 1,500
Large-scale testing (Phase 3)Not Yet RecruitingNCT07421284
What this trial is testing

Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia on a Background of Lipid-lowering Therapy

Who this might be right for
Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 900
Large-scale testing (Phase 3)Study completedNCT04289285
What this trial is testing

Safety and Efficacy of IBI306 in Chinese Subjects With Non-familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 804
Large-scale testing (Phase 3)Not Yet RecruitingNCT07474649
What this trial is testing

Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events

Who this might be right for
Coronary AtherosclerosisMixed DyslipidemiaHypercholesterolemia
Daiichi Sankyo 103
Large-scale testing (Phase 3)Study completedNCT02666664
What this trial is testing

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Diseases
Esperion Therapeutics, Inc. 2,230
Large-scale testing (Phase 3)Study completedNCT05425745
What this trial is testing

Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies.

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia+6 more
NewAmsterdam Pharma 354
Not applicableNot Yet RecruitingNCT07427472
What this trial is testing

"Detection and Follow-up of Coronary Lesions in HeFH (DESTINY-FH Study)"

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Assistance Publique - Hôpitaux de Paris 300
Testing effectiveness (Phase 2)Study completedNCT07421232
What this trial is testing

Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia

Who this might be right for
Hypercholesterolemia and Mixed Hyperlipidemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 156
Large-scale testing (Phase 3)Looking for participantsNCT07614958
What this trial is testing

Phase 3 Clinical Study Evaluating Efficacy, Safety, and Tolerability of Obicetrapib Vs Bempedoic Acid to Treat Dyslipidemia in Adults With Primary Non-familial Hypercholesterolemia or Mixed Dyslipidemia at High to Very High Cardiovascular Risk, During a Treatment Period of Approximately 84 Days

Who this might be right for
Mixed DyslipidemiaHypercholesterolaemia
A. Menarini International Licensing S.A. 426
Large-scale testing (Phase 3)Study completedNCT04885218
What this trial is testing

Efficacy and Safety of SHR-1209 Combined With Lipid-lowering Agents in Patients With Hypercholesterolemia

Who this might be right for
Non-familial HypercholesterolemiaMixed Hyperlipidemia
Jiangsu HengRui Medicine Co., Ltd. 692
Not applicableLooking for participantsNCT07086989
What this trial is testing

Cardiovascular Risk in Children With Chronic Conditions Study

Who this might be right for
Kidney TransplantFamilial HypercholesterolaemiaType 1 Diabetes Mellitus (T1DM)+22 more
Semmelweis University 300
Not applicableStudy completedNCT05218005
What this trial is testing

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia

Who this might be right for
Familial HypercholesterolemiaFamilial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein BFamilial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation+5 more
University of British Columbia 140
Post-approval studies (Phase 4)Ended earlyNCT03694197
What this trial is testing

Long Term Safety Study of PRALUENT

Who this might be right for
Heterozygous Familial HypercholesterolemiaNon-familial Hypercholesterolemia
Regeneron Pharmaceuticals 1,389
Post-approval studies (Phase 4)Study completedNCT02957682
What this trial is testing

Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 2,176
Not applicableEnded earlyNCT02345421
What this trial is testing

Identify and Characterize LAL-D Patients in High-risk Populations

Who this might be right for
Lysosomal Acid Lipase Deficiency
Alexion Pharmaceuticals, Inc. 640
Large-scale testing (Phase 3)Looking for participantsNCT07421297
What this trial is testing

Evaluate the Safety, Efficacy of SYH2053 as Monotherapy in Chinese Participants With Non-familial Hypercholesterolemia or Mixed Hyperlipidemia

Who this might be right for
Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 760
Large-scale testing (Phase 3)Study completedNCT01623115
What this trial is testing

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Who this might be right for
Hypercholesterolemia
Sanofi 486
Large-scale testing (Phase 3)Not Yet RecruitingNCT07444086
What this trial is testing

QLC7401 Monotherapy in Non-familial Hypercholesterolemia or Mixed Dyslipidemia

Who this might be right for
Primary Hypercholesterolemia or Mixed Hyperlipidemia
Qilu Pharmaceutical Co., Ltd. 510
Large-scale testing (Phase 3)Study completedNCT01709500
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 249
Large-scale testing (Phase 3)Looking for participantsNCT07473960
What this trial is testing

IBI306 Monotherapy in Non-Familial Hypercholesterolemia and Mixed Hyperlipidemia

Who this might be right for
Non-Familial Hypercholesterolemia and Mixed Hyperlipidemia
Innovent Biologics (Suzhou) Co. Ltd. 198
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