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Results for “Non-familial Hypercholesterolemia”

28 trials

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Showing 20 of 28 results

Large-scale testing (Phase 3)Study completedNCT02107898
What this trial is testing

Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)

Who this might be right for
Hypercholesterolemia
Sanofi 216
Not applicableEnded earlyNCT02345421
What this trial is testing

Identify and Characterize LAL-D Patients in High-risk Populations

Who this might be right for
Lysosomal Acid Lipase Deficiency
Alexion Pharmaceuticals, Inc. 640
Large-scale testing (Phase 3)Active Not RecruitingNCT07473960
What this trial is testing

IBI306 Monotherapy in Non-Familial Hypercholesterolemia and Mixed Hyperlipidemia

Who this might be right for
Non-Familial Hypercholesterolemia and Mixed Hyperlipidemia
Innovent Biologics (Suzhou) Co. Ltd. 198
Not applicableActive Not RecruitingNCT06331195
What this trial is testing

An Adapted Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Familial Hypercholesterolemia (DICA-FH)

Who this might be right for
Familial Hypercholesterolemia
Hospital do Coracao 300
Not applicableStudy completedNCT05218005
What this trial is testing

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia

Who this might be right for
Familial HypercholesterolemiaFamilial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein BFamilial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation+5 more
University of British Columbia 140
Large-scale testing (Phase 3)Study completedNCT01623115
What this trial is testing

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Who this might be right for
Hypercholesterolemia
Sanofi 486
Not applicableNot Yet RecruitingNCT06675994
What this trial is testing

In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme

Who this might be right for
HealthyHypercholesterolemiaHypertension+6 more
LifeBridge Health 80
Post-approval studies (Phase 4)Study completedNCT02957682
What this trial is testing

Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 2,176
Large-scale testing (Phase 3)Looking for participantsNCT07421297
What this trial is testing

Evaluate the Safety, Efficacy of SYH2053 as Monotherapy in Chinese Participants With Non-familial Hypercholesterolemia or Mixed Hyperlipidemia

Who this might be right for
Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 760
Post-approval studies (Phase 4)Ended earlyNCT03694197
What this trial is testing

Long Term Safety Study of PRALUENT

Who this might be right for
Heterozygous Familial HypercholesterolemiaNon-familial Hypercholesterolemia
Regeneron Pharmaceuticals 1,389
Large-scale testing (Phase 3)Study completedNCT01709500
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 249
Testing effectiveness (Phase 2)Study completedNCT07421232
What this trial is testing

Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia

Who this might be right for
Hypercholesterolemia and Mixed Hyperlipidemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 156
Not applicableLooking for participantsNCT06546137
What this trial is testing

National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry

Who this might be right for
Cardiomyopathy, HypertrophicCardiomyopathy, DilatedCardiomyopathy Restrictive+11 more
Hospital do Coracao 1,211
Large-scale testing (Phase 3)Looking for participantsNCT07614958
What this trial is testing

Phase 3 Clinical Study Evaluating Efficacy, Safety, and Tolerability of Obicetrapib Vs Bempedoic Acid to Treat Dyslipidemia in Adults With Primary Non-familial Hypercholesterolemia or Mixed Dyslipidemia at High to Very High Cardiovascular Risk, During a Treatment Period of Approximately 84 Days

Who this might be right for
Mixed DyslipidemiaHypercholesterolaemia
A. Menarini International Licensing S.A. 426
Large-scale testing (Phase 3)Not Yet RecruitingNCT07474649
What this trial is testing

Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events

Who this might be right for
Coronary AtherosclerosisMixed DyslipidemiaHypercholesterolemia
Daiichi Sankyo 103
Large-scale testing (Phase 3)Not Yet RecruitingNCT07421284
What this trial is testing

Evaluate the Safety, Efficacy of SYH2053 in Chinese Participants With Non-familial Hypercholesterolemia and Mixed Hyperlipidemia on a Background of Lipid-lowering Therapy

Who this might be right for
Non-familial Hypercholesterolemia and Mixed Hyperlipidemia
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. 900
Large-scale testing (Phase 3)Study completedNCT04885218
What this trial is testing

Efficacy and Safety of SHR-1209 Combined With Lipid-lowering Agents in Patients With Hypercholesterolemia

Who this might be right for
Non-familial HypercholesterolemiaMixed Hyperlipidemia
Jiangsu HengRui Medicine Co., Ltd. 692
Large-scale testing (Phase 3)Study completedNCT02666664
What this trial is testing

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Diseases
Esperion Therapeutics, Inc. 2,230
Large-scale testing (Phase 3)Not Yet RecruitingNCT07444086
What this trial is testing

QLC7401 Monotherapy in Non-familial Hypercholesterolemia or Mixed Dyslipidemia

Who this might be right for
Primary Hypercholesterolemia or Mixed Hyperlipidemia
Qilu Pharmaceutical Co., Ltd. 510
Large-scale testing (Phase 3)Study completedNCT02991118
What this trial is testing

Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Disease
Esperion Therapeutics, Inc. 779
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