Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Non-familial Hypercholesterolemia”

20 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 20 results

Large-scale testing (Phase 3)Study completedNCT01623115
What this trial is testing

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Who this might be right for
Hypercholesterolemia
Sanofi 486
Not applicableLooking for participantsNCT06331195
What this trial is testing

An Adapted Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Familial Hypercholesterolemia (DICA-FH)

Who this might be right for
Familial Hypercholesterolemia
Hospital do Coracao 300
Large-scale testing (Phase 3)Study completedNCT04885218
What this trial is testing

Efficacy and Safety of SHR-1209 Combined With Lipid-lowering Agents in Patients With Hypercholesterolemia

Who this might be right for
Non-familial HypercholesterolemiaMixed Hyperlipidemia
Jiangsu HengRui Medicine Co., Ltd. 692
Large-scale testing (Phase 3)Study completedNCT02666664
What this trial is testing

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Diseases
Esperion Therapeutics, Inc. 2,230
Large-scale testing (Phase 3)Study completedNCT05142722
What this trial is testing

Randomized Study to Evaluate the Effect of Obicetrapib on Top of Maximum Tolerated Lipid-Modifying Therapies

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia+2 more
NewAmsterdam Pharma 2,530
Not applicableEnded earlyNCT02345421
What this trial is testing

Identify and Characterize LAL-D Patients in High-risk Populations

Who this might be right for
Lysosomal Acid Lipase Deficiency
Alexion Pharmaceuticals, Inc. 640
Not applicableUnknownNCT05218005
What this trial is testing

Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia

Who this might be right for
Familial HypercholesterolemiaFamilial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein BFamilial Hypercholesterolemia Due to Heterozygous LDL Receptor Mutation+5 more
University of British Columbia 250
Not applicableLooking for participantsNCT06546137
What this trial is testing

National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry

Who this might be right for
Cardiomyopathy, HypertrophicCardiomyopathy, DilatedCardiomyopathy Restrictive+11 more
Hospital do Coracao 600
Large-scale testing (Phase 3)Study completedNCT02991118
What this trial is testing

Evaluation of Long-Term Efficacy of Bempedoic Acid (ETC-1002) in Patients With Hyperlipidemia at High Cardiovascular Risk

Who this might be right for
HypercholesterolemiaAtherosclerotic Cardiovascular Disease
Esperion Therapeutics, Inc. 779
Not applicableStudy completedNCT01753232
What this trial is testing

Safety and Efficacy of the DALI LDL-adsorber and MONET Lipoprotein Filter

Who this might be right for
Hypercholesterolemia, FamilialLIPOPROTEIN TYPES--Lp SYSTEM Lp(a) HYPERLIPOPROTEINEMIA
Fresenius Medical Care Deutschland GmbH 108
Large-scale testing (Phase 3)Study completedNCT02107898
What this trial is testing

Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)

Who this might be right for
Hypercholesterolemia
Sanofi 216
Not applicableLooking for participantsNCT07086989
What this trial is testing

Cardiovascular Risk in Children With Chronic Conditions Study

Who this might be right for
Kidney TransplantFamilial HypercholesterolaemiaType 1 Diabetes Mellitus (T1DM)+22 more
Semmelweis University 300
Post-approval studies (Phase 4)Ended earlyNCT03694197
What this trial is testing

Long Term Safety Study of PRALUENT

Who this might be right for
Heterozygous Familial HypercholesterolemiaNon-familial Hypercholesterolemia
Regeneron Pharmaceuticals 1,389
Large-scale testing (Phase 3)Study completedNCT00654602
What this trial is testing

48-wk Open Label Phase IIIb to Evaluate Efficacy and Safety

Who this might be right for
Dyslipidaemia
AstraZeneca 1,500
Large-scale testing (Phase 3)Study completedNCT04289285
What this trial is testing

Safety and Efficacy of IBI306 in Chinese Subjects With Non-familial Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 804
Large-scale testing (Phase 3)Study completedNCT01709500
What this trial is testing

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Regeneron Pharmaceuticals 249
Not applicableStudy completedNCT04261803
What this trial is testing

FH Detection in Children by Salivary Test

Who this might be right for
Hyperlipoproteinemia Type II
Hospices Civils de Lyon 60
Large-scale testing (Phase 3)Study completedNCT05425745
What this trial is testing

Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies.

Who this might be right for
DyslipidemiasHigh CholesterolHypercholesterolemia+6 more
NewAmsterdam Pharma 354
Not applicableNot Yet RecruitingNCT06675994
What this trial is testing

In Vitro Demonstration of Direct Platelet-Related Effects of PCSK9 Enzyme

Who this might be right for
HealthyHypercholesterolemiaHypertension+6 more
LifeBridge Health 80
Post-approval studies (Phase 4)Study completedNCT02957682
What this trial is testing

Evaluating Effect of the Study Drug Praluent (Alirocumab) on Neurocognitive Function When Compared to Placebo

Who this might be right for
Hypercholesterolemia
Regeneron Pharmaceuticals 2,176