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Results for “Noonan Syndrome”

52 trials

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Showing 20 of 52 results

Not applicableLooking for participantsNCT06147414
What this trial is testing

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

Who this might be right for
Invasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, IncludingSickle Cell DiseaseCystic Fibrosis+12 more
Assistance Publique - Hôpitaux de Paris 550
Not applicableStudy completedNCT02383316
What this trial is testing

Study of Metabolic Modifications in Children With Noonan Syndrome

Who this might be right for
Child Syndrome
University Hospital, Toulouse 20
Early research (Phase 1)Study completedNCT04959981
What this trial is testing

Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Advanced NSCLC

Who this might be right for
Advanced Non-squamous Non-small-cell Lung Cancer
Erasca, Inc. 24
Early research (Phase 1)Study completedNCT04252339
What this trial is testing

RLY-1971 in Subjects With Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumor, Unspecified, Adult
Hoffmann-La Roche 56
Not applicableLooking for participantsNCT03050268
What this trial is testing

Familial Investigations of Childhood Cancer Predisposition

Who this might be right for
Acute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more
St. Jude Children's Research Hospital 1,500
Not applicableLooking for participantsNCT04395495
What this trial is testing

RASopathy Biorepository

Who this might be right for
RAS MutationNeurofibromatosis 1Noonan Syndrome+11 more
Children's Hospital Medical Center, Cincinnati 1,000
Testing effectiveness (Phase 2)Looking for participantsNCT06668805
What this trial is testing

A Basket Study of Vosoritide in Children With Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

Who this might be right for
Short Stature Homeobox- Containing Gene SHOX DeficiencyNoonan SyndromeTurner Syndrome
BioMarin Pharmaceutical 54
Not applicableLooking for participantsNCT07336394
What this trial is testing

Precision Diagnosis and Risk Stratification of Rare Cardiomyopathies Based on Novel Cardiac Magnetic Resonance Techniques

Who this might be right for
Danon DiseaseFabry DiseaseCardiac Amyloidosis+4 more
Chinese Academy of Medical Sciences, Fuwai Hospital 1,000
Not applicableStudy completedNCT02486731
What this trial is testing

Hormonal Sensitivity in Patients With Noonan and LEOPARD Syndromes

Who this might be right for
Noonan SyndromeLEOPARD Syndrome
Institut National de la Santé Et de la Recherche Médicale, France 27
Early research (Phase 1)Study completedNCT03518554
What this trial is testing

A First in Human, Dose Escalation Study of JAB-3068 （SHP2 Inhibitor） in Adult Patients With Advanced Solid Tumors

Who this might be right for
Non-small Cell Lung CancerHead and Neck CancerEsophageal Cancer+1 more
Jacobio Pharmaceuticals Co., Ltd. 38
Not applicableLooking for participantsNCT05761314
What this trial is testing

Solid Tumors in RASopathies

Who this might be right for
RASopathyCostello SyndromeCardio-Facio-Cutaneous Syndrome+1 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 100
Not applicableLooking for participantsNCT06331117
What this trial is testing

Effect of RAS/MAPK Pathway Hyperactivation on Growth' and Bone' Profile of the RASopathies

Who this might be right for
RASopathyCostello SyndromeNoonan Syndrome+1 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 120
Not applicableNot Yet RecruitingNCT07259135
What this trial is testing

Link Between Abnormal Bleeding and Coagulation Disorders in Noonan Syndromes

Who this might be right for
Noonan Syndrome
University Hospital, Bordeaux 100
Testing effectiveness (Phase 2)Looking for participantsNCT06555237
What this trial is testing

MEK Inhibitors for the Treatment of Hypertrophic Cardiomyopathy in Patients With RASopathies

Who this might be right for
CardiomegalyNoonan Syndrome
Medical University of Warsaw 40
Not applicableLooking for participantsNCT07464821
What this trial is testing

National Multicentre Study on Lipid Profile in Noonan Syndrome and Related Disorders: Trends by Age, Gender and Genotype

Who this might be right for
RASopathiesNoonan Syndrome
IRCCS Azienda Ospedaliero-Universitaria di Bologna 200
Large-scale testing (Phase 3)Active Not RecruitingNCT05723835
What this trial is testing

A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9

Who this might be right for
SGATurner SyndromeNoonan Syndrome+1 more
Novo Nordisk A/S 47
Not applicableStudy completedNCT06267807
What this trial is testing

Lymphatic Phenotype in Noonan Syndrome Spectrum Disorders

Who this might be right for
Lymphatic System Disorders CongenitalLymphatic DiseasesNoonan Syndrome+1 more
Radboud University Medical Center 9
Testing effectiveness (Phase 2)UnknownNCT05715398
What this trial is testing

BR790 in Combination With Anlotinib in Adult Subjects With Advanced Non-Small Cell Lung Cancer

Who this might be right for
Non-Small Cell Lung Cancer
Shanghai Gopherwood Biotech Co., Ltd. 90
Large-scale testing (Phase 3)Study completedNCT00452725
What this trial is testing

Effect of MAXOMAT ® on the Growth of Small Children to NOONAN's Syndrome

Who this might be right for
Noonan Syndrome
Sanofi 36
Not applicableLooking for participantsNCT05202210
What this trial is testing

Constitution of a Biological Collection to Study the Pathophysiology in Noonan Syndrome

Who this might be right for
Noonan Syndrome
University Hospital, Toulouse 100
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