Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Noonan syndrome”

53 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 53 results

Not applicableUnknownNCT06355622
What this trial is testing

Prevalence and Characterization of Pain in RASopathies

Who this might be right for
RASopathyCostello SyndromeCardio-Facio-Cutaneous Syndrome+1 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 150
Not applicableUnknownNCT06455956
What this trial is testing

Use of miRNAs in Growth Hormone Deficiency (GHD)

Who this might be right for
Growth Hormone Deficiency
University of Parma 400
Testing effectiveness (Phase 2)WithdrawnNCT01556568
What this trial is testing

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MEK162 in Noonan Syndrome Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomegaly
Array Biopharma, now a wholly owned subsidiary of Pfizer
Large-scale testing (Phase 3)Active Not RecruitingNCT05330325
What this trial is testing

A Research Study to Compare Somapacitan Once a Week With Norditropin® Once a Day in Children Who Need Help to Grow

Who this might be right for
SGA, Turner Syndrome, Noonan Syndrome, ISS
Novo Nordisk A/S 412
Not applicableStudy completedNCT02486731
What this trial is testing

Hormonal Sensitivity in Patients With Noonan and LEOPARD Syndromes

Who this might be right for
Noonan SyndromeLEOPARD Syndrome
Institut National de la Santé Et de la Recherche Médicale, France 27
Not applicableLooking for participantsNCT07336394
What this trial is testing

Precision Diagnosis and Risk Stratification of Rare Cardiomyopathies Based on Novel Cardiac Magnetic Resonance Techniques

Who this might be right for
Danon DiseaseFabry DiseaseCardiac Amyloidosis+4 more
Chinese Academy of Medical Sciences, Fuwai Hospital 1,000
Not applicableUnknownNCT06331117
What this trial is testing

Effect of RAS/MAPK Pathway Hyperactivation on Growth' and Bone' Profile of the RASopathies

Who this might be right for
RASopathyCostello SyndromeNoonan Syndrome+1 more
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 120
Large-scale testing (Phase 3)Active Not RecruitingNCT05566795
What this trial is testing

DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)

Who this might be right for
Low-grade GliomaRapidly Accelerated Fibrosarcoma (RAF) Altered GliomaPediatric Low-grade Glioma
Day One Biopharmaceuticals, Inc. 418
Not applicableStudy completedNCT06267807
What this trial is testing

Lymphatic Phenotype in Noonan Syndrome Spectrum Disorders

Who this might be right for
Lymphatic System Disorders CongenitalLymphatic DiseasesNoonan Syndrome+1 more
Radboud University Medical Center 9
Large-scale testing (Phase 3)Study completedNCT02713945
What this trial is testing

Treatment With HMG-COA Reductase Inhibitor of Growth and Bone Abnormalities in Children With Noonan Syndrome

Who this might be right for
Noonan Syndrome
University Hospital, Toulouse 53
Testing effectiveness (Phase 2)Ended earlyNCT03504501
What this trial is testing

Synaptic Plasticity and Cognitive Function in RASopathies

Who this might be right for
Impaired Synaptic PlasticityImpaired Cognition
Technical University of Munich 16
Not applicableLooking for participantsNCT04395495
What this trial is testing

RASopathy Biorepository

Who this might be right for
RAS MutationNeurofibromatosis 1Noonan Syndrome+11 more
Children's Hospital Medical Center, Cincinnati 1,000
Early research (Phase 1)Study completedNCT04959981
What this trial is testing

Anti-Cancer Therapies Targeting the MAPK Pathway in Patients With Advanced NSCLC

Who this might be right for
Advanced Non-squamous Non-small-cell Lung Cancer
Erasca, Inc. 24
Early research (Phase 1)Study completedNCT01787500
What this trial is testing

Vemurafenib, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or That Cannot Be Removed by Surgery

Who this might be right for
BRAF NP_004324.2:p.V600XKRAS wt AlleleMetastatic Malignant Solid Neoplasm+4 more
M.D. Anderson Cancer Center 47
Early research (Phase 1)Study completedNCT03518554
What this trial is testing

A First in Human, Dose Escalation Study of JAB-3068 （SHP2 Inhibitor） in Adult Patients With Advanced Solid Tumors

Who this might be right for
Non-small Cell Lung CancerHead and Neck CancerEsophageal Cancer+1 more
Jacobio Pharmaceuticals Co., Ltd. 38
Large-scale testing (Phase 3)Study completedNCT01927861
What this trial is testing

Investigating the Long-term Efficacy and Safety of Two Doses of NN-220 (Somatropin) in Short Stature Due to Noonan Syndrome

Who this might be right for
Genetic DisorderNoonan Syndrome
Novo Nordisk A/S 51
Not applicableLooking for participantsNCT04888936
What this trial is testing

Clinical, Genetic, and Epidemiologic Study of Children and Adults With RASopathies

Who this might be right for
Costello SyndromeNoonan SyndromeCardiofaciocutaneous Syndrome+3 more
National Cancer Institute (NCI) 500
Not applicableStudy completedNCT00960128
What this trial is testing

Observational Prospective Study on Patients Treated With Norditropin®

Who this might be right for
Growth Hormone DisorderGrowth Hormone Deficiency in ChildrenAdult Growth Hormone Deficiency+7 more
Novo Nordisk A/S 21,249
Not applicableStudy completedNCT06550635
What this trial is testing

Joint and Hematologic Disorders of Noonan Syndrome: French Descriptive Cross-sectional Study

Who this might be right for
Noonan Syndrome
University Hospital, Brest 71
Early research (Phase 1)Study completedNCT04121286
What this trial is testing

JAB-3312 in Adult Patients With Advanced Solid Tumors in China

Who this might be right for
Non-small Cell Lung CancerColorectal CancerPancreatic Ductal Carcinoma+4 more
Allist Pharmaceuticals, Inc. 17
Next Page