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Results for “Noonan syndrome”

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Showing 13 of 0 results

Large-scale testing (Phase 3)Active Not RecruitingNCT05723835
What this trial is testing

A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9

Who this might be right for
SGATurner SyndromeNoonan Syndrome+1 more
Novo Nordisk A/S 47
Large-scale testing (Phase 3)Not Yet RecruitingNCT07817186
What this trial is testing

Clinical Trial of a MEK Inhibitor for RASopathy-Associated Severe Infantile Hypertrophic Cardiomyopathy: Baby MERIT

Who this might be right for
HCMNoonan Syndrome and Other RasopathyHeart Failure (Pediatric)
Carelon Research 25
Early research (Phase 1)UnknownNCT03634982
What this trial is testing

Dose Escalation of RMC-4630 Monotherapy in Relapsed/Refractory Solid Tumors

Who this might be right for
Solid Tumors
Revolution Medicines, Inc. 133
Testing effectiveness (Phase 2)Looking for participantsNCT06668805
What this trial is testing

Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

Who this might be right for
Noonan Syndrome
BioMarin Pharmaceutical 30
Not applicableLooking for participantsNCT07464821
What this trial is testing

National Multicentre Study on Lipid Profile in Noonan Syndrome and Related Disorders: Trends by Age, Gender and Genotype

Who this might be right for
RASopathiesNoonan Syndrome
IRCCS Azienda Ospedaliero-Universitaria di Bologna 200
Not applicableEnrolling By InvitationNCT06938542
What this trial is testing

Palliative Care Needs of Children With Rare Diseases and Their Families

Who this might be right for
Trisomy 13 SyndromeArthrogryposis Congenita Multiplex With Intestinal AtresiaAsparagine Synthetase Deficiency+16 more
Children's National Research Institute 480
Testing effectiveness (Phase 2)Study completedNCT01885195
What this trial is testing

MEK162 for Patients With RAS/RAF/MEK Activated Tumors

Who this might be right for
Solid Tumor and Hematologic Malignancies
Pfizer 110
Not applicableLooking for participantsNCT03050268
What this trial is testing

Familial Investigations of Childhood Cancer Predisposition

Who this might be right for
Acute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more
St. Jude Children's Research Hospital 1,500
Not applicableLooking for participantsNCT04463316
What this trial is testing

GROWing Up With Rare GENEtic Syndromes

Who this might be right for
Prader-Willi SyndromePWS-like SyndromeSilver Russel Syndrome+30 more
dr. Laura C. G. de Graaff-Herder 600
Early research (Phase 1)Ended earlyNCT03114319
What this trial is testing

Dose Finding Study of TNO155 in Adult Patients With Advanced Solid Tumors

Who this might be right for
Advanced EGFR Mutant Non Small Cell LungCancer (NSCLC)KRAS G12-mutant NSCLCEsophageal Squamous Cell Cancer (SCC)+4 more
Novartis Pharmaceuticals 227
Not applicableStudy completedNCT02383316
What this trial is testing

Study of Metabolic Modifications in Children With Noonan Syndrome

Who this might be right for
Child Syndrome
University Hospital, Toulouse 20
Not applicableLooking for participantsNCT06147414
What this trial is testing

Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders

Who this might be right for
Invasive PreNatal Diagnosis in a Context of Family History of Single-gene Disorders, IncludingSickle Cell DiseaseCystic Fibrosis+12 more
Assistance Publique - Hôpitaux de Paris 550
Not applicableLooking for participantsNCT05202210
What this trial is testing

Constitution of a Biological Collection to Study the Pathophysiology in Noonan Syndrome

Who this might be right for
Noonan Syndrome
University Hospital, Toulouse 100