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Results for “Novel Mutation”

67 trials

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Showing 20 of 67 results

Testing effectiveness (Phase 2)Study completedNCT00126880
What this trial is testing

AVX754 (a New Nucleoside Reverse Transcriptase Inhibitor [NRTI]) to Treat Drug-resistant HIV

Who this might be right for
HIV Infections
Avexa 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07750574
What this trial is testing

Flonoltinib Maleate Oral Regimens in Patients With Myelofibrosis

Who this might be right for
MyelofibrosisMyelofibrosis Due to and Following Polycythemia VeraMyelofibrosis Transformation in Essential Thrombocythemia+9 more
Chengdu Zenitar Biomedical Technology Co., Ltd 105
Testing effectiveness (Phase 2)Study completedNCT00260000
What this trial is testing

Study of BH4, a New and Simple Treatment of Mild PKU

Who this might be right for
Phenylketonuria
The Kennedy Institute-National Eye Clinic 15
Early research (Phase 1)UnknownNCT03827070
What this trial is testing

Dry Pleurodesis With Talcum and Afatinib is Used to Treat Patients With Non-Small Cell Lung Carcinoma

Who this might be right for
Non Small Cell Lung Cancer
Center Trials & Treatment Europe 12
Not applicableActive Not RecruitingNCT05692596
What this trial is testing

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

Who this might be right for
Pancreatic Ductal AdenocarcinomaPancreatic CystChronic Pancreatitis+10 more
H. Lee Moffitt Cancer Center and Research Institute 317
Not applicableActive Not RecruitingNCT03246841
What this trial is testing

Investigation of Tumour Spectrum of Germline Mutations in Breast and Ovarian Cancer Genes.

Who this might be right for
Hereditary Breast and Ovarian CancerMutation
UNICANCER 7,274
Not applicableStudy completedNCT02194881
What this trial is testing

Ivacaftor in French Patients With Cystic Fibrosis and a G551D Mutation

Who this might be right for
Cystic Fibrosis
Assistance Publique - Hôpitaux de Paris 57
Post-approval studies (Phase 4)Active Not RecruitingNCT05457257
What this trial is testing

Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
AstraZeneca 43
Testing effectiveness (Phase 2)UnknownNCT04843839
What this trial is testing

CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops

Who this might be right for
Congenital Hereditary Endothelial Dystrophy of Cornea
L.V. Prasad Eye Institute 30
Testing effectiveness (Phase 2)Looking for participantsNCT07007949
What this trial is testing

A New Treatment of Newly Diagnosed IDH1 Mutation Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaIDH1 Gene MutationIvosidenib
The First Affiliated Hospital of Soochow University 42
Not applicableStudy completedNCT04068961
What this trial is testing

New Strategies of Genetic Study of Patients With Oculocutaneous Albinism

Who this might be right for
Oculocutaneous AlbinismMutation
University Hospital, Bordeaux 64
Post-approval studies (Phase 4)Ended earlyNCT03624101
What this trial is testing

Novel Therapeutic Approaches for Treatment of CF Patients With W1282X Premature Termination Codon Mutations

Who this might be right for
Cystic Fibrosis
University of Alabama at Birmingham 1
Early research (Phase 1)Study completedNCT03900949
What this trial is testing

Gentuzumab Ozogamicin and Midostaurin Combination With Standard Cytarabine and Danunorubi Midostaurin as a Novel Approach to Treating Patients With Newly Diagnosed FLT-3 Mutated Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
Uma Borate 21
Not applicableLooking for participantsNCT06762379
What this trial is testing

Implementation of a New Algorithm for HRR Gene Mutation Testing in Patients With mPC Through Liquid Biopsy Integration

Who this might be right for
Metastatic Prostate Cancer (mPC)
European Institute of Oncology 125
Not applicableLooking for participantsNCT07315542
What this trial is testing

Diagnostic and Therapeutic Targets in Cartilaginous Tumours

Who this might be right for
ChondrosarcomasCartilage Tumours
St. Anne's University Hospital Brno, Czech Republic 300
Not applicableUnknownNCT02666755
What this trial is testing

Novel Detection System for Lung Cancer Curative Effect Monitoring

Who this might be right for
Lung Neoplasms
Jian Zhang 160
Very early researchStudy completedNCT04901715
What this trial is testing

Functional Studies of Novel Genes Mutated in Primary Ciliary Dyskinesia II: Genotype to Phenotype

Who this might be right for
Primary Ciliary Dyskinesia
University of North Carolina, Chapel Hill 27
Not applicableUnknownNCT02284633
What this trial is testing

Blood Sample Monitoring of Patients With EGFR Mutated Lung Cancer

Who this might be right for
Lung Neoplasms
Aarhus University Hospital 250
Testing effectiveness (Phase 2)Looking for participantsNCT06976658
What this trial is testing

Glucokinase Activator in Monogenic Diabetes

Who this might be right for
Diabetes MellitusMonogenic Diabetes
Chinese University of Hong Kong 44
Not applicableActive Not RecruitingNCT06863818
What this trial is testing

Overcoming Resistance to EGFR Neutralization by Combination of Monoclonal Antibodies and Novel Cancer Drugs

Who this might be right for
Non Small Cell Lung Cancer
IRCCS Azienda Ospedaliero-Universitaria di Bologna 30
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