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Results for “Novel Mutation”

66 trials

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Showing 20 of 66 results

Testing effectiveness (Phase 2)Study completedNCT00126880
What this trial is testing

AVX754 (a New Nucleoside Reverse Transcriptase Inhibitor [NRTI]) to Treat Drug-resistant HIV

Who this might be right for
HIV Infections
Avexa 52
Not applicableActive Not RecruitingNCT03246841
What this trial is testing

Investigation of Tumour Spectrum of Germline Mutations in Breast and Ovarian Cancer Genes.

Who this might be right for
Hereditary Breast and Ovarian CancerMutation
UNICANCER 7,274
Early research (Phase 1)UnknownNCT03827070
What this trial is testing

Dry Pleurodesis With Talcum and Afatinib is Used to Treat Patients With Non-Small Cell Lung Carcinoma

Who this might be right for
Non Small Cell Lung Cancer
Center Trials & Treatment Europe 12
Testing effectiveness (Phase 2)Looking for participantsNCT06976658
What this trial is testing

Glucokinase Activator in Monogenic Diabetes

Who this might be right for
Diabetes MellitusMonogenic Diabetes
Chinese University of Hong Kong 44
Testing effectiveness (Phase 2)Looking for participantsNCT07007949
What this trial is testing

A New Treatment of Newly Diagnosed IDH1 Mutation Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid LeukemiaIDH1 Gene MutationIvosidenib
The First Affiliated Hospital of Soochow University 42
Large-scale testing (Phase 3)Ended earlyNCT02697136
What this trial is testing

CER-001 Therapy as a Novel Approach to Treat Genetic Orphan Diseases

Who this might be right for
Familial Hypoalphalipoproteinemia
Cerenis Therapeutics, SA 30
Not applicableEnded earlyNCT04658251
What this trial is testing

Study of New Mutations in Cone Disorders

Who this might be right for
Retinal Dystrophy, Cone-RodCone DystrophyCone Rod Dystrophy+1 more
University Hospital, Lille 7
Not applicableActive Not RecruitingNCT05692596
What this trial is testing

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

Who this might be right for
Pancreatic Ductal AdenocarcinomaPancreatic CystChronic Pancreatitis+10 more
H. Lee Moffitt Cancer Center and Research Institute 317
Testing effectiveness (Phase 2)Study completedNCT00260000
What this trial is testing

Study of BH4, a New and Simple Treatment of Mild PKU

Who this might be right for
Phenylketonuria
The Kennedy Institute-National Eye Clinic 15
Testing effectiveness (Phase 2)UnknownNCT05767866
What this trial is testing

Assessing an Oral EGFR Inhibitor,YK-209A in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR

Who this might be right for
TreatmentTreatment Side Effects
Suzhou Puhe Pharmaceutical Technology Co., LTD 160
Large-scale testing (Phase 3)Ended earlyNCT00612898
What this trial is testing

Study of the Efficacy and Safety of Apricitabine, a New NRTI, to Treat Drug-resistant HIV Infection

Who this might be right for
HIV Infections
Avexa 239
Not applicableStudy completedNCT02841085
What this trial is testing

New Genetic Mutations in Thromboembolic Venous Disease Idiopathic. Study "FIT GENETIQUE".

Who this might be right for
Thromboembolic Venous Disease
University Hospital, Brest 613
Early research (Phase 1)Study completedNCT03900949
What this trial is testing

Gentuzumab Ozogamicin and Midostaurin Combination With Standard Cytarabine and Danunorubi Midostaurin as a Novel Approach to Treating Patients With Newly Diagnosed FLT-3 Mutated Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia
Uma Borate 21
Not applicableStudy completedNCT03493230
What this trial is testing

Detection of Plasmatic Cell-free BRAF and NRAS Mutations : a New Tool for Monitoring Patients With Metastatic Malignant Melanoma Treated With Targeted Therapies or Immunotherapy ( MALT )

Who this might be right for
Malignant Melanoma Stage IVMalignant Melanoma Stage III
Centre Hospitalier Universitaire de Nice 35
Testing effectiveness (Phase 2)Looking for participantsNCT06229340
What this trial is testing

Leflunomide or Combination of MEK Inhibitor and Hydroxychloroquine for Refractory Patients With RAS Mutations

Who this might be right for
RAS MutationRas (Kras or Nras) Gene MutationColorectal Cancer Recurrent+4 more
N.N. Petrov National Medical Research Center of Oncology 20
Not applicableLooking for participantsNCT06762379
What this trial is testing

Implementation of a New Algorithm for HRR Gene Mutation Testing in Patients With mPC Through Liquid Biopsy Integration

Who this might be right for
Metastatic Prostate Cancer (mPC)
European Institute of Oncology 125
Not applicableStudy completedNCT07607392
What this trial is testing

JAK2V617F Mutated Endothelium Has a Stem Cell Potential in Primary Myelofibrosis: a New Disease Ontogenesis for Chronic Myeloproliferative Disorders

Who this might be right for
Primary Myelofibrosids
Fondazione IRCCS Policlinico San Matteo di Pavia 30
Not applicableActive Not RecruitingNCT06863818
What this trial is testing

Overcoming Resistance to EGFR Neutralization by Combination of Monoclonal Antibodies and Novel Cancer Drugs

Who this might be right for
Non Small Cell Lung Cancer
IRCCS Azienda Ospedaliero-Universitaria di Bologna 30
Post-approval studies (Phase 4)Active Not RecruitingNCT05457257
What this trial is testing

Clinical Study to Assess the Efficacy and Safety of Olaparib in Chinese Patients With Metastatic Castration-Resistant Prostate Cancer Who Have Failed Prior Treatment With a New Hormonal Agent and Have BRCA1/2 Mutations

Who this might be right for
Metastatic Castration-resistant Prostate Cancer
AstraZeneca 43
Testing effectiveness (Phase 2)Ended earlyNCT04161391
What this trial is testing

Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations

Who this might be right for
Non Small Cell Lung CancerMedullary Thyroid CancerRET Gene Mutation+2 more
Turning Point Therapeutics, Inc. 41
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