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Results for “Novel Mutation”

65 trials

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Showing 20 of 65 results

Early research (Phase 1)Study completedNCT02729298
What this trial is testing

First-in-human Study of Oral TP-0903 (a Novel Inhibitor of AXL Kinase) in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid TumorsEGFR Positive Non-small Cell Lung CancerColorectal Carcinoma+2 more
Sumitomo Pharma America, Inc. 177
Not applicableEnrolling By InvitationNCT06730477
What this trial is testing

Plasma Exosomes Reveal the Efficacy of Targeted Therapy in Patients With EGFR Mutation in Lung Adenocarcinoma

Who this might be right for
Lung AdenocarcinomaEGFR Activating Mutation
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 500
Testing effectiveness (Phase 2)Active Not RecruitingNCT03047213
What this trial is testing

Sapanisertib in Treating Patients With Locally Advanced or Metastatic Bladder Cancer With TSC1 and/or TSC2 Mutations

Who this might be right for
Locally Advanced Bladder Urothelial CarcinomaMetastatic Transitional Cell CarcinomaMetastatic Urothelial Carcinoma+3 more
National Cancer Institute (NCI) 17
Not applicableUnknownNCT04620980
What this trial is testing

Assessing the Polygenic Burden of Rare Disruptive Mutations in Parkinson's Disease

Who this might be right for
Parkinson Disease
Neuromed IRCCS 600
Large-scale testing (Phase 3)Ended earlyNCT00612898
What this trial is testing

Study of the Efficacy and Safety of Apricitabine, a New NRTI, to Treat Drug-resistant HIV Infection

Who this might be right for
HIV Infections
Avexa 239
Not applicableLooking for participantsNCT05929365
What this trial is testing

Innovative Approach to Detect Recurrent Colorectal Lesions With Surveillance Via Mutation Analysis & Clinical Phenotype

Who this might be right for
Predictive Cancer Model
Military University Hospital, Prague 200
Testing effectiveness (Phase 2)UnknownNCT04843839
What this trial is testing

CHED - Congenital Hereditary Endothelial Dystrophy: New Paradigm Shift in Therapy Using Topical Eye Drops

Who this might be right for
Congenital Hereditary Endothelial Dystrophy of Cornea
L.V. Prasad Eye Institute 30
Early research (Phase 1)UnknownNCT03827070
What this trial is testing

Dry Pleurodesis With Talcum and Afatinib is Used to Treat Patients With Non-Small Cell Lung Carcinoma

Who this might be right for
Non Small Cell Lung Cancer
Center Trials & Treatment Europe 12
Testing effectiveness (Phase 2)Ended earlyNCT04161391
What this trial is testing

Study of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or Mutations

Who this might be right for
Non Small Cell Lung CancerMedullary Thyroid CancerRET Gene Mutation+2 more
Turning Point Therapeutics, Inc. 41
Not applicableUnknownNCT02666755
What this trial is testing

Novel Detection System for Lung Cancer Curative Effect Monitoring

Who this might be right for
Lung Neoplasms
Jian Zhang 160
Not applicableUnknownNCT03597958
What this trial is testing

Genetic Causes of Hypercholesterolaemia in the Emirati Population

Who this might be right for
Familial Hypercholesterolemia
Imperial College London Diabetes Centre 1,000
Not applicableLooking for participantsNCT00697411
What this trial is testing

Study of Selected X-Linked Disorders: Aicardi Syndrome

Who this might be right for
Aicardi SyndromeBrain Disorders
Baylor College of Medicine 500
Testing effectiveness (Phase 2)Looking for participantsNCT07028073
What this trial is testing

A New Treatment of Newly Diagnosed KIT Mutation CBF-Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukemia With T(8;21)(Q22;Q22)Acute Myeloid Leukemia With T(16;16)(P13;Q22)KIT Gene Mutation+1 more
The First Affiliated Hospital of Soochow University 78
Not applicableStudy completedNCT04068961
What this trial is testing

New Strategies of Genetic Study of Patients With Oculocutaneous Albinism

Who this might be right for
Oculocutaneous AlbinismMutation
University Hospital, Bordeaux 64
Not applicableActive Not RecruitingNCT03246841
What this trial is testing

Investigation of Tumour Spectrum of Germline Mutations in Breast and Ovarian Cancer Genes.

Who this might be right for
Hereditary Breast and Ovarian CancerMutation
UNICANCER 7,274
Not applicableLooking for participantsNCT07085533
What this trial is testing

Natural History Study of Inherited Retinal Diseases

Who this might be right for
Retinal DystrophiesColor Vision DefectsVision Disorders+7 more
Zhongmou Therapeutics 200
Testing effectiveness (Phase 2)Study completedNCT00126880
What this trial is testing

AVX754 (a New Nucleoside Reverse Transcriptase Inhibitor [NRTI]) to Treat Drug-resistant HIV

Who this might be right for
HIV Infections
Avexa 52
Early research (Phase 1)Study completedNCT06001671
What this trial is testing

Antitumor Activity and Safety of BEBT-109, a Novel EGFR Inhibitor, in Previously Treated NSCLC

Who this might be right for
NSCLC
Hunan Province Tumor Hospital 23
Testing effectiveness (Phase 2)UnknownNCT05767866
What this trial is testing

Assessing an Oral EGFR Inhibitor,YK-209A in Patients Who Have Advanced Non-small Cell Lung Cancer With EGFR

Who this might be right for
TreatmentTreatment Side Effects
Suzhou Puhe Pharmaceutical Technology Co., LTD 160
Not applicableUnknownNCT02284633
What this trial is testing

Blood Sample Monitoring of Patients With EGFR Mutated Lung Cancer

Who this might be right for
Lung Neoplasms
Aarhus University Hospital 250
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