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Results for “OCT1”

23 trials

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Active, Not Recruiting
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Enrolling by Invitation

Showing 20 of 23 results

Post-approval studies (Phase 4)Looking for participantsNCT06056583
What this trial is testing

Drug Excretion in Breast Milk

Who this might be right for
PostpartumLactationDrugs in Breast Milk+3 more
University of Washington 50
Not applicableStudy completedNCT05463003
What this trial is testing

Impact of OCT1 and CYP2D6 Genotypes on Pharmacokinetics of Berberine in Healthy Volunteers

Who this might be right for
Pharmacokinetic Study in Healthy Volunteers
University Medicine Greifswald 42
Not applicableStudy completedNCT00947830
What this trial is testing

Investigating Intracellular and Plasma Imatinib Levels in Chronic Myeloid Leukemia

Who this might be right for
Chronic Myeloid Leukemia
Brian Leber 81
Post-approval studies (Phase 4)Study completedNCT01400191
What this trial is testing

The Inhibitory Effect of Metformin on Gluconeogenesis in Relation to Polymorphisms in Organic Cation Transporter 1

Who this might be right for
Pharmacogenetics of Metformin
University of Southern Denmark 37
Post-approval studies (Phase 4)Study completedNCT02586636
What this trial is testing

Impact of OCT1 on Metformin Tolerance

Who this might be right for
Tolerance
NHS Tayside 61
Post-approval studies (Phase 4)Study completedNCT00187681
What this trial is testing

Organic Cation Transporter 1 (OCT1), on Response to Metformin in Healthy Subjects

Who this might be right for
Other Conditions That May Be A Focus of Clinical Attention
University of California, San Francisco 20
Not applicableEnrolling By InvitationNCT06122701
What this trial is testing

Dose-dependent Kinetics of Thiamin in Healthy Volunteers With and Without Functional OCT1 Hepatic Transporters

Who this might be right for
Healthy
University Medicine Greifswald 36
Not applicableStudy completedNCT02045823
What this trial is testing

OCT Agreement and Precision Study

Who this might be right for
Normal EyesEyes With GlaucomaEyes With Retinal Disease
Topcon Medical Systems, Inc. 66
Early research (Phase 1)Study completedNCT03335423
What this trial is testing

Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug Interactions

Who this might be right for
MetforminOrganic Cation Transporter 1Codeine
University of Southern Denmark 228
Post-approval studies (Phase 4)Study completedNCT02743260
What this trial is testing

Drug Transporter Interaction Study PHENTRA_2015_KPUK

Who this might be right for
Healthy
University of Cologne 24
Post-approval studies (Phase 4)Active Not RecruitingNCT05680805
What this trial is testing

Metabolic Responses of Metformin and Genetic Polymorphisms of SLC22A1 Gene in PCOS

Who this might be right for
Polycystic Ovary SyndromeMetformin
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh 100
Early research (Phase 1)Study completedNCT02054299
What this trial is testing

Open Label Pharmacokinetic-Pharmacogenetic Study on Polymorphisms in the Organic Cation Transporter OCT1

Who this might be right for
Drug MetabolismMembrane Transport
University Medical Center Goettingen 48
Not applicableStudy completedNCT02447133
What this trial is testing

TopQ Cut-off Score Validation Study for 3D OCT-1 Maestro

Who this might be right for
Subjects Presenting With Normal Eyes
Topcon Medical Systems, Inc. 12
Not applicableStudy completedNCT01986478
What this trial is testing

OCT Reference Database

Who this might be right for
Healthy
Topcon Medical Systems, Inc. 389
Early research (Phase 1)Study completedNCT03011463
What this trial is testing

Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

Who this might be right for
PharmacokineticsInhibition EnzymeDrug Interaction Potentiation
Dr. R. Pfleger Chemische Fabrik GmbH 24
Post-approval studies (Phase 4)WithdrawnNCT00588172
What this trial is testing

Genetic Variation in OCT1 and Response to Metformin

Who this might be right for
Type 2 Diabetes
Mayo Clinic
Not applicableStudy completedNCT02203981
What this trial is testing

TopQ Cut-off Determination Study For 3D-OCT 1 Maestro and 3D OCT-2000

Who this might be right for
Healthy
Topcon Medical Systems, Inc. 12
Not applicableStudy completedNCT02447120
What this trial is testing

Topcon 3D OCT-1 Maestro Reference Database Study II

Who this might be right for
Healthy
Topcon Medical Systems, Inc. 504
Not applicableStudy completedNCT01809704
What this trial is testing

Clinical Validation of New OCT System

Who this might be right for
Subjects Presenting With Normal or With Ocular Pathology
Topcon Medical Systems, Inc. 87
Early research (Phase 1)Study completedNCT04086719
What this trial is testing

An Investigational Study to Determine the Drug Level Profile of BMS-986165 in Healthy Male Volunteers Following Transporter Inhibition.

Who this might be right for
Healthy Male Volunteers
Bristol-Myers Squibb 16
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