Early research (Phase 1)Study completedNCT07543276What this trial is testingPharmacokinetic (PK) Evaluation of Nalmefene FormulationsWho this might be right forOpioid Overdose Knoa Pharma LLC 13
Not applicableUnknownNCT03933345What this trial is testingOverdose Risk Management and NaloxoneWho this might be right forOpioid Use National Development and Research Institutes, Inc. 600
Large-scale testing (Phase 3)Ended earlyNCT03818399What this trial is testingVirginia Opioid Overdose Treatment InitiatVEWho this might be right forOpioid Use Disorder Virginia Commonwealth University 19
Not applicableEnrolling By InvitationNCT06084221What this trial is testingFatal Overdose Review Teams - Research to Enhance Surveillance SystemsWho this might be right forSubstance-Related DisordersOpioid-Related Disorders Indiana University 400
Early research (Phase 1)Study completedNCT06005402What this trial is testingSafety, Tolerability, and Pharmacokinetics of CSX-1004Who this might be right forOpioid OverdoseOpioid Use Disorder Cessation Therapeutics, Inc. 32
Not applicableStudy completedNCT03241771What this trial is testingImpact of Direct Outreach to Expand Access to Naloxone in the Context of Standing OrdersWho this might be right forOpioid AbuseOverdoseRisk Behavior Kaiser Permanente 325
Not applicableStudy completedNCT02535494What this trial is testingRisks and Benefits of Naloxone PrescribingWho this might be right forOpioid Overdose New York State Psychiatric Institute 405
Not applicableNot Yet RecruitingNCT07631598What this trial is testingBuprenorphine Implementation at Syringe Service Programs to Reduce OverdosesWho this might be right forOpioid Use DisorderOpioid Use Disorder, SevereOpioid Use Disorder, Moderate Montefiore Medical Center 512
Not applicableStudy completedNCT02669901What this trial is testingNaloxone Auto-injector as a Universal Precaution for Patients With Opioid Use DisorderWho this might be right forOpiate Antagonist OverdoseOpioid-Related Disorders University of New Mexico 395
Early research (Phase 1)Study completedNCT05363501What this trial is testingPharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy VolunteersWho this might be right forOpioid Overdose Pocket Naloxone Corp 76
Post-approval studies (Phase 4)Study completedNCT03908437What this trial is testingRapid Initiation of Drug Treatment EngagementWho this might be right forOpioid-use DisorderOverdose University of Pennsylvania 104
Not applicableActive Not RecruitingNCT05343169What this trial is testingCommunity-based Education, Navigation, and Support Intervention for Military VeteransWho this might be right forOverdoseOpioid Use DisorderHIV Infections New York University 300
Post-approval studies (Phase 4)WithdrawnNCT05876572What this trial is testingBlood Naloxone Levels Following Intradermal Injection in HumansWho this might be right forOpioid Overdose Johns Hopkins University
Early research (Phase 1)Study completedNCT04713709What this trial is testingA Single-Dose, Bioequivalence Study of FMXIN001 4 mg Microspheres PowderWho this might be right forOpioid Overdose Nasus Pharma 46
Post-approval studies (Phase 4)Looking for participantsNCT04811014What this trial is testingYoung Houston Emergency Opioid Engagement SystemWho this might be right forOpioid-use DisorderOpioid DependenceOpioid Overdose+2 more The University of Texas Health Science Center, Houston 250
Not applicableStudy completedNCT03821649What this trial is testingSOONER Feasibility Study ProtocolWho this might be right forOverdose Unity Health Toronto 90
Not applicableEnrolling By InvitationNCT06523985What this trial is testingThe Feasibility of Using the PulsePoint to Facilitate Overdose Education and Naloxone DistributionWho this might be right forCarrying Naloxone/Narcan on Their Person or in Their VehicleBeing Trained to Respond to an Opioid Overdose Indiana University 5,000
Not applicableStudy completedNCT03677986What this trial is testingBuprenorphine Treatment Engagement and Overdose PreventionWho this might be right forOpioid-use Disorder Johns Hopkins University 41
Not applicableUnknownNCT04815590What this trial is testingExtended-release Injectable Buprenorphine for Individuals at High Risk of OverdoseWho this might be right forOpioid-Use DisorderOpioid Overdose BC Centre on Substance Use 40
Not applicableEnded earlyNCT06303804What this trial is testingPrevention of Opioid Misuse and Overdose Deaths Among Hispanic/Latinx Adolescents: A Family-based PerspectiveWho this might be right forOpioid Misuse The University of Texas Health Science Center, Houston 6