Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Opioid Use Disorder, Severe”

39 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 39 results

Not applicableWithdrawnNCT03287180
What this trial is testing

Adolescent Community Reinforcement Approach in Combination With Buprenorphine/Naloxone for Severe Opioid Use

Who this might be right for
Opioid-Related DisordersBehavior, Addictive
Emory University
Not applicableLooking for participantsNCT07780097
What this trial is testing

TRTME: Improving Outpatient Initiation of Medication for Opioid Use Disorder Following Hospitalization

Who this might be right for
Opioid Use DisorderOpioid Use Disorder, ModerateOpioid Use Disorder, Severe
T. John Winhusen, PhD 30
Not applicableStudy completedNCT06230003
What this trial is testing

Efficacy of Erector Spinae Plane (ESP) Block in Patients With Inflammatory Bowel Disease (IBD)

Who this might be right for
Opioid Use
Samuel Lunenfeld Research Institute, Mount Sinai Hospital 67
Post-approval studies (Phase 4)UnknownNCT05594121
What this trial is testing

Monthly Versus Daily Buprenorphine Formulations for Treatment of Opiate Use Disorder

Who this might be right for
Moderate to Severe Opioid Use Disorder
Royal Victoria Hospital, Canada 90
Not applicableWithdrawnNCT03804619
What this trial is testing

Accelerated Intermittent Theta-Burst Stimulation for Opiate Use Disorder

Who this might be right for
Opiate DependenceSuicidal IdeationDepression+4 more
Stanford University
Post-approval studies (Phase 4)Study completedNCT04995029
What this trial is testing

Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in High-risk Users

Who this might be right for
Moderate to Severe Opioid-use Disorder
Indivior Inc. 785
Large-scale testing (Phase 3)Study completedNCT04556552
What this trial is testing

Non-Invasive Vagal Nerve Stimulation in Opioid Use Disorders

Who this might be right for
Substance-Related DisordersSubstance Use DisordersSubstance Abuse, Intravenous+5 more
Emory University 20
Testing effectiveness (Phase 2)UnknownNCT04850664
What this trial is testing

Computerized Chemosensory-Based Orbitofrontal Cortex (CBOT) for Opioid Use Disorder

Who this might be right for
Opioid Use Disorder, ModerateOpioid Use Disorder, SevereWithdrawal Symptoms+2 more
Evon Medics LLC 190
Not applicableStudy completedNCT05063227
What this trial is testing

Prediction of Postoperative Pain by Nociception Monitoring

Who this might be right for
Pain, PostoperativeAnalgesiaAnesthesia Recovery Period+1 more
Universitätsklinikum Hamburg-Eppendorf 60
Large-scale testing (Phase 3)Study completedNCT03661996
What this trial is testing

An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA

Who this might be right for
Knee Osteoarthritis
Centrexion Therapeutics 854
Not applicableStudy completedNCT01812733
What this trial is testing

Non-interventional Study Comparing Targiniq and Oxycodone/Laxatives

Who this might be right for
PainOpioid Induced Constipation
Mundipharma AB 37
Testing effectiveness (Phase 2)UnknownNCT03944447
What this trial is testing

Outcomes Mandate National Integration With Cannabis as Medicine

Who this might be right for
Chronic PainChronic Pain SyndromeChronic Pain Due to Injury+30 more
OMNI Medical Services, LLC 200,000
Early research (Phase 1)Ended earlyNCT06406400
What this trial is testing

Drug-Drug Interaction and Safety of AZD4041 Study (Part 1) and Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AZD4041 Study in Opioid Use Disorder (Part 2).

Who this might be right for
Opioid Use Disorder
AstraZeneca 15
Not applicableLooking for participantsNCT07734623
What this trial is testing

Applying Low-Intensity Focused Ultrasound in Treating Severe Substance Use Disorder: Tolerability and Effectiveness

Who this might be right for
Opioid Use Disorder, SevereAmphetamine Use Disorder
National Taiwan University Hospital 60
Large-scale testing (Phase 3)Study completedNCT05010148
What this trial is testing

A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain

Who this might be right for
Postoperative DeliriumPostoperative PainSpinal Fusion
University of California, San Francisco 219
Testing effectiveness (Phase 2)Study completedNCT02611752
What this trial is testing

A Multiple Dose Opioid Challenge Study

Who this might be right for
Moderate or Severe Opioid Use Disorder
Braeburn Pharmaceuticals 47
Post-approval studies (Phase 4)WithdrawnNCT04444830
What this trial is testing

Sprix for Postoperative Pain Control Following Gynecologic Surgery

Who this might be right for
Post Operative Pain ControlNarcotic UsePelvic Organ Prolapse+2 more
University of Louisville
Testing effectiveness (Phase 2)Looking for participantsNCT05529927
What this trial is testing

Efficacy and Safety of Sustained-release Dexamphetamine in Patients With Moderate to Severe Cocaine Use Disorder

Who this might be right for
Cocaine Use Disorder
Parnassia Addiction Research Centre 204
Not applicableStudy completedNCT04785456
What this trial is testing

RTMS for Suicidality in Opioid Use Disorder

Who this might be right for
Major Depressive DisorderOpioid-use Disorder
Centre for Addiction and Mental Health 10
Testing effectiveness (Phase 2)Ended earlyNCT05193318
What this trial is testing

KAP for Depression in Abstinent Opioid Users

Who this might be right for
Opioid Use Disorder, Severe, in Sustained RemissionOpioid Use Disorder, Severe, in Early RemissionMajor Depressive Disorder
Medical University of South Carolina 5
Next Page