Post-approval studies (Phase 4)UnknownNCT02934763What this trial is testingOpioid Induced Hyperalgesia (OIH) Modulation With PropranololWho this might be right forHyperalgesia Pontificia Universidad Catolica de Chile 80
Testing effectiveness (Phase 2)Study completedNCT01210079What this trial is testingHyperalgesia in Methadone-Maintained Patients: Can it be Treated?Who this might be right forOpioid-Induced Hyperalgesia University of California, Los Angeles 26
Post-approval studies (Phase 4)Study completedNCT02992938What this trial is testingAdministration of Acetazolamide to Prevent Remifentanil Induced HyperalgesiaWho this might be right forHyperalgesiaOpioid-Related Disorders University of Chile 50
Not applicableEnded earlyNCT03063905What this trial is testingThe Effects of Opioid Taper on Opioid-Induced HyperalgesiaWho this might be right forBuprenorphinePain Georgetown University 15
Post-approval studies (Phase 4)Study completedNCT03812003What this trial is testingInvestigation of the Strategy of Preventing Post-operative Opioid-induced HyperalgesiaWho this might be right forOpioid-Induced Disorders Tri-Service General Hospital (TSGH) 41
Not applicableStudy completedNCT00991809What this trial is testingStudy on the Development of Opioid Induced Hyperalgesia (OIH) After Exposure to AlfentanilWho this might be right forHyperalgesia Johns Hopkins University 22
Early research (Phase 1)UnknownNCT00333242What this trial is testingHyperalgesia in Methadone Patients: Can it be Treated?Who this might be right forOpioid-induced Hyperalgesia National Institute on Drug Abuse (NIDA) 40
Post-approval studies (Phase 4)Study completedNCT01702389What this trial is testingOpioid-induced Hyperalgesia After Remifentanil InfusionWho this might be right forHyperalgesia Oslo University Hospital 16
Not applicableStudy completedNCT02043366What this trial is testingEffect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in PatientsWho this might be right forPainAnesthesia Tianjin Medical University General Hospital 180
Testing effectiveness (Phase 2)UnknownNCT01914042What this trial is testingPrediction of Inter-individual Differences in the Response to Morphine Versus Milnacipran in Patients With SciaticaWho this might be right forNeuropathic Pain Rambam Health Care Campus 150
Early research (Phase 1)Ended earlyNCT01210066What this trial is testingPain, Opioids and Pro-Inflammatory Immune ResponsesWho this might be right forPro-inflammatory ActivityImmunologic Activity Alteration University of California, Los Angeles 21
Large-scale testing (Phase 3)Study completedNCT01301079What this trial is testingEvaluation of the Effect of Ketamine on Remifentanil-induced HyperalgesiaWho this might be right forPainHyperalgesiaInflammatory Response Federal University of São Paulo 60
Not applicableStudy completedNCT02416752What this trial is testingEffect of Remifentanil on the Recovery Profile After Prolonged Head and Neck SurgeryWho this might be right forPainHead and Neck Disorder Singapore General Hospital 222
Post-approval studies (Phase 4)Study completedNCT00246532What this trial is testingOpiate-Induced Tolerance & Hyperalgesia in Pain PatientsWho this might be right forChronic Low Back PainOpioid-induced Hyperalgesia National Institute of General Medical Sciences (NIGMS) 139
Not applicableStudy completedNCT00833755What this trial is testingEffect of Ketamine on Opioid-Induced HyperalgesiaWho this might be right forPainChronic PainHyperalgesia Massachusetts General Hospital 79
Not applicableStudy completedNCT02359006What this trial is testingThe Effects of Minocycline in Opioid-maintained PatientsWho this might be right forOpioid DependencePain Yale University 27
Not applicableStudy completedNCT02252458What this trial is testingCan Fentanyl Lead to Opioid-induced Hyperalgesia in Healthy Volunteers?Who this might be right forHealthy University Hospital, Basel, Switzerland 21
Testing effectiveness (Phase 2)Ended earlyNCT01821430What this trial is testingIncreased Sensitivity to Pain Caused by Opioids in People Who Have Abused Prescription OpioidsWho this might be right forChronic Pain Georgetown University 4
Testing effectiveness (Phase 2)WithdrawnNCT02276989What this trial is testingEvaluation of a Compliance Marker in Prescription Opioid Abusers With Chronic PainWho this might be right forComplianceChronic Pain Georgetown University
Testing effectiveness (Phase 2)Ended earlyNCT06096181What this trial is testingPropofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine SurgeryWho this might be right forAdolescent Idiopathic ScoliosisMultimodal AnalgesiaOpioid Induced Hyperalgesia+3 more Cedars-Sinai Medical Center 13