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Results for “Optic Atrophy, Hereditary, Leber”

49 trials

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Showing 20 of 49 results

Not applicableLooking for participantsNCT02435940
What this trial is testing

Inherited Retinal Degenerative Disease Registry

Who this might be right for
Eye Diseases HereditaryRetinal DiseaseAchromatopsia+25 more
Foundation Fighting Blindness 20,000
Large-scale testing (Phase 3)Study completedNCT02652767
What this trial is testing

Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation

Who this might be right for
Optic, Atrophy, Hereditary, Leber
GenSight Biologics 39
Not applicableStudy completedNCT03295071
What this trial is testing

REALITY LHON Registry

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 44
Early research (Phase 1)Not Yet RecruitingNCT07258667
What this trial is testing

Pilot Study of the Efficacy of Nicotinamide (Vitamin B3) in Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)Leber's Hereditary Optic Neuropathy (LHON)Mitochondrial Disease+1 more
University Hospital, Angers 13
Not applicableStudy completedNCT01892943
What this trial is testing

Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 306
Testing effectiveness (Phase 2)Ended earlyNCT01389817
What this trial is testing

Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Medical College of Wisconsin 4
Not applicableStudy completedNCT02796274
What this trial is testing

Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 219
Large-scale testing (Phase 3)Study completedNCT04561466
What this trial is testing

Trial of Befizal® 200 mg for the Treatment of Leber Hereditary Optic Neuropathy

Who this might be right for
Safety IssuesEfficacy, Self
Hôpital Necker-Enfants Malades 14
Large-scale testing (Phase 3)WithdrawnNCT01495715
What this trial is testing

Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals
Large-scale testing (Phase 3)Looking for participantsNCT06891443
What this trial is testing

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 32
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07303296
What this trial is testing

Efficacy and Safety Study of Bilateral IVT Injection of GS010 at Two Dose Levels in LHON Patients

Who this might be right for
Leber Hereditary Optic Disease
GenSight Biologics 14
Large-scale testing (Phase 3)Study completedNCT03406104
What this trial is testing

RESCUE and REVERSE Long-term Follow-up

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 62
Not applicableStudy completedNCT01421381
What this trial is testing

RHODOS Follow-up Single-visit Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals 60
Not applicableStudy completedNCT01267422
What this trial is testing

Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber Hereditary Optic Neuropathy
Bin Li 9
Testing effectiveness (Phase 2)Ended earlyNCT03913130
What this trial is testing

Extension Study to Study PQ-110-001 (NCT03140969)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 9
Not applicableStudy completedNCT05555784
What this trial is testing

Evaluation of Impact of Disease and Visual Disability on Quality of Life and Loss of Independence of Patients Living in France With Leber's Hereditary Optic Neuropathy (LHON) Through Qualitative and Quantitative Data Collection

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Argo Sante 12
Not applicableLooking for participantsNCT06682819
What this trial is testing

Metabolomics Analysis According to the Retinal Nerve Fiber Layer in Patients With NOHL Mutations (MétabOCT)

Who this might be right for
Healthy SubjectsLeber Hereditary Optic Neuropathy
Hôpital Necker-Enfants Malades 90
Not applicableEnrolling By InvitationNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Post-approval studies (Phase 4)Study completedNCT02774005
What this trial is testing

Study to Assess the Efficacy and Safety of Raxone in LHON Patients

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 199
Large-scale testing (Phase 3)Study completedNCT00528151
What this trial is testing

A Randomized, Double-blind, Placebo-controlled Trial of Curcumin in Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Optic Atrophy, Hereditary, Leber
Mahidol University 70
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