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Results for “Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma”

91 trials

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Showing 20 of 91 results

Testing effectiveness (Phase 2)Looking for participantsNCT06088381
What this trial is testing

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

Who this might be right for
Head and Neck CancerHead and Neck Squamous Cell CarcinomaOropharynx Cancer+2 more
University of Maryland, Baltimore 61
Testing effectiveness (Phase 2)Looking for participantsNCT05541016
What this trial is testing

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+4 more
Mayo Clinic
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06505551
What this trial is testing

Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma

Who this might be right for
HPV-Related Squamous Cell CarcinomaHPV-Related Cervical Squamous Cell CarcinomaHPV-Related Vulvar Squamous Cell Carcinoma+4 more
SCG Cell Therapy Pte. Ltd. 66
Testing effectiveness (Phase 2)Looking for participantsNCT07209189
What this trial is testing

Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)

Who this might be right for
Head and Neck CancerSquamous Cell CarcinomaOral Cavity Cancer+6 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 75
Testing effectiveness (Phase 2)Study completedNCT04180215
What this trial is testing

A Phase 1/2 Study in Patients With HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Other Cancers

Who this might be right for
HPV-Related Squamous Cell Carcinoma
Hookipa Biotech GmbH 198
Testing effectiveness (Phase 2)Looking for participantsNCT04444869
What this trial is testing

Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer

Who this might be right for
Cancer of the Head and NeckOropharynx CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
University of Missouri-Columbia 28
Large-scale testing (Phase 3)Active Not RecruitingNCT03952585
What this trial is testing

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Who this might be right for
Basaloid Squamous Cell CarcinomaClinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+5 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT03215719
What this trial is testing

Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal Carcinoma

Who this might be right for
Oropharyngeal CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
NYU Langone Health 120
Early research (Phase 1)Study completedNCT02178072
What this trial is testing

Window Trial 5-aza in HNSCC, T-tare

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Yale University 18
Testing effectiveness (Phase 2)Ended earlyNCT02225496
What this trial is testing

Robotic Surgery for Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oropharyngeal Cancer
M.D. Anderson Cancer Center 1
Not applicableStudy completedNCT03226613
What this trial is testing

New Modalities for Detection of Oropharyngeal Cancer

Who this might be right for
Human Papillomavirus Positive Oropharyngeal Squamous Cell CarcinomaOropharynx CancerBase of Tongue Carcinoma+1 more
Vanderbilt University Medical Center 51
Testing effectiveness (Phase 2)Study completedNCT04260126
What this trial is testing

Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC

Who this might be right for
Metastatic Head and Neck CancerRecurrent Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
PDS Biotechnology Corp. 95
Not applicableActive Not RecruitingNCT05814549
What this trial is testing

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

Who this might be right for
Oropharyngeal CancerHPV-Related CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Memorial Sloan Kettering Cancer Center 9
Testing effectiveness (Phase 2)Looking for participantsNCT06319963
What this trial is testing

Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal Cancer

Who this might be right for
HPV-Related Cervical CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Theravectys S.A. 72
Not applicableLooking for participantsNCT06115772
What this trial is testing

Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study

Who this might be right for
Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma
Mayo Clinic 154
Testing effectiveness (Phase 2)Active Not RecruitingNCT05232851
What this trial is testing

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Human Papillomavirus-Related CarcinomaLocally Advanced Oropharyngeal Carcinoma+2 more
Mayo Clinic 20
Testing effectiveness (Phase 2)Looking for participantsNCT05639972
What this trial is testing

E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated Cancers

Who this might be right for
HPV-Associated Cervical CarcinomaHPV-Related CarcinomaHPV-Related Malignancy+14 more
Christian Hinrichs 15
Large-scale testing (Phase 3)Active Not RecruitingNCT06790966
What this trial is testing

Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Who this might be right for
Recurrent Head and Neck CancerMetastatic Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+2 more
PDS Biotechnology Corp. 252
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06797986
What this trial is testing

A Phase I/IIa Clinical Trial to Investigate BVAC-E6E7 in Subjects with HPV Positive HNSCC.

Who this might be right for
Head and Neck Squamous Cell Carcinoma (HNSCC)HPV (human Papillomavirus)-Associated CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Cellid Co., Ltd. 37
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07418034
What this trial is testing

A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)

Who this might be right for
Head and Neck CancerHead and Neck Squamous Cell CancerHead and Neck Squamous Cell Carcinoma+11 more
University of Maryland, Baltimore 132
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