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Results for “Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma”

95 trials

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Showing 20 of 95 results

Testing effectiveness (Phase 2)Looking for participantsNCT06088381
What this trial is testing

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

Who this might be right for
Head and Neck CancerHead and Neck Squamous Cell CarcinomaOropharynx Cancer+2 more
University of Maryland, Baltimore 61
Early research (Phase 1)Study completedNCT02113878
What this trial is testing

Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

Who this might be right for
Carcinoma, Squamous Cell of Head and NeckHPV Positive Oropharyngeal Squamous Cell CarcinomaHypopharyngeal Cancer+3 more
Dana-Farber Cancer Institute 23
Not applicableLooking for participantsNCT06307015
What this trial is testing

De-escalation of Radiation Dose in HPV-associated OPC Utilising FMISO PET (DE-RADIATE)

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell Carcinoma
Royal North Shore Hospital 25
Testing effectiveness (Phase 2)Study completedNCT04260126
What this trial is testing

Study of PDS0101 and Pembrolizumab Combination I/O in Subjects With HPV16 + Recurrent and/or Metastatic HNSCC

Who this might be right for
Metastatic Head and Neck CancerRecurrent Head and Neck CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+1 more
PDS Biotechnology Corp. 95
Testing effectiveness (Phase 2)WithdrawnNCT02298595
What this trial is testing

Cetuximab, Cisplatin and BYL719 for HPV-Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Carcinoma, SquamousSquamous Cell CarcinomaOropharyngeal Neoplasms+1 more
Julie E. Bauman, MD, MPH
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06505551
What this trial is testing

Phase 1/2 Study of Autologous SCG142 TCR T Cells in Patients With HPV16/52-positive Carcinoma

Who this might be right for
HPV-Related Squamous Cell CarcinomaHPV-Related Cervical Squamous Cell CarcinomaHPV-Related Vulvar Squamous Cell Carcinoma+4 more
SCG Cell Therapy Pte. Ltd. 66
Testing effectiveness (Phase 2)Ended earlyNCT02706691
What this trial is testing

BGJ398 in Treating Patients With FGFR Positive Recurrent Head and Neck Cancer

Who this might be right for
FGFR Gene AmplificationFGFR1 Gene AmplificationFGFR2 Gene Amplification+7 more
University of Chicago 1
Early research (Phase 1)Study completedNCT02178072
What this trial is testing

Window Trial 5-aza in HNSCC, T-tare

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Yale University 18
Testing effectiveness (Phase 2)Looking for participantsNCT07063212
What this trial is testing

Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)

Who this might be right for
Squamous Cell Carcinoma of Head and NeckSinus CancerNasal Cavity Cancer+9 more
Memorial Sloan Kettering Cancer Center 40
Testing effectiveness (Phase 2)Looking for participantsNCT07497607
What this trial is testing

Reduced Elective Nodal and CTV Dose for HPV+ Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oropharyngeal Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Sara Medek 31
Early research (Phase 1)WithdrawnNCT03575234
What this trial is testing

Nivolumab & IRX-2 With Surgery for Resectable Stage III-IVA Oral Cavity Cancer or HPV-Positive Oropharyngeal Cancer

Who this might be right for
Human Papillomavirus Positive Oropharyngeal Squamous Cell CarcinomaStage II Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7Stage III Oral Cavity Squamous Cell Carcinoma AJCC v6 and v7+2 more
Emory University
Not applicableNot Yet RecruitingNCT07797738
What this trial is testing

Prognostic Biomarkers for Patients With Human Papillomavirus (HPV) Positive Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma (OPSCC)HPVHPV Positive Oropharyngeal Squamous Cell Carcinoma
Abramson Cancer Center at Penn Medicine 30
Testing effectiveness (Phase 2)Study completedNCT02002182
What this trial is testing

ADXS 11-001 Vaccination Prior to Robotic Surgery, HPV-Positive Oropharyngeal Cancer

Who this might be right for
Head and Neck CancerSquamous Cell Carcinoma of the Head and NeckHPV Positive Oropharyngeal Squamous Cell Carcinoma
Andrew Sikora 15
Large-scale testing (Phase 3)Active Not RecruitingNCT03952585
What this trial is testing

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Who this might be right for
Basaloid Squamous Cell CarcinomaClinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+5 more
National Cancer Institute (NCI)
Large-scale testing (Phase 3)UnknownNCT01874171
What this trial is testing

Determination of Cetuximab Versus Cisplatin Early and Late Toxicity Events in HPV+ OPSCC

Who this might be right for
Oropharyngeal Squamous Cell Carcinoma
University of Warwick 334
Large-scale testing (Phase 3)Active Not RecruitingNCT04255849
What this trial is testing

Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living With HIV

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell CarcinomaHIV-1-infectionHPV Infection
Weill Medical College of Cornell University 700
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06759155
What this trial is testing

Phase II Clinical Trial of De-Intensified Therapy in Human Papilloma Virus (HPV) Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
OPSCCOropharyngeal Squamous Cell Carcinoma (SCC)HPV Associated Cancers
University of Vermont Medical Center 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06578871
What this trial is testing

Surgery and Reducing Ionizing Radiation of the Unknown Primary

Who this might be right for
Head and Neck Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 90
Testing effectiveness (Phase 2)Active Not RecruitingNCT05387915
What this trial is testing

Biomarker-Driven Radiation Therapy Dose Reduction After Transoral Robotic Surgery for the Treatment of HPV-Positive Oropharyngeal Cancer

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Oropharyngeal HPV-Positive Squamous Cell Carcinoma
Emory University 33
Not applicableEnded earlyNCT02045186
What this trial is testing

Monitoring of Oral Human Papillomavirus Infection (HPV) in HPV-positive Oropharyngeal Squamous Cell Carcinoma (OPSCC)

Who this might be right for
Carcinoma, Squamous CellHead and Neck NeoplasmsOropharyngeal Neoplasms
UNC Lineberger Comprehensive Cancer Center 1
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