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Results for “Osteosarcoma in Adolescents and Young Adults”

31 trials

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Showing 20 of 31 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT06341712
What this trial is testing

Effects of Maintenance Cabozantinib+BSC Versus BSC in Children and AYA With Osteosarcoma

Who this might be right for
OsteosarcomaOsteosarcoma in ChildrenOsteosarcoma in Adolescents and Young Adults
Ipsen 10
Testing effectiveness (Phase 2)Study completedNCT02304458
What this trial is testing

Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas

Who this might be right for
Metastatic MelanomaRecurrent Ewing Sarcoma/Peripheral Primitive Neuroectodermal TumorRecurrent Hodgkin Lymphoma+20 more
National Cancer Institute (NCI) 140
Testing effectiveness (Phase 2)Temporarily pausedNCT04616560
What this trial is testing

Trastuzumab Deruxtecan for the Treatment of HER2+ Newly Diagnosed or Recurrent Osteosarcoma

Who this might be right for
OsteosarcomaRecurrent Osteosarcoma
National Cancer Institute (NCI) 77
Testing effectiveness (Phase 2)Study completedNCT02432274
What this trial is testing

Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma

Who this might be right for
TumorsSolid Malignant TumorsOsteosarcoma+1 more
Eisai Limited 117
Early research (Phase 1)Temporarily pausedNCT04539366
What this trial is testing

Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, The GD2-CAR PERSIST Trial

Who this might be right for
Recurrent Childhood NeuroblastomaRecurrent Childhood OsteosarcomaRecurrent Neuroblastoma+5 more
National Cancer Institute (NCI) 67
Testing effectiveness (Phase 2)Study completedNCT04154189
What this trial is testing

Compare the Efficacy and Safety of Ifosfamide and Etoposide With or Without Lenvatinib in Children, Adolescents and Young Adults With Relapsed and Refractory Osteosarcoma

Who this might be right for
Osteosarcoma
Eisai Inc. 81
Testing effectiveness (Phase 2)Ended earlyNCT04897880
What this trial is testing

Panobinostat in Pediatric Patients With Solid Tumors Including MRT/ATRT

Who this might be right for
Rhabdoid TumorAtypical Teratoid/Rhabdoid TumorMalignant Rhabdoid Tumor+1 more
Australian & New Zealand Children's Haematology/Oncology Group 25
Early research (Phase 1)Study completedNCT03507491
What this trial is testing

Nab-paclitaxel in Combination with Gemcitabine for Pediatric Relapsed and Refractory Solid Tumors

Who this might be right for
Cancer
Emory University 24
Testing effectiveness (Phase 2)Looking for participantsNCT04851119
What this trial is testing

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Who this might be right for
Colorectal CarcinomaEndometrial CarcinomaMelanoma+19 more
Children's Oncology Group 147
Early research (Phase 1)Ended earlyNCT02536183
What this trial is testing

A Phase I Study of Lyso-thermosensitive Liposomal Doxorubicin and MR-HIFU for Pediatric Refractory Solid Tumors

Who this might be right for
Pediatric CancerSolid TumorsRhabdomyosarcoma+7 more
AeRang Kim 2
Not applicableActive Not RecruitingNCT03496402
What this trial is testing

Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults (MICCHADO)

Who this might be right for
NeuroblastomaRhabdomyosarcomaEwing Sarcoma Family of Tumors+3 more
Institut Curie 600
Testing effectiveness (Phase 2)Study completedNCT05302921
What this trial is testing

Neoadjuvant Dual Checkpoint Inhibition and Cryoablation in Relapsed/Refractory Pediatric Solid Tumors

Who this might be right for
OsteosarcomaEwing SarcomaRhabdomyosarcoma+7 more
Children's National Research Institute 5
Not applicableLooking for participantsNCT05108298
What this trial is testing

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

Who this might be right for
Breast Cancer, NOSCNS Primary Tumor, NOSCervical Cancer, NOS+9 more
Eastern Cooperative Oncology Group 400
Testing effectiveness (Phase 2)Looking for participantsNCT05019703
What this trial is testing

Atezolizumab and Cabozantinib for the Treatment of Adolescents and Young Adults With Recurrent or Metastatic Osteosarcoma, TACOS Study

Who this might be right for
Locally Advanced OsteosarcomaMetastatic OsteosarcomaRecurrent Osteosarcoma+2 more
M.D. Anderson Cancer Center 40
Testing effectiveness (Phase 2)Study completedNCT01848457
What this trial is testing

Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy

Who this might be right for
OsteosarcomaNephrotoxicityOtotoxicity
Children's Hospital of Philadelphia 13
Testing effectiveness (Phase 2)Study completedNCT03320330
What this trial is testing

Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors

Who this might be right for
Recurrent Malignant Solid NeoplasmRecurrent OsteosarcomaRefractory Malignant Solid Neoplasm+1 more
Children's Oncology Group 26
Not applicableStudy completedNCT01674101
What this trial is testing

Effects of Preoperative Physical Therapy in Patients With Lower Extremity Malignancy

Who this might be right for
OsteosarcomaEwing's SarcomaRhabdomyosarcoma+4 more
St. Jude Children's Research Hospital 20
Testing effectiveness (Phase 2)Looking for participantsNCT06625190
What this trial is testing

Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors

Who this might be right for
NeuroblastomaRhabdomyosarcomaSynovial Sarcoma+10 more
University of Florida 27
Testing effectiveness (Phase 2)WithdrawnNCT03811886
What this trial is testing

Natalizumab in Recurrent, Refractory or Progressive Pulmonary Metastatic Osteosarcoma

Who this might be right for
Pulmonary Metastatic Osteosarcoma (pOS)
Case Comprehensive Cancer Center
Testing effectiveness (Phase 2)Ended earlyNCT04730349
What this trial is testing

Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer

Who this might be right for
EpendymomaEwing SarcomaHigh-grade Glioma+7 more
Bristol-Myers Squibb 15
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