Large-scale testing (Phase 3)Looking for participantsNCT06633900What this trial is testingNaltrexone for Overdose PreventionWho this might be right forOverdose Accidental University of California, San Francisco 100
Early research (Phase 1)Study completedNCT07543276What this trial is testingPharmacokinetic (PK) Evaluation of Nalmefene FormulationsWho this might be right forOpioid Overdose Knoa Pharma LLC 13
Not applicableWithdrawnNCT04740099What this trial is testingSurviving Opioid Overdose With Naloxone Education and Resuscitation Trial (SOONER)Who this might be right forOpioid UseOpioid-Related DisordersOpioid Withdrawal+3 more Unity Health Toronto
Post-approval studies (Phase 4)Not Yet RecruitingNCT07485335What this trial is testingA Bundled Intervention to End Opioid OverdosesWho this might be right forOpioid Use DisorderOpioid Overdose University of Alabama at Birmingham 160
Not applicableLooking for participantsNCT05665179What this trial is testingRemoving Barriers: Community Partnering for Innovative Solutions to the Opioid CrisisWho this might be right forOpioid Use DisorderAlcohol Use DisorderHealth Risk Behaviors+3 more University of Michigan 800
Not applicableStudy completedNCT05093309What this trial is testingPreventing Opioid Overdose Deaths by Empowering Pharmacists to Dispense NaloxoneWho this might be right forOpioid Overdose Auburn University 55
Not applicableStudy completedNCT02120612What this trial is testingIncreasing Patient Knowledge of the Signs of Opioid Overdose and Naloxone in a Suburban Treatment ProgramWho this might be right forOpioid DependenceOpioid Use Disorder Edward Hospital 100
Not applicableStudy completedNCT03895827What this trial is testingRecovery Initiation and Management After Overdose (RIMO) ExperimentWho this might be right forOpioid-use Disorder Chestnut Health Systems 251
Not applicableUnknownNCT03845699What this trial is testingDevelopment of an Algorithm That Predicts Hypoventilation Due to an Opioid OverdoseWho this might be right forDrug OverdoseOpioid-Related Disorders RTM Vital Signs, LLC 20
Post-approval studies (Phase 4)UnknownNCT01912573What this trial is testingNasal Naloxone for Narcotic OverdoseWho this might be right forDrug Overdose Judith Feinberg 236
Not applicableStudy completedNCT04589676What this trial is testingDeveloping and Testing the Opioid Rapid Response SystemWho this might be right forOpioid Overdose Real Prevention, LLC 400
Not applicableActive Not RecruitingNCT06523985What this trial is testingThe Feasibility of Using the PulsePoint to Facilitate Overdose Education and Naloxone DistributionWho this might be right forCarrying Naloxone/Narcan on Their Person or in Their VehicleBeing Trained to Respond to an Opioid Overdose Indiana University 5,000
Not applicableStudy completedNCT05506267What this trial is testingDevelopment of a Tracheal Sound SensorWho this might be right forRespiratory InsufficiencyOpioid OverdoseHypoventilation Thomas Jefferson University 20
Early research (Phase 1)Study completedNCT06005402What this trial is testingSafety, Tolerability, and Pharmacokinetics of CSX-1004Who this might be right forOpioid OverdoseOpioid Use Disorder Cessation Therapeutics, Inc. 32
Early research (Phase 1)Study completedNCT05363501What this trial is testingPharmacokinetic Evaluation of a New Naloxone Nasal Swab, Naloxone Nasal Spray, and Intramuscular Naloxone Injection in Healthy VolunteersWho this might be right forOpioid Overdose Pocket Naloxone Corp 76
Not applicableStudy completedNCT03924505What this trial is testingPreventing Opioid Overdose Mortality in the United StatesWho this might be right forOpioid Overdose RTI International 105
Not applicableUnknownNCT03570099What this trial is testingNaloxone Treatment in Skåne County - Effect on Drug-related Mortality and Overdose-related ComplicationsWho this might be right forOpioid Abuse Region Skane 2,000
Not applicableActive Not RecruitingNCT05713695What this trial is testingSupporting Treatment Access and Recovery Through Linkage and SupportWho this might be right forMental Health DisordersSubstance Use Disorders University of Massachusetts, Worcester 208
Not applicableStudy completedNCT05889702What this trial is testingKentucky Access to Recovery EvaluationWho this might be right forSubstance Use DisordersTreatment Adherence and Compliance Terry Bunn 458
Not applicableStudy completedNCT05358132What this trial is testingARM-ED: Advanced Respiratory Monitoring Events in Drug ToxicityWho this might be right forRespiratory InsufficiencyOverdose of OpiateSedative Overdose+1 more NHS Greater Glasgow and Clyde 78