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Results for “PD-1”

2,838 trials

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Showing 20 of 2,838 results

Testing effectiveness (Phase 2)Looking for participantsNCT04165772
What this trial is testing

Study of Induction PD-1 Blockade in Subjects With Locally Advanced Mismatch Repair Deficient Solid Tumors

Who this might be right for
Rectal AdenocarcinomaClinical Stage: Stage II (T3-4, N-)Stage III (Any T, N+)+2 more
Memorial Sloan Kettering Cancer Center 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06620822
What this trial is testing

Efficacy of PD-1 Inhibitor Combination Therapy in Non-small Cell Lung Cancer Patients Who Have Not Achieved Major Pathologic Response After Neoadjuvant Immunotherapy: a Multicenter, Phase II Clinical Trial

Who this might be right for
Non Small Cell Lung Cancer
Shanghai Pulmonary Hospital, Shanghai, China 296
Testing effectiveness (Phase 2)Study completedNCT03647839
What this trial is testing

Modulation Of The Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise With PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer

Who this might be right for
Colorectal Cancer Metastatic
Australasian Gastro-Intestinal Trials Group 90
Large-scale testing (Phase 3)Looking for participantsNCT06989112
What this trial is testing

DESTINY-Endometrial01: A Phase III Study of Trastuzumab Deruxtecan Plus Rilvegostomig or Pembrolizumab as First-Line Treatment of HER2-Expressing (IHC 3+/2+), Mismatch Repair Proficient (pMMR) Endometrial Cancer

Who this might be right for
Endometrial Cancer
AstraZeneca 600
Large-scale testing (Phase 3)Looking for participantsNCT06791512
What this trial is testing

MFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC

Who this might be right for
Colorectal Cancer (CRC)pMMR/MSS Adenocarcinoma of the Colon or Rectum
Jun Huang 166
Early research (Phase 1)Ended earlyNCT02936102
What this trial is testing

FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.

Who this might be right for
Advanced Solid TumorsTriple Negative Breast CancerChordoma and Alveolar Soft Part Sarcoma
Novartis Pharmaceuticals 154
Testing effectiveness (Phase 2)Active Not RecruitingNCT04301557
What this trial is testing

PD1 Antibody Toripalimab and Chemoradiotherapy for dMMR/MSI-H Locally Advanced Colorectal Cancer

Who this might be right for
DMMR Colorectal CancerMSI-H Colorectal CancerLocally Advanced Colorectal Cancer
Sun Yat-sen University 25
Early research (Phase 1)UnknownNCT04122339
What this trial is testing

MAX-10181 Given Orally to Patients With Advanced Solid Tumor

Who this might be right for
Solid Tumor
Maxinovel Pty., Ltd. 30
Testing effectiveness (Phase 2)UnknownNCT05732493
What this trial is testing

Short-course Radiotherapy Combined With Chemotherapy and Pd-1 Inhibitor for Locally Advanced Colon Cancer(TORCH-C)

Who this might be right for
Locally Advanced Colon Cancer
Fudan University 120
Testing effectiveness (Phase 2)WithdrawnNCT04016116
What this trial is testing

Dual PD-1 and JAK2 Inhibition in Hematological Malignancies

Who this might be right for
CancerHematological Malignancy
NYU Langone Health
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07157306
What this trial is testing

Gecacitinib Combined With Donafenib and PD-1 Inhibitor as Immune Rechallenge Therapy for Unresectable Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Tianjin Medical University Cancer Institute and Hospital 35
Early research (Phase 1)Study completedNCT04641871
What this trial is testing

Sym021 in Combination With Either Sym022 or Sym023 or Sym023 and Irinotecan in Patients With Recurrent Advanced Selected Solid Tumor Malignancies

Who this might be right for
Metastatic CancerSolid Tumor
Symphogen A/S 78
Early research (Phase 1)Active Not RecruitingNCT04906044
What this trial is testing

Total Neoadjuvant Treatment Plus PD-1 in Mid-Low Locally Advanced Rectal Cancer

Who this might be right for
TislelizumabLocally Advanced Rectal CancerTotal Neoadjuvant Treatment+1 more
The First Hospital of Jilin University 46
Testing effectiveness (Phase 2)Looking for participantsNCT06576921
What this trial is testing

Efficacy and Safety of Serplulimab Combined With Chemotherapy as Neoadjuvant Treatment for Locally Advanced Gastric Cancer or Adenocarcinoma of Esophagogastric Junction

Who this might be right for
Stomach NeoplasmsImmune Checkpoint Inhibitors
Xijing Hospital 116
Not applicableLooking for participantsNCT06494514
What this trial is testing

NALIRIFOX Combined With PD-1 Sequential Radiotherapy Versus AG Combined With PD-1 Sequential Radiotherapy as First-line Treatment of Locally Advanced Pancreatic Cancer

Who this might be right for
Locally Advanced Pancreatic Cancer
Du Juan 40
Testing effectiveness (Phase 2)UnknownNCT04014101
What this trial is testing

SHR-1210 Plus Apatinib in Patients With Advanced-Stage Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Shanghai Zhongshan Hospital 40
Early research (Phase 1)Active Not RecruitingNCT02521844
What this trial is testing

Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumours

Who this might be right for
Solid Tumors
EDDC (Experimental Drug Development Centre), A*STAR Research Entities 89
Testing effectiveness (Phase 2)UnknownNCT03048500
What this trial is testing

Nivolumab and Metformin Hydrochloride in Treating Patients With Stage III-IV Non-small Cell Lung Cancer That Cannot Be Removed by Surgery

Who this might be right for
Recurrent Non-Small Cell Lung CarcinomaStage III Non-Small Cell Lung CancerStage IIIA Non-Small Cell Lung Cancer+2 more
Northwestern University 17
Large-scale testing (Phase 3)UnknownNCT03884192
What this trial is testing

Consolidation Sintilimab After Concurrent Chemoradiation in Patients With Unresectable Stage III NSCLC

Who this might be right for
Carcinoma, Non-Small Cell Lung
Shandong Cancer Hospital and Institute 162
Large-scale testing (Phase 3)Looking for participantsNCT04365036
What this trial is testing

A Multicenter, Phase 3, Randomized Trial of Sequencial Chemoradiotherapy with or Without Toripalimab (PD-1 Antibody) in Newly Diagnosed Early-Stage Extranodal Natural Killer/T Cell Lymphoma, Nasal Type (ENKTL)

Who this might be right for
NK/T Cell Lymphoma Nos
Sun Yat-sen University 207
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