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Results for “PDL1 Gene Mutation”

45 trials

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Showing 20 of 45 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT04716946
What this trial is testing

Treating Early-stage Non-Small Cell Lung Cancer With Durvalumab and Radiation Therapy

Who this might be right for
NSCLCNon-small Cell Lung CancerLung Cancer+5 more
Memorial Sloan Kettering Cancer Center 13
Not applicableUnknownNCT04191226
What this trial is testing

Genetic Mutation in Recurrent Cervical Cancer

Who this might be right for
Recurrent Cervical CancerNucleotide VariantCopy Number Variation+6 more
Lei Li 300
Testing effectiveness (Phase 2)Study completedNCT04426825
What this trial is testing

Atezolizumab in Combination With Bevacizumab in Patients With EGFR Mutation Positive Stage IIIB-IV Non-Squamous Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Hoffmann-La Roche 23
Very early researchLooking for participantsNCT06305962
What this trial is testing

177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors

Who this might be right for
PDL1 Gene MutationNon Small Cell Lung CancerSmall Cell Lung Cancer ( SCLC )+6 more
Radiopharm Theranostics, Ltd 30
Testing effectiveness (Phase 2)Study completedNCT05330143
What this trial is testing

Study to Evaluate Safety, Tolerance and Efficacy of ASC22 Combined With ART in Subjects With HIV

Who this might be right for
HIV-1-infectionHIV InfectionsPD-L1 Gene Mutation
Ascletis Pharmaceuticals Co., Ltd. 19
Not applicableLooking for participantsNCT06430502
What this trial is testing

Clinical Efficacy of Tumour Treatment Vaccine (TTV) Combined With PD-1 in the Treatment of Relapsed Refractory Advanced Solid Tumours

Who this might be right for
CancerPD-L1 Gene Mutation
Wuxi People's Hospital 200
Early research (Phase 1)Study completedNCT01656642
What this trial is testing

A Phase 1b Study of Atezolizumab in Combination With Vemurafenib or Vemurafenib Plus Cobimetinib in Participants With BRAFV600-Mutation Positive Metastatic Melanoma

Who this might be right for
Malignant Melanoma
Genentech, Inc. 67
Not applicableUnknownNCT05819905
What this trial is testing

Radiomics for prEdiction of lunG cAncer biologY

Who this might be right for
Non Small Cell Lung CancerPET/CTPD-L1+1 more
Poitiers University Hospital 600
Not applicableLooking for participantsNCT06634199
What this trial is testing

Study of Antitumor Immune Response After cCRT and IO Treatment in Non-resectable III Stage NSCLC Patients

Who this might be right for
Non-small Cell Lung Cancer Stage IIIPDL1 Gene Mutation
Fundación GECP 50
Early research (Phase 1)Active Not RecruitingNCT05787587
What this trial is testing

PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsBreast CancerOvarian Cancer+6 more
IDEAYA Biosciences 216
Large-scale testing (Phase 3)Active Not RecruitingNCT03833154
What this trial is testing

Durvalumab With Stereotactic Body Radiation Therapy (SBRT) vs Placebo With SBRT in Early Stage Unresected Non-small Cell Lung Cancer (NSCLC) Patients/ Osimertinib Following SBRT in Patients With Early Stage Unresected NSCLC Harboring an EGFR Mutation

Who this might be right for
Carcinoma, Non-Small-Cell Lung
AstraZeneca 724
Testing effectiveness (Phase 2)UnknownNCT05266937
What this trial is testing

Atezolizumab Plus CArboplatin Plus Nab-paclitaxel

Who this might be right for
Metastatic Breast CancerTriple Negative Breast CancerPD-L1 Gene Mutation
Consorzio Oncotech 49
Not applicableLooking for participantsNCT07618936
What this trial is testing

Programmed Cell Death Ligand 1 PET/CT in Various PD-L1-Related Disease Patients

Who this might be right for
PD-L1 Gene MutationPD-L1 Gene AmplificationPD-L1-related Disease+1 more
Tianjin Medical University 500
Testing effectiveness (Phase 2)UnknownNCT04023916
What this trial is testing

Sintilimab Plus R-CHOP as the First-line Treatment in Patients With Diffuse Large B-Cell Lymphoma.

Who this might be right for
Diffuse Large B-Cell LymphomaSintilimabTP53 Mutation
Chinese Academy of Medical Sciences 30
Not applicableUnknownNCT04405661
What this trial is testing

Correlation Between Specific Gene Mutationand Local Immune Microenvironment and Immunotherapy Efficacy in NSCLC

Who this might be right for
NSCLC
Guangzhou Institute of Respiratory Disease 100
Testing effectiveness (Phase 2)WithdrawnNCT04754815
What this trial is testing

Study of Pembrolizumab With Single Agent Chemotherapy in Elderly Patients With Advanced NSCLC

Who this might be right for
Non Small Cell Lung CancerAdvanced Lung Non-Small Cell CarcinomaPD-L1 Gene Mutation
Shirish Gadgeel
Testing effectiveness (Phase 2)Active Not RecruitingNCT05445843
What this trial is testing

Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation.

Who this might be right for
Locally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation
Novartis Pharmaceuticals 95
Testing effectiveness (Phase 2)UnknownNCT03491345
What this trial is testing

K-Basket, Avelumab, Biomarker-driven, Advanced Solid Tumor

Who this might be right for
PD-L1 Positive Mutation TumorEBV Positive Mutation TumorMSI-H Mutation Tumor+1 more
Yonsei University 60
Testing effectiveness (Phase 2)Looking for participantsNCT07807163
What this trial is testing

A Study Evaluating Ficerafusp Alfa (BCA101) QW in Combination With Pembrolizumab vs Alternative Ficerafusp Alfa Dosing in 1L R or M HNSCC

Who this might be right for
Metastatic Head and Neck Squamous Cell CarcinomaRecurrent Head and Neck Squamous Cell Carcinoma
Bicara Therapeutics 160
Not applicableActive Not RecruitingNCT06876402
What this trial is testing

Gene Molecular Alterations as Disease Prognostic Markers in Patients With Non-small Cell Lung Cancer (NSCLC)

Who this might be right for
NSCLC (Non-small Cell Lung Cancer)
Hellenic Cooperative Oncology Group 367
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