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Results for “PK, PD, and Safety”

707 trials

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Showing 20 of 707 results

Early research (Phase 1)Looking for participantsNCT07399678
What this trial is testing

Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

Who this might be right for
Overweight or Obese AdultsOverweight or Obese, Type 2 Diabetes
Alveus Therapeutics, Inc. 180
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07154485
What this trial is testing

Investigator Initiated Study for the Safety and Efficacy in Frontotemporal Dementia

Who this might be right for
Dementia Frontotemporal
Hee-Jin Kim 15
Early research (Phase 1)Study completedNCT05225584
What this trial is testing

Safety, PK, PD, Clinical Activity of KT-333 in Adult Patients With Refractory Lymphoma, Large Granular Lymphocytic Leukemia, Solid Tumors

Who this might be right for
Non Hodgkin Lymphoma (NHL)Peripheral T-cell Lymphoma (PTCL)Cutaneous T-Cell Lymphoma (CTCL)+3 more
Kymera Therapeutics, Inc. 56
Early research (Phase 1)Study completedNCT01899755
What this trial is testing

Evaluate the Pharmacokinetics (PK), Safety and Tolerability, Immunogenicity, and Pharmacodynamics (PD) of GSK2800528 in Healthy Subjects.

Who this might be right for
Psoriasis
GlaxoSmithKline 45
Early research (Phase 1)Study completedNCT05784155
What this trial is testing

To Evaluate the PK, PD, Safety and Drug Tolerance of JW0302 in Healthy Volunteers

Who this might be right for
Healthy
JW Pharmaceutical 44
Testing effectiveness (Phase 2)Ended earlyNCT02221947
What this trial is testing

Study to Evaluate the Preliminary Safety, Efficacy, PK and PD of Bryostatin 1 in Patients With Alzheimer's Disease

Who this might be right for
Alzheimer's Disease
Neurotrope Bioscience, Inc. 9
Early research (Phase 1)Study completedNCT06491550
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4144 as Well as the Impact of AZD4144 on the Pharmacokinetics of Rosuvastatin and Furosemide in Healthy Participants

Who this might be right for
Healthy Participants
AstraZeneca 91
Early research (Phase 1)Not Yet RecruitingNCT07797907
What this trial is testing

This Clinical Study is to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Preliminary Antitumor Activity of BD200 in Participants With Advanced or Metastatic Cancer.

Who this might be right for
Solid Tumor (Phase I)
Biolojic Design Ltd. 110
Early research (Phase 1)Study completedNCT05198778
What this trial is testing

A Safety, PK, PD and Food Effect Study of URC102 in Healthy Adults and Patients With Renal Impairment

Who this might be right for
Healthy, Renal Impairment
JW Pharmaceutical 28
Early research (Phase 1)Study completedNCT02582840
What this trial is testing

The PK and PD of Dapagliflozin Therapy in Combination With Insulin in Japanese Subjects With T1DM

Who this might be right for
Type 1 Diabetes Mellitus
AstraZeneca 42
Early research (Phase 1)Study completedNCT02629874
What this trial is testing

PK/PD of EA-230 During Endotoxemia

Who this might be right for
EndotoxemiaSystemic Inflammatory Response
Radboud University Medical Center 60
Large-scale testing (Phase 3)Active Not RecruitingNCT06847724
What this trial is testing

Comparative PK, PD, Efficacy, and Safety Assessment of the Proposed Ocrelizumab Biosimilar CYB704 and Ocrevus in Participants With Relapsing Multiple Sclerosis

Who this might be right for
Relapsing Multiple Sclerosis
Sandoz 183
Early research (Phase 1)Study completedNCT03346330
What this trial is testing

Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), Food-effect of TRK-750

Who this might be right for
Healthy, Peripheral Neuropathic Pain
Toray Industries, Inc 105
Early research (Phase 1)Study completedNCT01560481
What this trial is testing

Clinical Trial to Evaluate Safety and pK Profile of Metformin Glycinate in Healthy Volunteers

Who this might be right for
Healthy
Laboratorios Silanes S.A. de C.V. 49
Early research (Phase 1)Study completedNCT02828046
What this trial is testing

An Ascending Dose Study to Evaluate M281 Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD)

Who this might be right for
Healthy Volunteers
Momenta Pharmaceuticals, Inc. 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT06965413
What this trial is testing

Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity

Who this might be right for
ObesityOverweightOverweight With One Weight Related Comorbidity
Hoffmann-La Roche 285
Early research (Phase 1)Study completedNCT02195167
What this trial is testing

Dasotraline SEP360-105 Pediatric PK/PD Study

Who this might be right for
Pediatric Attention Deficit Hyperactivity Disorder
Sumitomo Pharma America, Inc. 105
Testing effectiveness (Phase 2)Study completedNCT01121731
What this trial is testing

A Phase I/II Clinical Trial With Interferon Alfa 5 in Treatment-Experienced Patients With Genotype-1 Chronic Hepatitis C

Who this might be right for
Chronic Hepatitis C Virus InfectionGenotype 1Treatment-Experienced Patients+1 more
Digna Biotech S.L. 70
Early research (Phase 1)Study completedNCT01496937
What this trial is testing

First-in-Human Exploratory Single Ascending Dose of GLPG0974

Who this might be right for
Healthy
Lakefront Biotherapeutics NV 32
Early research (Phase 1)Study completedNCT02285101
What this trial is testing

Recombinant Human Arginase 1 (rhArg1) in Patients With Advanced Arginine Auxotrophic Solid Tumors

Who this might be right for
MelanomaProstate Adenocarcinoma
Bio-Cancer Treatment International Limited 23
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