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Results for “PK, PD, and Safety”

696 trials

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Showing 20 of 696 results

Testing effectiveness (Phase 2)Study completedNCT03665285
What this trial is testing

A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsLung CancerBreast Cancer+6 more
NextCure, Inc. 109
Early research (Phase 1)Study completedNCT05523570
What this trial is testing

Evaluate the Safety, Tolerability, PK and PD of HNC364 Injectable Suspension

Who this might be right for
Parkinson's Disease
Guangzhou Henovcom Bioscience Co. Ltd. 34
Large-scale testing (Phase 3)Study completedNCT05378672
What this trial is testing

Inv. Safety, Efficacy & PD of Dasiglucagon as Hypoglycemia Rescue Therapy in Children <6 Years With T1D

Who this might be right for
HypoglycemiaType 1 Diabetes
Zealand Pharma 8
Testing effectiveness (Phase 2)Study completedNCT03928353
What this trial is testing

Study to Evaluate the Safety, Tolerability, PK and PD of PB2452 in Healthy Younger, Older and Elderly Subjects

Who this might be right for
Healthy
SFJ Pharmaceuticals, Inc. 23
Early research (Phase 1)Looking for participantsNCT07182656
What this trial is testing

Safety, Tolerability, and PK/PD of CIGB-814 in Chinese Health Participants

Who this might be right for
Rheumatoid Arthritis (RA)
Yi Fang 70
Early research (Phase 1)Study completedNCT05745883
What this trial is testing

Study of DISC-0974 to Assess the Safety, Tolerability, PK and PD of DISC-0974 in Participants With CKD and Anemia

Who this might be right for
Chronic Kidney DiseasesAnemia of Chronic Kidney Disease
Disc Medicine, Inc 55
Testing effectiveness (Phase 2)Ended earlyNCT00458861
What this trial is testing

BG9924 in Combination With Methotrexate for Participants With Active Rheumatoid Arthritis

Who this might be right for
Rheumatoid Arthritis
Biogen 115
Testing effectiveness (Phase 2)Study completedNCT03663335
What this trial is testing

Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Kidney Transplant Recipients

Who this might be right for
Kidney Transplantation
Novartis Pharmaceuticals 418
Early research (Phase 1)Active Not RecruitingNCT05167071
What this trial is testing

HBM4003 Combine With Toripalimab in Patients With Advanced NEN and Other Solid Tumors Study

Who this might be right for
Solid TumorsNeuroendocrine TumorsCRC
Harbour BioMed (Guangzhou) Co. Ltd. 53
Early research (Phase 1)Study completedNCT03579030
What this trial is testing

Safety and PK/PD of RTA 1701 in Healthy Adults

Who this might be right for
Healthy
Biogen 90
Early research (Phase 1)Study completedNCT05006521
What this trial is testing

Single and Multiple Ascending Dose Study of KN-002

Who this might be right for
Asthma COPD
Kinaset Therapeutics Inc 117
Early research (Phase 1)Study completedNCT03724916
What this trial is testing

Evaluate the Safety, Pharmacokinetics (PK), and Pharmacodynamics (PD) of TAK-079 in Combination With Standard Background Therapy in Participants With Moderate to Severe Systemic Lupus Erythematosus (SLE)

Who this might be right for
Systemic Lupus ErythematosusLupus Erythematosus, Systemic
Millennium Pharmaceuticals, Inc. 23
Early research (Phase 1)Study completedNCT03062956
What this trial is testing

A Single Ascending Dose Study Assessing the Safety, Tolerability, PK and PD of MYK-491

Who this might be right for
Dilated Cardiomyopathy
MyoKardia, Inc. 64
Testing effectiveness (Phase 2)Ended earlyNCT00607451
What this trial is testing

Safety, Tolerability, PK and PD Study of Neu-120 in the Treatment of Levodopa-induced Dyskinesia

Who this might be right for
Levodopa-induced Dyskinesia
Neurim Pharmaceuticals Ltd. 8
Large-scale testing (Phase 3)Ended earlyNCT06121375
What this trial is testing

Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy

Who this might be right for
Biliary Atresia
Intercept Pharmaceuticals 28
Testing effectiveness (Phase 2)Looking for participantsNCT06938867
What this trial is testing

Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

Who this might be right for
E Coli InfectionsAllogenic Transplant Patients
SNIPR Biome Aps. 24
Testing effectiveness (Phase 2)Study completedNCT02079896
What this trial is testing

Lexaptepid Pegol (NOX-H94) in ESA-hyporesponsive Anemia in Dialysis Patients

Who this might be right for
AnemiaEnd Stage Renal Disease
TME Pharma AG 33
Early research (Phase 1)Study completedNCT01156779
What this trial is testing

Study to Evaluate Safety and PK/PD of DA-3091 in Healthy Male Subjects

Who this might be right for
Diabetes Mellitus
Dong-A Pharmaceutical Co., Ltd. 31
Early research (Phase 1)Study completedNCT03586908
What this trial is testing

PK/PD, Safety and Tolerability of PHP-201 Topical Eye Drop in Korean and Japanese Healthy Subjects

Who this might be right for
Healthy Volunteer
pH Pharma 24
Early research (Phase 1)Active Not RecruitingNCT05501717
What this trial is testing

Safety, PK/PD, and Immunogenicity Study of SC ALXN2030 in Healthy Participants

Who this might be right for
Healthy
Alexion Pharmaceuticals, Inc. 48
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