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Results for “PK, PD, and Safety”

681 trials

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Showing 20 of 681 results

Testing effectiveness (Phase 2)UnknownNCT01364155
What this trial is testing

Safety, Tolerability, PK, and PD of LIM-0705 in Subjects With Impaired Glucose Tolerance or Abnormal HOMA-IR

Who this might be right for
Impaired Glucose ToleranceInsulin Resistance
Limerick BioPharma 50
Testing effectiveness (Phase 2)Ended earlyNCT03781414
What this trial is testing

Study of Efficacy, Safety, Tolerability, Pharmacokinetic (PK) and Pharmacodynamic (PD) of an Anti-CD40 Monoclonal Antibody, CFZ533, in Liver Transplant Recipients With Additional 12-month Follow-up and Long-term Extension

Who this might be right for
Liver Transplant Rejection
Novartis Pharmaceuticals 129
Very early researchUnknownNCT03673215
What this trial is testing

The Tolerability，Safety，PK/PD Study of rhTPO in the Patients With Liver Function Impairment

Who this might be right for
Liver Cirrhosis
Shenyang Sunshine Pharmaceutical Co., LTD. 58
Testing effectiveness (Phase 2)Study completedNCT02455011
What this trial is testing

Dose Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of REMD-477 in Subjects With Type 2 Diabetes Mellitus

Who this might be right for
Type 2 Diabetes MellitusDiabetes
REMD Biotherapeutics, Inc. 75
Early research (Phase 1)Study completedNCT05005520
What this trial is testing

Study of DTRI-031 in Healthy Volunteers

Who this might be right for
Healthy VolunteersPharmacokineticsPharmacodynamics
Basking Biosciences, Inc. 46
Testing effectiveness (Phase 2)Study completedNCT01743768
What this trial is testing

Safety, Efficacy, PK, and PD Characteristics of Orally Inhaled SB010 in Male Patients With Mild Asthma (Multiple Dose)

Who this might be right for
Asthma
Sterna Biologicals GmbH & Co. KG 38
Early research (Phase 1)Study completedNCT01684150
What this trial is testing

A Phase 1, Open-Label, Dose-Escalation & Expanded Cohort, Continuous IV Infusion, Multi-center Study of the Safety, Tolerability,PK & PD of EPZ-5676 in Treatment Relapsed/Refractory Patients With Leukemias Involving

Who this might be right for
Acute Myeloid LeukemiaAcute Lymphoblastic LeukemiaMyelodysplastic Syndrome+1 more
Epizyme, Inc. 51
Early research (Phase 1)Not Yet RecruitingNCT07352423
What this trial is testing

Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Study of ALXN2230 in Healthy Participants

Who this might be right for
Healthy Adult Participants
Alexion Pharmaceuticals, Inc. 48
Early research (Phase 1)Study completedNCT05095168
What this trial is testing

Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of a Single Ascending Dose (SAD) of CAN106 Administered Intravenously (IV) in Healthy Subjects

Who this might be right for
PNH
CARE Pharma Shanghai Ltd. 31
Early research (Phase 1)Study completedNCT00480818
What this trial is testing

Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamics of SAM-531 in Healthy Young and Elderly Subjects

Who this might be right for
Alzheimer Disease
Wyeth is now a wholly owned subsidiary of Pfizer 80
Early research (Phase 1)Study completedNCT02616861
What this trial is testing

Trial of IW-1973 (A Stimulator of Soluble Guanylate Cyclase (sGC)) in Healthy Volunteers

Who this might be right for
Healthy
Cyclerion Therapeutics 54
Testing effectiveness (Phase 2)Study completedNCT06542614
What this trial is testing

Treatment of Moderate to Severe Plaque Psoriasis

Who this might be right for
Plaque Psoriasis
Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. 209
Testing effectiveness (Phase 2)Study completedNCT01965509
What this trial is testing

A PK/PD Study of Polyethylene Glycol Loxenatide in Patients With Type 2 Diabetes

Who this might be right for
Type 2 Diabetes
Jiangsu HengRui Medicine Co., Ltd. 120
Testing effectiveness (Phase 2)Ended earlyNCT03573544
What this trial is testing

This Study is to Evaluate Safe and Effective Treatment Dose of OBI-888 in Patients With Locally Advanced or Metastatic Solid Tumors.

Who this might be right for
Metastatic Solid TumorsLocally Advanced Solid Tumors
OBI Pharma, Inc 54
Early research (Phase 1)Study completedNCT05298787
What this trial is testing

SAD/MAD Study of RLS-0071 in Healthy Volunteers in Support of a COVID-19 Development Program

Who this might be right for
Healthy Volunteer
ReAlta Life Sciences, Inc. 56
Early research (Phase 1)Ended earlyNCT03880487
What this trial is testing

A Single and Multiple Ascending Dose Study in Healthy Subjects to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of KP-1199

Who this might be right for
Analgesia
Kalyra Pharmaceuticals, Inc. 26
Early research (Phase 1)Study completedNCT01051505
What this trial is testing

Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Ascending Doses of AZD5069 in Healthy Volunteers

Who this might be right for
Healthy
AstraZeneca 8
Early research (Phase 1)Study completedNCT03488186
What this trial is testing

PK-PD Comparative Study of Lansoprazole Capsules and Lansoprazole Enteric-coated Capsules in Healthy Chinese Volunteers

Who this might be right for
Effect of DrugsSafety Issues
First Affiliated Hospital of Zhejiang University 24
Early research (Phase 1)Study completedNCT03446053
What this trial is testing

Evaluate the Safety, PK, PD, Immunogenicity of N-Rephasin® SAL200 in Healthy Male Volunteers

Who this might be right for
Healthy VolunteersAnti-Bacterial AgentsMethicillin-Resistant Staphylococcus Aureus+1 more
Intron Biotechnology, Inc. 33
Testing effectiveness (Phase 2)Study completedNCT01121731
What this trial is testing

A Phase I/II Clinical Trial With Interferon Alfa 5 in Treatment-Experienced Patients With Genotype-1 Chronic Hepatitis C

Who this might be right for
Chronic Hepatitis C Virus InfectionGenotype 1Treatment-Experienced Patients+1 more
Digna Biotech S.L. 70
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