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Results for “POLE Gene Mutation”

9 trials

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Showing 9 of 9 results

Not applicableEnrolling By InvitationNCT06409039
What this trial is testing

POLE-END REAL LIFE: Endometrial Cancer Early Stages I-II and Advanced Stages III and IV Evaluation of POLE as a Prognostic Factor. Participants Are Women >= 18 Years Old, With the Pole Mutation

Who this might be right for
Endometrial Neoplasms
Azienda Ulss 2 Marca Trevigiana 80
Not applicableLooking for participantsNCT05420064
What this trial is testing

An Intervention to Increase Genetic Testing in Families Who May Share a Gene Mutation Related to Cancer Risk and An Intervention to Help Patients and Their Primary Care Providers Stay Up-to-date About Uncertain Genetic Test Results

Who this might be right for
BRCA1 MutationPOLD1 Gene MutationCDKN2A Mutation+19 more
Memorial Sloan Kettering Cancer Center 1,000
Testing effectiveness (Phase 2)Study completedNCT03012581
What this trial is testing

Secured Access to Nivolumab for Adult Patients With Selected Rare Cancer Types

Who this might be right for
Carcinoma, Renal CellHead and Neck NeoplasmSkin Neoplasms+3 more
UNICANCER 269
Not applicableLooking for participantsNCT05103969
What this trial is testing

Cohort of Tumors With POLE/D1 Mutation

Who this might be right for
TumorsPOLE Exonuclease Domain MutationPOLD1 Gene Mutation
Federation Francophone de Cancerologie Digestive 100
Testing effectiveness (Phase 2)UnknownNCT03810339
What this trial is testing

Toripalimab as Monotherapy in Participants With POLE or POLD-1 Mutated and Non-MSI-H Advanced Solid Tumors

Who this might be right for
Solid TumorAdvanced Cancer
Sun Yat-sen University 35
Testing effectiveness (Phase 2)UnknownNCT03150706
What this trial is testing

Avelumab for MSI-H or POLE Mutated Metastatic Colorectal Cancer

Who this might be right for
Metastatic Colorectal Cancer
Asan Medical Center 33
Testing effectiveness (Phase 2)Looking for participantsNCT03428802
What this trial is testing

Pembrolizumab in Treating Participants With Metastatic, Recurrent or Locally Advanced Cancer and Genomic Instability

Who this might be right for
BRCA1 Gene MutationBRCA2 Gene MutationLocally Advanced Solid Neoplasm+17 more
Rutgers, The State University of New Jersey 40
Testing effectiveness (Phase 2)UnknownNCT03491345
What this trial is testing

K-Basket, Avelumab, Biomarker-driven, Advanced Solid Tumor

Who this might be right for
PD-L1 Positive Mutation TumorEBV Positive Mutation TumorMSI-H Mutation Tumor+1 more
Yonsei University 60
Not applicableLooking for participantsNCT07114653
What this trial is testing

The Role of POLE Mutation in High Risk Endometrial Cancer.

Who this might be right for
Endometrial Neoplasms
Far Eastern Memorial Hospital 150