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Results for “Paroxysmal Nocturnal Hemoglobinuria”

190 trials

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Showing 20 of 190 results

Large-scale testing (Phase 3)Looking for participantsNCT06932471
What this trial is testing

Study of Safety and Efficacy of MY008211A in Patients With Residual Anemia Despite Anti-C5 Antibody Treatment

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Wuhan Createrna Science and Technology Co., Ltd 20
Early research (Phase 1)Looking for participantsNCT07256301
What this trial is testing

A Phase Ib, Multicenter, Open-Label Study of Multiple-Dose EA5 in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
PNH - Paroxysmal Nocturnal Hemoglobinuria
Shanghai Lanyi Therapeutics Co., Ltd. 24
Testing effectiveness (Phase 2)Looking for participantsNCT06745622
What this trial is testing

Long-term Safety and Tolerability of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Haisco Pharmaceutical Group Co., Ltd. 47
Not applicableStudy completedNCT00856388
What this trial is testing

Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders

Who this might be right for
Accelerated Phase Chronic Myelogenous LeukemiaAcute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic SyndromeAdult Acute Lymphoblastic Leukemia in Remission+97 more
Roswell Park Cancer Institute 62
Testing effectiveness (Phase 2)UnknownNCT01760096
What this trial is testing

Safety and Efficacy of Levamisole Combined With Cyclosporine A in Patients With Subclinical Paroxysmal Nocturnal Hemoglobinuria and PNH in the Setting of Another Bone Marrow Failure Syndromes(PNH-2013)

Who this might be right for
Paroxysmal Nocturnal HemoglobinuriaHemoglobinuriaHemoglobinuria, Paroxysmal+6 more
Institute of Hematology & Blood Diseases Hospital, China 50
Large-scale testing (Phase 3)Study completedNCT04058158
What this trial is testing

Compare SB12 (Proposed Eculizumab Biosimilar) to Soliris in Subjects With Paroxysmal Nocturnal Haemoglobinuria

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Samsung Bioepis Co., Ltd. 50
Large-scale testing (Phase 3)Study completedNCT04558918
What this trial is testing

Study of Efficacy and Safety of Twice Daily Oral LNP023 in Adult PNH Patients With Residual Anemia Despite Anti-C5 Antibody Treatment

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Novartis Pharmaceuticals 97
Testing effectiveness (Phase 2)Study completedNCT02591862
What this trial is testing

Coversin in Paroxysmal Nocturnal Haemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Haemoglobinuria (PNH)
AKARI Therapeutics 1
Testing effectiveness (Phase 2)Study completedNCT00397813
What this trial is testing

Fludarabine Phosphate and Total Body Irradiation Followed by a Donor Peripheral Stem Cell Transplant in Treating Patients With Myelodysplastic Syndromes or Myeloproliferative Disorders

Who this might be right for
Atypical Chronic Myeloid Leukemia, BCR-ABL1 NegativeChronic Myelomonocytic Leukemiade Novo Myelodysplastic Syndrome+11 more
Fred Hutchinson Cancer Center 77
Large-scale testing (Phase 3)Study completedNCT03056040
What this trial is testing

ALXN1210 Versus Eculizumab in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Eculizumab

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Alexion Pharmaceuticals, Inc. 202
Large-scale testing (Phase 3)Looking for participantsNCT06932744
What this trial is testing

Study of Safety and Efficacy of MY008211A in Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Who Are Naive to Complement Inhibitor Therapy

Who this might be right for
Paroxysmal Nocturnal Haemoglobinuria (PNH)
Wuhan Createrna Science and Technology Co., Ltd 66
Not applicableStudy completedNCT01364363
What this trial is testing

Unrelated Donor Stem Cell Transplantation

Who this might be right for
Severe Aplastic AnemiaParoxysmal Nocturnal HemoglobinuriaAcute Myelogenous Leukemia+10 more
Scripps Health 64
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07387302
What this trial is testing

SLN12140 in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) in China

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Linno Pharmaceuticals, Inc. 10
Not applicableStudy completedNCT04671810
What this trial is testing

Prospective Observational Study of Long-term Pathogenic Treatment of Elizaria®

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
AO GENERIUM 44
Testing effectiveness (Phase 2)Study completedNCT00587054
What this trial is testing

Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic Disorders

Who this might be right for
Allogeneic Stem Cell TransplantLeukemiaNon-Hodgkins+3 more
Memorial Sloan Kettering Cancer Center 129
Testing effectiveness (Phase 2)Study completedNCT06561841
What this trial is testing

Evaluate the Efficacy and Safety of HSK39297 in Patients With Paroxysmal Nocturnal Hemoglobinuria（PNH）

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Haisco Pharmaceutical Group Co., Ltd. 47
Not applicableActive Not RecruitingNCT05776472
What this trial is testing

A Real World Effectiveness Study of Pegcetacoplan in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria
Swedish Orphan Biovitrum 165
Early research (Phase 1)Study completedNCT06490991
What this trial is testing

Comparison of HRS-5965 Capsules and Tablets in Healthy Subjects

Who this might be right for
Paroxysmal Nocturnal Hemoglobinuria，IgA Nephropathy
Chengdu Suncadia Medicine Co., Ltd. 16
Large-scale testing (Phase 3)Study completedNCT00122304
What this trial is testing

Study of Safety in Hemolytic Paroxysmal Nocturnal Hemoglobinuria (PNH) Patients Treated With Eculizumab

Who this might be right for
Hemoglobinuria, Paroxysmal
Alexion Pharmaceuticals, Inc. 85
Early research (Phase 1)Study completedNCT03316521
What this trial is testing

First-In-Human Clinical Study of the C3 Complement Inhibitor AMY- 101 in Healthy Male Volunteers

Who this might be right for
Complement Mediated Diseases
Amyndas Pharmaceuticals S.A. 50
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