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Results for “Participants With Moderate Hepatic Impairment”

Showing 20 of 0 results

Early research (Phase 1)Study completedNCT06860243
What this trial is testing

Evaluate Opevesostat (MK-5684) in Male Participants With Moderate Hepatic Impairment (MK-5684-009)

Who this might be right for
Hepatic ImpairmentHealthy Participants
Merck Sharp & Dohme LLC 16
Early research (Phase 1)Study completedNCT05437120
What this trial is testing

Pharmacokinetics and Safety Assessment of VX-121/Tezacaftor/Deutivacaftor in Participants With Moderate Hepatic Impairment

Who this might be right for
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated 16
Early research (Phase 1)Study completedNCT06952634
What this trial is testing

An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage

Who this might be right for
Hepatic Impairment
Alumis Inc 32
Early research (Phase 1)Ended earlyNCT05517226
What this trial is testing

Pharmacokinetics of Cotadutide in Participants With Hepatic Impairment

Who this might be right for
Hepatic Impairment
AstraZeneca 24
Early research (Phase 1)Study completedNCT04473664
What this trial is testing

Quizartinib Pharmacokinetics in Participants With Moderate Hepatic Impairment

Who this might be right for
Hepatic ImpairmentModerate Impaired Hepatic Function
Daiichi Sankyo 12
Early research (Phase 1)Study completedNCT05224609
What this trial is testing

Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction

Who this might be right for
Moderate Hepatic ImpairmentSevere Hepatic ImpairmentHealthy Volunteers
Pfizer 21
Early research (Phase 1)Not Yet RecruitingNCT07609706
What this trial is testing

The Combination of Belantamab Mafodotin, Bortezomib, and Dexamethasone (BVd) in Participants With Multiple Myeloma and Moderate Hepatic Impairment

Who this might be right for
Multiple Myeloma
GlaxoSmithKline 20
Early research (Phase 1)Study completedNCT05078580
What this trial is testing

Pharmacokinetic (PK) and Safety Study of Iptacopan (LNP023) in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Matched Control Healthy Participants With Normal Hepatic Function.

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 38
Early research (Phase 1)Study completedNCT05610657
What this trial is testing

A Pharmacokinetic Study of Mitapivat in Participants With Moderate Hepatic Impairment Compared to Matched Healthy Control Participants With Normal Hepatic Function

Who this might be right for
Moderate Hepatic Impairment
Agios Pharmaceuticals, Inc. 20
Early research (Phase 1)Looking for participantsNCT04617522
What this trial is testing

Study of Sacituzumab Govitecan in Participants With Advanced or Metastatic Solid Tumor and Moderate Liver Impairment

Who this might be right for
Advanced or Metastatic Solid TumorLiver Failure
Gilead Sciences 30
Early research (Phase 1)Looking for participantsNCT07343960
What this trial is testing

A Phase I Study to Investigate the Pharmacokinetics and Safety of Capivasertib in Participants With Moderate Hepatic Impairment

Who this might be right for
Moderate Hepatic Impairment
AstraZeneca 20
Early research (Phase 1)UnknownNCT04631549
What this trial is testing

An Investigational Study of SHR3680 in Participants With Mild to Moderate Liver Impairment and Healthy Participants

Who this might be right for
Hepatic ImpairmentHealthy Participants
Jiangsu HengRui Medicine Co., Ltd. 24
Early research (Phase 1)Study completedNCT04515641
What this trial is testing

Single-Dose Islatravir in Moderate Hepatic Impairment (MK-8591-030)

Who this might be right for
Human Immunodeficiency Virus (HIV) Infection
Merck Sharp & Dohme LLC 12
Early research (Phase 1)UnknownNCT04631575
What this trial is testing

An Investigational Study of SHR6390 in Participants With Mild to Moderate Liver Impairment and Healthy Participants

Who this might be right for
Hepatic ImpairmentHealthy Participants
Jiangsu HengRui Medicine Co., Ltd. 24
Early research (Phase 1)Study completedNCT01512693
What this trial is testing

Assessment of Pharmacokinetics of Single Dose Odanacatib (MK-0822) in Participants With Moderate Hepatic Insufficiency (MK-0822-070)

Who this might be right for
Hepatic Insufficiency
Merck Sharp & Dohme LLC 17
Early research (Phase 1)Study completedNCT05674474
What this trial is testing

Vorasidenib in Participants With Moderate or Mild Hepatic Impairment and Matched Participants With Normal Hepatic Function

Who this might be right for
Hepatic Impairment
Institut de Recherches Internationales Servier 16
Early research (Phase 1)Study completedNCT05329623
What this trial is testing

Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants.

Who this might be right for
Small Cell Lung Carcinoma
Novartis Pharmaceuticals 33
Early research (Phase 1)Study completedNCT04995484
What this trial is testing

Belzutifan (MK-6482) in Participants With Hepatic Impairment (MK-6482-020)

Who this might be right for
Moderate Hepatic Impairment
Merck Sharp & Dohme LLC 17
Early research (Phase 1)Study completedNCT04482270
What this trial is testing

Investigate the Effect of Mild and Moderate Hepatic Impairment on the Safety and Tolerability of Fezolinetant Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic ImpairmentHealthy Volunteers
Astellas Pharma Global Development, Inc. 26
Early research (Phase 1)Study completedNCT05707390
What this trial is testing

Mezigdomide in Healthy Participants and Participants With Hepatic Impairment

Who this might be right for
Hepatic Impairment
Bristol-Myers Squibb 32
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