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Results for “Participants With Moderate Hepatic Impairment”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT02910739
What this trial is testing

An Open-Label Study Investigating MK-8931 in Participants With Mild and Moderate Hepatic Insufficiency (MK-8931-016)

Who this might be right for
Amnestic Mild Cognitive ImpairmentAlzheimer's DiseaseProdromal Alzheimer's Disease
Merck Sharp & Dohme LLC 16
Early research (Phase 1)Looking for participantsNCT07231991
What this trial is testing

Learn How the Body Processes the Study Medicine Called Vepdegestrant in People With Loss of Liver Function

Who this might be right for
Healthy Participants
Pfizer 24
Early research (Phase 1)Study completedNCT05386589
What this trial is testing

Evaluate Molnupiravir (MK-4482) in Participants With Moderate Hepatic Impairment (MK-4482-016)

Who this might be right for
Hepatic Impairment
Merck Sharp & Dohme LLC 14
Early research (Phase 1)Study completedNCT07018492
What this trial is testing

Phase 1 Study of BPN14770 in Participants With Hepatic Impairment and Healthy Controls

Who this might be right for
Hepatic Impairment
Shionogi 32
Early research (Phase 1)Study completedNCT07198087
What this trial is testing

Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy Participants

Who this might be right for
Primary Central Nervous System Lymphoma (PCNSL)
Ono Pharmaceutical Co., Ltd. 40
Testing effectiveness (Phase 2)Looking for participantsNCT06682988
What this trial is testing

Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine

Who this might be right for
Advanced High-Grade Epithelial Ovarian CancerPrimary Peritoneal CancerFallopian Tube Cancers
AbbVie 110
Very early researchStudy completedNCT04223635
What this trial is testing

Study of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy Participants

Who this might be right for
Moderate Hepatic Impairment
Daiichi Sankyo 16
Early research (Phase 1)Ended earlyNCT04241835
What this trial is testing

Compare the Blood Levels and Safety of Tazemetostat in Participants With Advanced Cancer and Moderate/Severe Liver Impairment to Participants With Advanced Cancer and Normal Liver Function

Who this might be right for
Hepatic ImpairmentAdvanced Malignant Solid Tumor
Epizyme, Inc. 18
Early research (Phase 1)Study completedNCT01531309
What this trial is testing

Pharmacokinetics of AGO178 in Participants With Liver Impairment

Who this might be right for
Hepatic Impairment
Novartis Pharmaceuticals 32
Early research (Phase 1)Ended earlyNCT04136444
What this trial is testing

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

Who this might be right for
Healthy Study ParticipantsImpaired Hepatic Function
UCB Biopharma S.P.R.L. 12
Early research (Phase 1)Looking for participantsNCT07559474
What this trial is testing

Assess the Safety and Pharmacokinetics of INCB123667 When Administered Orally to Adult Participants With Moderate or Severe Hepatic Impairment

Who this might be right for
Hepatic InsufficiencyLiver Diseases
Incyte Corporation 16
Early research (Phase 1)Study completedNCT05718258
What this trial is testing

A Study in Adults to Investigate the Impact of Mild, Moderate, and Severe Hepatic Impairment on Pharmacokinetics of Venglustat Compared to Participants With Normal Hepatic Function

Who this might be right for
Hepatic Function Abnormal
Sanofi 26
Early research (Phase 1)Study completedNCT03440424
What this trial is testing

Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Mild and Moderate Hepatic Impairment Compared to Healthy Subjects

Who this might be right for
Hepatic Impairment
Eisai Inc. 24
Early research (Phase 1)Study completedNCT01465412
What this trial is testing

Assess Pharmacokinetics of Preladenant in Participants With Chronic Hepatic Impairment (P06513)

Who this might be right for
Chronic Hepatic Impairment
Merck Sharp & Dohme LLC 42
Early research (Phase 1)Study completedNCT05393076
What this trial is testing

Phase I Study of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Controls

Who this might be right for
Pruritus
GlaxoSmithKline 8
Early research (Phase 1)Study completedNCT05935033
What this trial is testing

Evaluate the Effect of Hepatic Impairment on the Pharmacokinetics of Emraclidine

Who this might be right for
Hepatic Impairment
AbbVie 38
Early research (Phase 1)Looking for participantsNCT07023354
What this trial is testing

Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems

Who this might be right for
HealthyHepatic Impairment
Boehringer Ingelheim 32
Early research (Phase 1)Looking for participantsNCT07401862
What this trial is testing

Eloralintide (LY3841136) in Participants With Different Levels of Liver Damage and in Participants With Healthy Livers.

Who this might be right for
Hepatic Insufficiency
Eli Lilly and Company 36
Early research (Phase 1)Ended earlyNCT05209295
What this trial is testing

Evaluate CC-486/Onureg in Participants With Moderate or Severe Hepatic Impairment Compared With Normal Hepatic Function in Participants With Myeloid Malignancies

Who this might be right for
Hepatic InsufficiencyNeoplasms
Bristol-Myers Squibb 2
Early research (Phase 1)Not Yet RecruitingNCT05093972
What this trial is testing

Ulonivirine (MK-8507) in Participants With Mild or Moderate Hepatic Impairment (MK-8507-014)

Who this might be right for
Hepatic Insufficiency
Merck Sharp & Dohme LLC 22
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