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Results for “Pathologic Stage III Gastroesophageal Junction Adenocarcinoma”

26 trials

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Showing 20 of 26 results

Early research (Phase 1)Active Not RecruitingNCT04007744
What this trial is testing

Sonidegib and Pembrolizumab in Treating Patients With Advanced Solid Tumors

Who this might be right for
Clinical Stage III Cutaneous Melanoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+19 more
Mayo Clinic 36
Testing effectiveness (Phase 2)Study completedNCT04097028
What this trial is testing

Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma

Who this might be right for
Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage III Esophageal Adenocarcinoma AJCC v8+13 more
Roswell Park Cancer Institute 22
Very early researchStudy completedNCT03395847
What this trial is testing

Pembrolizumab in Treating Patients With Metastatic or Unresectable Gastroesophageal Adenocarcinoma

Who this might be right for
Advanced Gastroesophageal Junction AdenocarcinomaClinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Gastric Cancer AJCC v8+22 more
M.D. Anderson Cancer Center 9
Early research (Phase 1)Looking for participantsNCT04704661
What this trial is testing

Testing the Combination of Two Anti-cancer Drugs, DS-8201a and AZD6738, for The Treatment of Advanced Solid Tumors Expressing the HER2 Protein or Gene, The DASH Trial

Who this might be right for
Advanced Breast CarcinomaAdvanced Colon CarcinomaAdvanced Colorectal Carcinoma+37 more
National Cancer Institute (NCI) 51
Testing effectiveness (Phase 2)Looking for participantsNCT04660760
What this trial is testing

Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer

Who this might be right for
Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+28 more
Academic and Community Cancer Research United
Large-scale testing (Phase 3)Study completedNCT02625623
What this trial is testing

Avelumab in Third-Line Gastric Cancer (JAVELIN Gastric 300)

Who this might be right for
Unresectable, Recurrent, Locally Advanced or Metastatic Gastric or Gastroesophageal Junction AdenocarcinomaGastric Cancer Third Line
EMD Serono Research & Development Institute, Inc. 371
Early research (Phase 1)WithdrawnNCT05296005
What this trial is testing

Neoadjuvant Therapy for the Treatment of Gastroesophageal Junction and Gastric Cancers

Who this might be right for
Clinical Stage I Gastric Cancer AJCC v8Clinical Stage II Gastric Cancer AJCC v8Clinical Stage IIA Gastric Cancer AJCC v8+22 more
Ohio State University Comprehensive Cancer Center
Not applicableLooking for participantsNCT05334069
What this trial is testing

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

Who this might be right for
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAnn Arbor Stage I Lymphoma+59 more
Alliance for Clinical Trials in Oncology 2,000
Early research (Phase 1)Active Not RecruitingNCT04460937
What this trial is testing

Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers

Who this might be right for
Clinical Stage III Esophageal Adenocarcinoma AJCC v8Clinical Stage III Esophageal Squamous Cell Carcinoma AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8+56 more
National Cancer Institute (NCI)
Early research (Phase 1)Looking for participantsNCT04511039
What this trial is testing

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

Who this might be right for
Advanced Malignant Solid NeoplasmClinical Stage III Gastroesophageal Junction AdenocarcinomaClinical Stage IV Gastroesophageal Junction Adenocarcinoma+26 more
Roswell Park Cancer Institute 45
Large-scale testing (Phase 3)UnknownNCT04393584
What this trial is testing

FOLFIRINOX vs FLOT Chemotherapy for Resectable Gastric or Esophagogastric Junction Adenocarcinoma

Who this might be right for
Stomach NeoplasmsGastrointestinal NeoplasmsDocetaxel+3 more
Blokhin's Russian Cancer Research Center 538
Not applicableStudy completedNCT03707574
What this trial is testing

Genetic Analysis of Blood and Tissue Samples From Patients With Advanced Cancer, Moonshot Study

Who this might be right for
Advanced Malignant NeoplasmAdvanced MelanomaAdvanced Renal Cell Carcinoma+51 more
National Cancer Institute (NCI) 64
Testing effectiveness (Phase 2)Active Not RecruitingNCT04929392
What this trial is testing

Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer

Who this might be right for
Clinical Stage I Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IIA Gastroesophageal Junction Adenocarcinoma AJCC v8+16 more
City of Hope Medical Center
Early research (Phase 1)Active Not RecruitingNCT04522336
What this trial is testing

Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer

Who this might be right for
Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8+16 more
M.D. Anderson Cancer Center
Testing effectiveness (Phase 2)Active Not RecruitingNCT03784326
What this trial is testing

Phase I/II Study of Perioperative Chemotherapy Plus Immunotherapy Followed by Surgery in Localized Esophageal and Gastroesophageal Adenocarcinoma

Who this might be right for
Clinical Stage II Esophageal Adenocarcinoma AJCC v8Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IIA Esophageal Adenocarcinoma AJCC v8+21 more
M.D. Anderson Cancer Center
Large-scale testing (Phase 3)Study completedNCT00978549
What this trial is testing

Symptom Control With or Without Docetaxel in Treating Patients With Relapsed Esophageal Cancer or Stomach Cancer

Who this might be right for
Adenocarcinoma of the Gastroesophageal JunctionEsophageal CancerGastric Cancer+2 more
Cambridge University Hospitals NHS Foundation Trust 320
Testing effectiveness (Phase 2)Looking for participantsNCT04771520
What this trial is testing

Avapritinib for the Treatment of CKIT or PDGFRA Mutation-Positive Locally Advanced or Metastatic Malignant Solid Tumors

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8+26 more
M.D. Anderson Cancer Center
Early research (Phase 1)Active Not RecruitingNCT04391049
What this trial is testing

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

Who this might be right for
Advanced Esophageal AdenocarcinomaAdvanced Gastroesophageal Junction AdenocarcinomaClinical Stage II Esophageal Adenocarcinoma AJCC v8+30 more
NRG Oncology 16
Early research (Phase 1)Looking for participantsNCT06364410
What this trial is testing

Testing the Combination of the Anticancer Drugs Trastuzumab Deruxtecan (DS-8201a) and Azenosertib (ZN-c3) in Patients With Stomach or Other Solid Tumors

Who this might be right for
Clinical Stage III Gastric Cancer AJCC v8Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8Clinical Stage IV Gastric Cancer AJCC v8+10 more
National Cancer Institute (NCI) 48
Large-scale testing (Phase 3)Study completedNCT02625610
What this trial is testing

Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)

Who this might be right for
Unresectable, Locally Advanced or Metastatic, Adenocarcinoma of the Stomach, or of the Gastro Esophageal Junction
EMD Serono Research & Development Institute, Inc. 499
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