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Results for “Pediatric Heterozygous Hypercholesterolemia”

14 trials

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Showing 14 of 14 results

Early research (Phase 1)Study completedNCT00739999
What this trial is testing

8-Week PK/PD Atorvastatin Study In Children And Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Pediatric Heterozygous Hypercholesterolemia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 39
Large-scale testing (Phase 3)Study completedNCT00867165
What this trial is testing

Pediatric Study to Evaluate the Efficacy and Safety of Ezetimibe Monotherapy in Children With Primary Hypercholesterolemia (P05522)

Who this might be right for
Primary Hypercholesterolemia
Organon and Co 138
Large-scale testing (Phase 3)Study completedNCT00355615
What this trial is testing

PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatin

Who this might be right for
Familial Hypercholesterolemia
AstraZeneca 173
Large-scale testing (Phase 3)Looking for participantsNCT06597019
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 60
Not applicableLooking for participantsNCT07470723
What this trial is testing

The ORIGIN-FH Study

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)Homozygous Familial Hypercholesterolemia (HoFH)Familial Hypercholesterolemia
University of Wisconsin, Madison 70
Large-scale testing (Phase 3)Looking for participantsNCT07058077
What this trial is testing

Enlicitide Decanoate (MK-0616, an Oral PCSK9 Inhibitor) in Children and Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0616-029)

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
Merck Sharp & Dohme LLC 153
Large-scale testing (Phase 3)Study completedNCT00827606
What this trial is testing

Atorvastatin Three Year Pediatric Study

Who this might be right for
Familial Hypercholesterolemia
Pfizer's Upjohn has merged with Mylan to form Viatris Inc. 272
Large-scale testing (Phase 3)Study completedNCT04652726
What this trial is testing

Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Familial Hypercholesterolemia - Heterozygous
Novartis Pharmaceuticals 141
Post-approval studies (Phase 4)Study completedNCT00145574
What this trial is testing

Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesterol

Who this might be right for
Hypercholesterolemia
Daiichi Sankyo 194
Large-scale testing (Phase 3)Study completedNCT02624869
What this trial is testing

Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia)

Who this might be right for
Familial Hypercholesterolemia
Amgen 163
Large-scale testing (Phase 3)Looking for participantsNCT05682378
What this trial is testing

Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies

Who this might be right for
Heterozygous or Homozygous Familial Hypercholesterolemia
Novartis Pharmaceuticals 195
Large-scale testing (Phase 3)Study completedNCT02392559
What this trial is testing

Trial Assessing Efficacy, Safety and Tolerability of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition in Paediatric Subjects With Genetic Low-Density Lipoprotein (LDL) Disorders

Who this might be right for
Heterozygous Familial Hypercholesterolemia
Amgen 158
Large-scale testing (Phase 3)Not Yet RecruitingNCT07775339
What this trial is testing

Long-Term Efficacy and Safety of Lerodalcibep in Children and Adolescents With Familial Hypercholesterolemia

Who this might be right for
Heterozygous Familial Hypercholesterolemia (HeFH)
LIB Therapeutics LLC 150
Testing effectiveness (Phase 2)Study completedNCT05694260
What this trial is testing

A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1)

Who this might be right for
Hypercholesterolemia
Esperion Therapeutics, Inc. 31